Protein name:
Nicotinamide phosphoribosyltransferase (NAmPRTase;Nampt) ;
Alternative:
Visfatin ;Pre-B-cell colony-enhancing factor 1 homolog (PBEF) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
Subcellular Location:
Cytoplasm
Nucleus
Protein Attributes:
50:
MNAAAEAEFN | ILLATDSYKV | THYKQYPPNT | SKVYSYFECR | EKKTENSKVR |
100:
KVKYEETVFY | GLQYILNKYL | KGKVVTKEKI | QEAKEVYREH | FQDDVFNERG |
150:
WNYILEKYDG | HLPIEVKAVP | EGSVIPRGNV | LFTVENTDPE | CYWLTNWIET |
200:
ILVQSWYPIT | VATNSREQKK | ILAKYLLETS | GNLDGLEYKL | HDFGYRGVSS |
250:
QETAGIGASA | HLVNFKGTDT | VAGIALIKKY | YGTKDPVPGY | SVPAAEHSTI |
300:
TAWGKDHEKD | AFEHIVTQFS | SVPVSVVSDS | YDIYNACEKI | WGEDLRHLIV |
350:
SRSTEAPLII | RPDSGNPLDT | VLKVLDILGK | KFPVSENSKG | YKLLPPYLRV |
400:
IQGDGVDINT | LQEIVEGMKQ | KKWSIENVSF | GSGGALLQKL | TRDLLNCSFK |
450:
CSYVVTNGLG | VNVFKDPVAD | PNKRSKKGRL | SLHRTPAGTF | VTLEEGKGDL |
491:
EEYGHDLLHT | VFKNGKVTKS | YSFDEVRKNA | QLNMEQDVAP | H
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Rat
Mouse
Human
ELISA Kit for Rat NAmPRTase
ELISA Kit for Rat NAmPRTase
ELISA Kit for Rat NAmPRTase
ELISA Kit for Rat NAmPRTase
CLIA Kit for Rat NAmPRTase
CLIA Kit for Rat NAmPRTase
CLIA Kit for Rat NAmPRTase
CLIA Kit for Rat NAmPRTase
Polyclonal Antibody for Rat NAmPRTase
Polyclonal Antibody for Rat NAmPRTase
Polyclonal Antibody for Rat NAmPRTase
Polyclonal Antibody for Rat NAmPRTase
Monoclonal Antibody for Rat NAmPRTase
Monoclonal Antibody for Rat NAmPRTase
Monoclonal Antibody for Rat NAmPRTase
Monoclonal Antibody for Rat NAmPRTase
Protein for Rat NAmPRTase
Protein for Rat NAmPRTase
Protein for Rat NAmPRTase
Protein for Rat NAmPRTase
R&D Technical Data
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12% SDS-PAGE analysis
Western blot - Anti-NAMPT antibody
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
2.
"NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase attenuates ischemic neuronal cell death."
Xing J.
,
Gao Y.
,
Cao G.
,
Chen J.
Submitted (2004-11) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley . tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Heart .
4.
"Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866."
Kim M.-K.
,
Lee J.H.
,
Kim H.
,
Park S.J.
,
Kim S.H.
,
Kang G.B.
,
Lee Y.S.
,
Kim J.B.
,
Kim K.K.
,
Suh S.W.
,
Eom S.H.
J. Mol. Biol.362:66-77(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEXES WITH NICOTINAMIDE MONONUCLEOTIDE AND FK866;SUBUNIT
Vaild Sequence:
