Gene name:
MRC1 (CLEC13D;CLEC13DL;MRC1L1) ;
Protein name:
Macrophage mannose receptor 1 (MMR) ;
Alternative:
C-type lectin domain family 13 member D-like ;C-type lectin domain family 13 member D ;Macrophage mannose receptor 1-like protein 1 ;
CD:
CD206 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
Subcellular Location:
Endosome membrane
Single-pass type I membrane protein
Cell membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MRLPLLLVFA | SVIPGAVLLL | DTRQFLIYNE | DHKRCVDAVS | PSAVQTAACN |
100:
QDAESQKFRW | VSESQIMSVA | FKLCLGVPSK | TDWVAITLYA | CDSKSEFQKW |
150:
ECKNDTLLGI | KGEDLFFNYG | NRQEKNIMLY | KGSGLWSRWK | IYGTTDNLCS |
200:
RGYEAMYTLL | GNANGATCAF | PFKFENKWYA | DCTSAGRSDG | WLWCGTTTDY |
250:
DTDKLFGYCP | LKFEGSESLW | NKDPLTSVSY | QINSKSALTW | HQARKSCQQQ |
300:
NAELLSITEI | HEQTYLTGLT | SSLTSGLWIG | LNSLSFNSGW | QWSDRSPFRY |
350:
LNWLPGSPSA | EPGKSCVSLN | PGKNAKWENL | ECVQKLGYIC | KKGNTTLNSF |
400:
VIPSESDVPT | HCPSQWWPYA | GHCYKIHRDE | KKIQRDALTT | CRKEGGDLTS |
450:
IHTIEELDFI | ISQLGYEPND | ELWIGLNDIK | IQMYFEWSDG | TPVTFTKWLR |
500:
GEPSHENNRQ | EDCVVMKGKD | GYWADRGCEW | PLGYICKMKS | RSQGPEIVEV |
550:
EKGCRKGWKK | HHFYCYMIGH | TLSTFAEANQ | TCNNENAYLT | TIEDRYEQAF |
600:
LTSFVGLRPE | KYFWTGLSDI | QTKGTFQWTI | EEEVRFTHWN | SDMPGRKPGC |
650:
VAMRTGIAGG | LWDVLKCDEK | AKFVCKHWAE | GVTHPPKPTT | TPEPKCPEDW |
700:
GASSRTSLCF | KLYAKGKHEK | KTWFESRDFC | RALGGDLASI | NNKEEQQTIW |
750:
RLITASGSYH | KLFWLGLTYG | SPSEGFTWSD | GSPVSYENWA | YGEPNNYQNV |
800:
EYCGELKGDP | TMSWNDINCE | HLNNWICQIQ | KGQTPKPEPT | PAPQDNPPVT |
850:
EDGWVIYKDY | QYYFSKEKET | MDNARAFCKR | NFGDLVSIQS | ESEKKFLWKY |
900:
VNRNDAQSAY | FIGLLISLDK | KFAWMDGSKV | DYVSWATGEP | NFANEDENCV |
950:
TMYSNSGFWN | DINCGYPNAF | ICQRHNSSIN | ATTVMPTMPS | VPSGCKEGWN |
1000:
FYSNKCFKIF | GFMEEERKNW | QEARKACIGF | GGNLVSIQNE | KEQAFLTYHM |
1050:
KDSTFSAWTG | LNDVNSEHTF | LWTDGRGVHY | TNWGKGYPGG | RRSSLSYEDA |
1100:
DCVVIIGGAS | NEAGKWMDDT | CDSKRGYICQ | TRSDPSLTNP | PATIQTDGFV |
1150:
KYGKSSYSLM | RQKFQWHEAE | TYCKLHNSLI | ASILDPYSNA | FAWLQMETSN |
1200:
ERVWIALNSN | LTDNQYTWTD | KWRVRYTNWA | ADEPKLKSAC | VYLDLDGYWK |
1250:
TAHCNESFYF | LCKRSDEIPA | TEPPQLPGRC | PESDHTAWIP | FHGHCYYIES |
1300:
SYTRNWGQAS | LECLRMGSSL | VSIESAAESS | FLSYRVEPLK | SKTNFWIGLF |
1350:
RNVEGTWLWI | NNSPVSFVNW | NTGDPSGERN | DCVALHASSG | FWSNIHCSSY |
1400:
KGYICKRPKI | IDAKPTHELL | TTKADTRKMD | PSKPSSNVAG | VVIIVILLIL |
1450:
TGAGLAAYFF | YKKRRVHLPQ | EGAFENTLYF | NSQSSPGTSD | MKDLVGNIEQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Polyclonal Antibody for Human MMR
Polyclonal Antibody for Human MMR
Monoclonal Antibody for Human MMR
Monoclonal Antibody for Human MMR
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
tissue :
Placenta .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANTS SER-396; ALA-399 AND PHE-407
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STUDIES ON THE BINDING OF INDIVIDUAL LECTIN DOMAINS
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1205
tissue :
Milk .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 642-788
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : POLYMORPHISM;POSSIBLE ASSOCIATION OF VARIANT SER-396 WITH RESISTANCE TO LEPROSY;VARIANTS ILE-167; ALA-399 AND PHE-407;SUBCELLULAR LOCATION