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Index > Protein center > NAMPT(Gene name) > Human
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  • NAMPT (Gene name),
  • Nicotinamide phosphoribosyltransferase (Protein name ),  NAMPT_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (1)
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  • Gene name:
    NAMPT(PBEF;PBEF1);
    Protein name:
    Nicotinamide phosphoribosyltransferase(NAmPRTase;Nampt);
    Alternative:
    Visfatin;Pre-B-cell colony-enhancing factor 1(Pre-B cell-enhancing factor);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    491
    Sequence:
    50:
    MNPAAEAEFN | ILLATDSYKV | THYKQYPPNT | SKVYSYFECR | EKKTENSKLR | 
    100:
    KVKYEETVFY | GLQYILNKYL | KGKVVTKEKI | QEAKDVYKEH | FQDDVFNEKG | 
    150:
    WNYILEKYDG | HLPIEIKAVP | EGFVIPRGNV | LFTVENTDPE | CYWLTNWIET | 
    200:
    ILVQSWYPIT | VATNSREQKK | ILAKYLLETS | GNLDGLEYKL | HDFGYRGVSS | 
    250:
    QETAGIGASA | HLVNFKGTDT | VAGLALIKKY | YGTKDPVPGY | SVPAAEHSTI | 
    300:
    TAWGKDHEKD | AFEHIVTQFS | SVPVSVVSDS | YDIYNACEKI | WGEDLRHLIV | 
    350:
    SRSTQAPLII | RPDSGNPLDT | VLKVLEILGK | KFPVTENSKG | YKLLPPYLRV | 
    400:
    IQGDGVDINT | LQEIVEGMKQ | KMWSIENIAF | GSGGGLLQKL | TRDLLNCSFK | 
    450:
    CSYVVTNGLG | INVFKDPVAD | PNKRSKKGRL | SLHRTPAGNF | VTLEEGKGDL | 
    491:
    EEYGQDLLHT | VFKNGKVTKS | YSFDEIRKNA | QLNIELEAAH | H
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    KEGG:
    SMR:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human NAmPRTase
    Cat.:
    E0638p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human NAmPRTase
    Cat.:
    E0638r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human NAmPRTase
    Cat.:
    E0638m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human NAmPRTase
    Cat.:
    E0638h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human NAmPRTase
    Cat.:
    U0638h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human NAmPRTase
    Cat.:
    U0638m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NAmPRTase
    Cat.:
    U0638r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NAmPRTase
    Cat.:
    U0638p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human NAmPRTase
    Cat.:
    P0638Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NAmPRTase
    Cat.:
    P0638Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NAmPRTase
    Cat.:
    P0638Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NAmPRTase
    Monoclonal Antibody for Human NAmPRTase
    Monoclonal Antibody for Human NAmPRTase
    Monoclonal Antibody for Human NAmPRTase
    Monoclonal Antibody for Human NAmPRTase
    Protein for Human NAmPRTase
    Protein for Human NAmPRTase
    Protein for Human NAmPRTase
    Protein for Human NAmPRTase
    Cat.:
    R0638h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

    R&D Technical Data
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    12% SDS-PAGE analysis

                12% SDS-PAGE analysis


    wb

            Western blot - Anti-NAMPT antibody

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor."
      Samal B. , Sun Y. , Stearns G. , Xie C. , Suggs S. , McNiece I.
      Mol. Cell. Biol.14:1431-1437(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Blood.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Trachea.
    3. 3.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
      tissue: Skin.
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 8.
      "Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology."
      Dahl T.B. , Holm S. , Aukrust P. , Halvorsen B.
      Annu. Rev. Nutr.32:229-243(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    8. 9.
      "Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth."
      Bienertova-Vasku J. , Bienert P. , Zlamal F. , Tomandl J. , Tomandlova M. , Dostalova Z. , Vasku A.
      Diabetes Res. Clin. Pract.96:355-361(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    9. 10.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 11.
      "Visfatin as a novel mediator released by inflamed human endothelial cells."
      Romacho T. , Villalobos L.A. , Cercas E. , Carraro R. , Sanchez-Ferrer C.F. , Peiro C.
      PLoS ONE8:E78283-E78283(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    11. 12.
      "Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents."
      Khan J.A. , Tao X. , Tong L.
      Nat. Struct. Mol. Biol.13:582-588(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) IN COMPLEXES WITH SUBSTRATE; PRODUCT AND INHIBITOR FK866;ENZYME REGULATION;MUTAGENESIS OF ASP-219; HIS-247 AND ARG-311;SUBUNIT
    12. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] SER-176
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