MSLN ELISA Kit for Human(Homo sapiens) | EIAab.comMSLN ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MSLN(Gene name) > Human

MSLN (Gene name),

Mesothelin (Protein name ), MSLN_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MSLN(MPF);

Protein name:

Mesothelin;

Alternative:

Pre-pro-megakaryocyte-potentiating factor;CAK1 antigen;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with MUC16.

Function:

Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.

Subcellular Location:

Isoform 3 Secreted

Protein Attributes:

Sequence length:

630

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

630:

MQEALSGTPC | LLGPGPVLTV | LALLLASTLA |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

601051

UniGene:

Hs.408488

KEGG:

hsa:10232

Pfam:

PF06060

String:

Q13421

SMR:

Q13421

Uniprot:

Q13421

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ELISA Kit for Human Mesothelin

Cat.:

E2255h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human Mesothelin

Cat.:

E2255m

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Packing:

96T

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ELISA Kit for Human Mesothelin

Cat.:

E2255r

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96T

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CLIA Kit for Human Mesothelin

Cat.:

U2255m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Mesothelin

Cat.:

U2255h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Mesothelin

Cat.:

U2255r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Mesothelin

Cat.:

P2255Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Mesothelin

Cat.:

P2255Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Mesothelin

Cat.:

P2255Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Mesothelin

Protein for Human Mesothelin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular cloning and expression of megakaryocyte potentiating factor cDNA."
Kojima T. , Oh-Eda M. , Hattori K. , Taniguchi Y. , Tamura M. , Ochi N. , Yamaguchi N.
J. Biol. Chem.270:21984-21990(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);PROTEIN SEQUENCE OF 37-54 AND 90-117;TISSUE SPECIFICITY;VARIANT VAL-601
tissue: Pancreatic cancer.
2.

"Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers."
Chang K. , Pastan I.
Proc. Natl. Acad. Sci. U.S.A.93:136-140(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION;GPI-ANCHOR;GLYCOSYLATION;CLEAVAGE;VARIANT VAL-601
tissue: Carcinoma.
3.

"Characterization of human mesothelin transcripts in ovarian and pancreatic cancer."
Muminova Z.E. , Strong T.V. , Shaw D.R.
BMC Cancer4:19-19(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);ALTERNATIVE SPLICING (ISOFORMS 2 AND 3)
4.

"Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients."
Ho M. , Hassan R. , Zhang J. , Wang Q.-C. , Onda M. , Bera T. , Pastan I.
Clin. Cancer Res.11:3814-3820(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);DISEASE;VARIANT VAL-601
tissue: Lung.
tissue: Spleen.
5.

"Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."
Daniels R.J. , Peden J.F. , Lloyd C. , Horsley S.W. , Clark K. , Tufarelli C. , Kearney L. , Buckle V.J. , Doggett N.A. , Flint J. , Higgs D.R.
Hum. Mol. Genet.10:339-352(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The sequence and analysis of duplication-rich human chromosome 16."
Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT VAL-601
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4);VARIANTS PRO-309 AND VAL-601
tissue: Pancreas.
tissue: Placenta.
9.

"A novel cytokine exhibiting megakaryocyte potentiating activity from a human pancreatic tumor cell line HPC-Y5."
Yamaguchi N. , Hattori K. , Oh-eda M. , Kojima T. , Imai N. , Ochi N.
J. Biol. Chem.269:805-808(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 37-54 (ISOFORMS 1/2/3);GLYCOSYLATION;FUNCTION
tissue: Pancreatic tumor.
10.

"Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma."
Scholler N. , Fu N. , Yang Y. , Ye Z. , Goodman G.E. , Hellstroem K.E. , Hellstroem I.
Proc. Natl. Acad. Sci. U.S.A.96:11531-11536(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 297-630 (ISOFORM 3);PROTEIN SEQUENCE OF 296-314;VARIANT VAL-601
11.

"Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion."
Rump A. , Morikawa Y. , Tanaka M. , Minami S. , Umesaki N. , Takeuchi M. , Miyajima A.
J. Biol. Chem.279:9190-9198(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MUC16;FUNCTION
12.

"Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma."
Onda M. , Nagata S. , Ho M. , Bera T.K. , Hassan R. , Alexander R.H. , Pastan I.
Clin. Cancer Res.12:4225-4231(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION;TISSUE SPECIFICITY
13.

"Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment."
Elortza F. , Mohammed S. , Bunkenborg J. , Foster L.J. , Nuehse T.S. , Brodbeck U. , Peck S.C. , Jensen O.N.
J. Proteome Res.5:935-943(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights."
Ma J. , Tang W.K. , Esser L. , Pastan I. , Xia D.
J. Biol. Chem.287:33123-33131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS) OF 302-359 IN COMPLEX WITH ANTOBODY;SUBCELLULAR LOCATION;DISULFIDE BOND

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