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Index > Protein center > MYL3(Gene name) > Human
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  • MYL3 (Gene name),
  • Myosin light chain 3 (Protein name ),  MYL3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MYL3;
    Protein name:
    Myosin light chain 3;
    Alternative:
    Myosin light chain 1, slow-twitch muscle B/ventricular isoform(MLC1SB);Cardiac myosin light chain 1(CMLC1);Ventricular/slow twitch myosin alkali light chain;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Myosin is an hexamer of 2 heavy chains and 4 light chains.
    Function:
    Regulatory light chain of myosin. Does not bind calcium.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    195
    Sequence:
    50:
    MAPKKPEPKK | DDAKAAPKAA | PAPAPPPEPE | RPKEVEFDAS | KIKIEFTPEQ | 
    100:
    IEEFKEAFML | FDRTPKCEMK | ITYGQCGDVL | RALGQNPTQA | EVLRVLGKPR | 
    150:
    QEELNTKMMD | FETFLPMLQH | ISKNKDTGTY | EDFVEGLRVF | DKEGNGTVMG | 
    195:
    AELRHVLATL | GERLTEDEVE | KLMAGQEDSN | GCINYEAFVK | HIMSS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Myosin light chain 3
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    E1391h
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    96T
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    ELISA Kit for Human Myosin light chain 3
    Cat.:
    E1391r
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    96T
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    ELISA Kit for Human Myosin light chain 3
    Cat.:
    E1391b
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    Packing:
    96T
    ELISA Kit for Human Myosin light chain 3
    Cat.:
    E1391m
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    Packing:
    96T
    CLIA Kit for Human Myosin light chain 3
    Cat.:
    U1391h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Myosin light chain 3
    Cat.:
    U1391b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Myosin light chain 3
    Cat.:
    U1391r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Myosin light chain 3
    Cat.:
    U1391m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Myosin light chain 3
    Cat.:
    P1391Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Myosin light chain 3
    Polyclonal Antibody for Human Myosin light chain 3
    Cat.:
    P1391Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Myosin light chain 3
    Cat.:
    P1391Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Myosin light chain 3
    Monoclonal Antibody for Human Myosin light chain 3
    Cat.:
    M1391h
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    Packing:
    40ug
    Monoclonal Antibody for Human Myosin light chain 3
    Cat.:
    M1391r
    Price:
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    Packing:
    40ug
    Monoclonal Antibody for Human Myosin light chain 3
    Protein for Human Myosin light chain 3
    Protein for Human Myosin light chain 3
    Protein for Human Myosin light chain 3
    Protein for Human Myosin light chain 3

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    References
    1. 1.
      "Molecular cloning and characterization of human atrial and ventricular myosin alkali light chain cDNA clones."
      Kurabayashi M. , Komuro I. , Tsuchimochi H. , Takaku F. , Yazaki Y.
      J. Biol. Chem.263:13930-13936(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Molecular cloning and complete nucleotide sequence of a human ventricular myosin light chain 1."
      Hoffmann E. , Shi Q.W. , Floroff M. , Mickle D.A.G. , Wu T.-W. , Olley P.M. , Jackowski G.
      Nucleic Acids Res.16:2353-2353(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      Jackowski G.
      Submitted (1988-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    4. 4.
      "Human ventricular/slow twitch myosin alkali light chain gene characterization, sequence, and chromosomal location."
      Fodor W.L. , Darras B. , Seharaseyon J. , Falkenthal S. , Francke U. , Vanin E.F.
      J. Biol. Chem.264:2143-2149(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "The sequence of human cardiac myosin light chain I (CMLC-1) from a Chinese patient and the preparation of monoclonal antibody to CHCMLC1."
      Huang R. , Peng B. , Zhou G. , Gong Z.
      Submitted (1999-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skeletal muscle.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skeletal muscle.
    9. 9.
      "The major protein expression profile and two-dimensional protein database of human heart."
      Kovalyov L.I. , Shishkin S.S. , Efimochkin A.S. , Kovalyova M.A. , Ershova E.S. , Egorov T.A. , Musalyamov A.K.
      Electrophoresis16:1160-1169(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-27; 34-40; 95-100; 124-129; 139-142 AND 155-171
      tissue: Heart.
    10. 10.
      "The widespread distribution of alpha-N-trimethylalanine as the N-terminal amino acid of light chains from vertebrate striated muscle myosins."
      Henry G.D. , Trayer I.P. , Brewer S. , Levine B.A.
      Eur. J. Biochem.148:75-82(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METHYLATION AT ALA-2
    11. 11.
      "Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle."
      Poetter K. , Jiang H. , Hassanzadeh S. , Master S.R. , Chang A. , Dalakas M.C. , Rayment I. , Sellers J.R. , Fananapazir L. , Epstein N.D.
      Nat. Genet.13:63-69(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMH8 VAL-149 AND HIS-154
    12. 12.
      "Myosin light chain mutation causes autosomal recessive cardiomyopathy with mid-cavitary hypertrophy and restrictive physiology."
      Olson T.M. , Karst M.L. , Whitby F.G. , Driscoll D.J.
      Circulation105:2337-2340(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMH8 LYS-143
    13. 13.
      "Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy."
      Richard P. , Charron P. , Carrier L. , Ledeuil C. , Cheav T. , Pichereau C. , Benaiche A. , Isnard R. , Dubourg O. , Burban M. , Gueffet J.-P. , Millaire A. , Desnos M. , Schwartz K. , Hainque B. , Komajda M.
      Circulation107:2227-2232(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMH8 GLY-56
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
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