Gene name:
MUC20 (UNQ2782/PRO7170;KIAA1359) ;
Protein name:
Mucin-20 (MUC-20) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with MET; oligomerization increases affinity for MET.
Function:
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Subcellular Location:
Secreted
Apical cell membrane
Basolateral cell membrane
Cell projection
microvillus membrane
Protein Attributes:
50:
MGCLWGLALP | LFFFCWEVGV | SGSSAGPSTR | RADTAMTTDD | TEVPAMTLAP |
100:
GHAALETQTL | SAETSSRAST | PAGPIPEAET | RGAKRISPAR | ETRSFTKTSP |
150:
NFMVLIATSV | ETSAASGSPE | GAGMTTVQTI | TGSDPREAIF | DTLCTDDSSE |
200:
EAKTLTMDIL | TLAHTSTEAK | GLSSESSASS | DSPHPVITPS | RASESSASSD |
250:
GPHPVITPSR | ASESSASSDG | PHPVITPSRA | SESSASSDGP | HPVITPSRAS |
300:
ESSASSDGPH | PVITPSRASE | SSASSDGPHP | VITPSRASES | SASSDGPHPV |
350:
ITPSRASESS | ASSDGPHPVI | TPSRASESSA | SSDGPHPVIT | PSRASESSAS |
400:
SDGLHPVITP | SRASESSASS | DGPHPVITPS | RASESSASSD | GPHPVITPSW |
450:
SPGSDVTLLA | EALVTVTNIE | VINCSITEIE | TTTSSIPGAS | DTDLIPTEGV |
500:
KASSTSDPPA | LPDSTEAKPH | ITEVTASAET | LSTAGTTESA | APDATVGTPL |
550:
PTNSATEREV | TAPGATTLSG | ALVTVSRNPL | EETSALSVET | PSYVKVSGAA |
600:
PVSIEAGSAV | GKTTSFAGSS | ASSYSPSEAA | LKNFTPSETP | TMDIATKGPF |
650:
PTSRDPLPSV | PPTTTNSSRG | TNSTLAKITT | SAKTTMKPPT | ATPTTARTRP |
700:
TTDVSAGENG | GFLLLRLSVA | SPEDLTDPRV | AERLMQQLHR | ELHAHAPHFQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human MUC-20
ELISA Kit for Human MUC-20
CLIA Kit for Human MUC-20
CLIA Kit for Human MUC-20
Polyclonal Antibody for Human MUC-20
Polyclonal Antibody for Human MUC-20
Monoclonal Antibody for Human MUC-20
Monoclonal Antibody for Human MUC-20
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2);VARIANTS 184-HIS--LEU-354 DEL; 241-HIS--LEU-354 DEL AND ILE-442;POLYMORPHISM;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS 184-HIS--LEU-354 DEL AND ILE-442
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS 184-HIS--LEU-354 DEL; ILE-442 AND 483-THR--THR-533 DEL
tissue :
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS 184-HIS--LEU-354 DEL; 203-HIS--LEU-354; DEL ILE-442 AND LEU-590
tissue :
Brain .
tissue :
Colon .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 26-638 (ISOFORM 1);VARIANT 241-HIS--LEU-354 DEL
tissue :
Brain .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH MET
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TANDEM REPEATS POLYMORPHISM
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY