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Index > Protein center > NCOA1(Gene name) > Human
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  • NCOA1 (Gene name),
  • Nuclear receptor coactivator 1 (Protein name ),  NCOA1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    NCOA1(BHLHE74;SRC1);
    Protein name:
    Nuclear receptor coactivator 1(NCoA-1);
    Alternative:
    Protein Hin-2;Class E basic helix-loop-helix protein 74(bHLHe74);Renal carcinoma antigen NY-REN-52;RIP160;Steroid receptor coactivator 1(SRC-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with the methyltransferase CARM1 (By similarity). Interacts with NCOA6 and NCOA2. Interacts with the FDL motif of STAT5A and STAT5B. Interacts with the LXXLL motif of STAT6. Interacts with STAT3 following IL-6 stimulation. Interacts with the basal transcription factor GTF2B. Interacts with the histone acetyltransferases EP300 and CREBBP. Interacts with PCAF, COPS5, NR3C1 and TTLL5/STAMP. Interacts with PSMB9. Interacts with UBE2L3; they functionally interact to regulate progesterone receptor transcriptional activity. Interacts with PRMT2.
    Function:
    Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    1441
    Sequence:
    50:
    MSGLGDSSSD | PANPDSHKRK | GSPCDTLASS | TEKRRREQEN | KYLEELAELL | 
    100:
    SANISDIDSL | SVKPDKCKIL | KKTVDQIQLM | KRMEQEKSTT | DDDVQKSDIS | 
    150:
    SSSQGVIEKE | SLGPLLLEAL | DGFFFVVNCE | GRIVFVSENV | TSYLGYNQEE | 
    200:
    LMNTSVYSIL | HVGDHAEFVK | NLLPKSLVNG | VPWPQEATRR | NSHTFNCRML | 
    250:
    IHPPDEPGTE | NQEACQRYEV | MQCFTVSQPK | SIQEDGEDFQ | SCLICIARRL | 
    300:
    PRPPAITGVE | SFMTKQDTTG | KIISIDTSSL | RAAGRTGWED | LVRKCIYAFF | 
    350:
    QPQGREPSYA | RQLFQEVMTR | GTASSPSYRF | ILNDGTMLSA | HTKCKLCYPQ | 
    400:
    SPDMQPFIMG | IHIIDREHSG | LSPQDDTNSG | MSIPRVNPSV | NPSISPAHGV | 
    450:
    ARSSTLPPSN | SNMVSTRINR | QQSSDLHSSS | HSNSSNSQGS | FGCSPGSQIV | 
    500:
    ANVALNQGQA | SSQSSNPSLN | LNNSPMEGTG | ISLAQFMSPR | RQVTSGLATR | 
    550:
    PRMPNNSFPP | NISTLSSPVG | MTSSACNNNN | RSYSNIPVTS | LQGMNEGPNN | 
    600:
    SVGFSASSPV | LRQMSSQNSP | SRLNIQPAKA | ESKDNKEIAS | ILNEMIQSDN | 
    650:
    SSSDGKPLDS | GLLHNNDRLS | DGDSKYSQTS | HKLVQLLTTT | AEQQLRHADI | 
    700:
    DTSCKDVLSC | TGTSNSASAN | SSGGSCPSSH | SSLTERHKIL | HRLLQEGSPS | 
    750:
    DITTLSVEPD | KKDSASTSVS | VTGQVQGNSS | IKLELDASKK | KESKDHQLLR | 
    800:
    YLLDKDEKDL | RSTPNLSLDD | VKVKVEKKEQ | MDPCNTNPTP | MTKPTPEEIK | 
    850:
    LEAQSQFTAD | LDQFDQLLPT | LEKAAQLPGL | CETDRMDGAV | TSVTIKSEIL | 
    900:
    PASLQSATAR | PTSRLNRLPE | LELEAIDNQF | GQPGTGDQIP | WTNNTVTAIN | 
    950:
    QSKSEDQCIS | SQLDELLCPP | TTVEGRNDEK | ALLEQLVSFL | SGKDETELAE | 
    1000:
    LDRALGIDKL | VQGGGLDVLS | ERFPPQQATP | PLIMEERPNL | YSQPYSSPSP | 
    1050:
    TANLPSPFQG | MVRQKPSLGT | MPVQVTPPRG | AFSPGMGMQP | RQTLNRPPAA | 
    1100:
    PNQLRLQLQQ | RLQGQQQLIH | QNRQAILNQF | AATAPVGINM | RSGMQQQITP | 
    1150:
    QPPLNAQMLA | QRQRELYSQQ | HRQRQLIQQQ | RAMLMRQQSF | GNNLPPSSGL | 
    1200:
    PVQMGNPRLP | QGAPQQFPYP | PNYGTNPGTP | PASTSPFSQL | AANPEASLAN | 
    1250:
    RNSMVSRGMT | GNIGGQFGTG | INPQMQQNVF | QYPGAGMVPQ | GEANFAPSLS | 
    1300:
    PGSSMVPMPI | PPPQSSLLQQ | TPPASGYQSP | DMKAWQQGAI | GNNNVFSQAV | 
    1350:
    QNQPTPAQPG | VYNNMSITVS | MAGGNTNVQN | MNPMMAQMQM | SSLQMPGMNT | 
    1400:
    VCPEQINDPA | LRHTGLYCNQ | LSSTDLLKTE | ADGTQQVQQV | QVFADVQCTV | 
    1441:
    NLVGGDPYLN | QPGPLGTQKP | TSGPQTPQAQ | QKSLLQQLLT | E
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    SMR:
    String:
    Pfam:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human NCoA-1
    Cat.:
    E0335h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human NCoA-1
    Cat.:
    E0335p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human NCoA-1
    Cat.:
    E0335m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human NCoA-1
    Cat.:
    U0335p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NCoA-1
    Cat.:
    U0335m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NCoA-1
    Cat.:
    U0335h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human NCoA-1
    Cat.:
    P0335Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NCoA-1
    Cat.:
    P0335Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NCoA-1
    Monoclonal Antibody for Human NCoA-1
    Monoclonal Antibody for Human NCoA-1
    Monoclonal Antibody for Human NCoA-1
    Protein for Human NCoA-1
    Protein for Human NCoA-1
    Protein for Human NCoA-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator."
      Takeshita A. , Yen P.M. , Misiti S. , Cardona G.R. , Liu Y. , Chin W.W.
      Endocrinology137:3594-3597(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);INTERACTION WITH GTF2B;VARIANTS LYS-457; LYS-466; PRO-474; THR-591; ALA-685; PHE-999 AND THR-1154
    2. 2.
      "Isoforms of steroid receptor coactivator 1 differ in their ability to potentiate transcription by the oestrogen receptor."
      Kalkhoven E. , Valentine J.E. , Heery D.M. , Parker M.G.
      EMBO J.17:232-243(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;TISSUE SPECIFICITY;MUTAGENESIS OF 636-LEU-LEU-637; 693-LEU-LEU-694 AND 752-LEU-LEU-753
    3. 3.
      "The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors."
      Onate S.A. , Boonyaratanakornkit V. , Spencer T.E. , Tsai S.Y. , Tsai M.-J. , Edwards D.P. , O'Malley B.W.
      J. Biol. Chem.273:12101-12108(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS LYS-457; LYS-466; PRO-474; THR-591; ALA-685; PHE-999 AND THR-1154
      tissue: Heart muscle.
      tissue: Skeletal muscle.
    4. 4.
      SeattleSNPs variation discovery resource
      Submitted (2007-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ILE-1238 AND SER-1272
    5. 5.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
    8. 8.
      "Sequence and characterization of a coactivator for the steroid hormone receptor superfamily."
      Onate S.A. , Tsai S.Y. , Tsai M.-J. , O'Malley B.W.
      Science270:1354-1357(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 363-1441 (ISOFORM 1);FUNCTION;INTERACTION WITH ESR1; RXRA; GCCR; PGR AND THRA;VARIANTS LYS-457; LYS-466; PRO-474; THR-591; ALA-685; ALA-794; PHE-999 AND THR-1154
    9. 9.
      "Analysis of human immunodeficiency virus type 1 promoter insertion in vivo."
      Raineri I. , Soler M. , Senn H.-P.
      Virology208:359-364(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 865-1441 (ISOFORM 2)
    10. 10.
      "Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1."
      Wachtel M. , Dettling M. , Koscielniak E. , Stegmaier S. , Treuner J. , Simon-Klingenstein K. , Buehlmann P. , Niggli F.K. , Schaefer B.W.
      Cancer Res.64:5539-5545(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 868-1441 (ISOFORM 2);CHROMOSOMAL TRANSLOCATION WITH PAX3;TISSUE SPECIFICITY
    11. 11.
      "A splicing variant of steroid receptor coactivator-1 (SRC-1E): the major isoform of SRC-1 to mediate thyroid hormone action."
      Hayashi Y. , Ohmori S. , Ito T. , Seo H.
      Biochem. Biophys. Res. Commun.236:83-87(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION (ISOFORM 2);FUNCTION;ALTERNATIVE SPLICING
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A HISTONE ACETYLTRANSFERASE;INTERACTION WITH PCAF
    13. 13.
      "Steroid receptor induction of gene transcription: a two-step model."
      Jenster G. , Spencer T.E. , Burcin M.M. , Tsai S.Y. , Tsai M.-J. , O'Malley B.W.
      Proc. Natl. Acad. Sci. U.S.A.94:7879-7884(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    14. 14.
      "Antigens recognized by autologous antibody in patients with renal-cell carcinoma."
      Scanlan M.J. , Gordan J.D. , Williamson B. , Stockert E. , Bander N.H. , Jongeneel C.V. , Gure A.O. , Jaeger D. , Jaeger E. , Knuth A. , Chen Y.-T. , Old L.J.
      Int. J. Cancer83:456-464(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION AS A RENAL CANCER ANTIGEN
      tissue: Renal cell carcinoma.
    15. 15.
      "A nuclear factor ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo."
      Lee S.-K. , Anzick S.L. , Choi J.-E. , Bubendorf L. , Guan X.-Y. , Jung Y.-K. , Kallioniemi O.-P. , Kononen J. , Trent J.M. , Azorsa D. , Jhun B.-H. , Cheong J.H. , Lee Y.C. , Meltzer P.S. , Lee J.W.
      J. Biol. Chem.274:34283-34293(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCOA6
    16. 16.
      "Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin."
      Liu Z. , Wong J. , Tsai S.Y. , Tsai M.-J. , O'Malley B.W.
      Proc. Natl. Acad. Sci. U.S.A.96:9485-9490(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    17. 17.
      "Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway."
      Rowan B.G. , Weigel N.L. , O'Malley B.W.
      J. Biol. Chem.275:4475-4483(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-372; SER-395; SER-517; SER-569; SER-1033; THR-1179 AND SER-1185
    18. 18.
      "JAB1 interacts with both the progesterone receptor and SRC-1."
      Chauchereau A. , Georgiakaki M. , Perrin-Wolff M. , Milgrom E. , Loosfelt H.
      J. Biol. Chem.275:8540-8548(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COPS5
    19. 19.
      "Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha."
      Carrero P. , Okamoto K. , Coumailleau P. , O'Brien S. , Tanaka H. , Poellinger L.
      Mol. Cell. Biol.20:402-415(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCOA2
    20. 20.
      "A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA."
      Watanabe M. , Yanagisawa J. , Kitagawa H. , Takeyama K. , Ogawa S. , Arao Y. , Suzawa M. , Kobayashi Y. , Yano T. , Yoshikawa H. , Masuhiro Y. , Kato S.
      EMBO J.20:1341-1352(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DDX5
    21. 21.
      "Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a."
      Giraud S. , Bienvenu F. , Avril S. , Gascan H. , Heery D.M. , Coqueret O.
      J. Biol. Chem.277:8004-8011(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STAT3
    22. 22.
      "Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha."
      Qi C. , Chang J. , Zhu Y. , Yeldandi A.V. , Rao S.M. , Zhu Y.-J.
      J. Biol. Chem.277:28624-28630(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PRMT2
    23. 23.
      "An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1."
      Litterst C.M. , Pfitzner E.
      J. Biol. Chem.277:36052-36060(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STAT6
    24. 24.
      "Sumoylation of the progesterone receptor and of the steroid receptor coactivator SRC-1."
      Chauchereau A. , Amazit L. , Quesne M. , Guiochon-Mantel A. , Milgrom E.
      J. Biol. Chem.278:12335-12343(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-732 AND LYS-774;UBIQUITINATION;MUTAGENESIS OF LYS-732; LYS-774; LYS-800; LYS-846 AND LYS-1378
    25. 25.
      "NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain."
      Litterst C.M. , Kliem S. , Marilley D. , Pfitzner E.
      J. Biol. Chem.278:45340-45351(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH STAT5A AND STAT5B
    26. 26.
      "BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation."
      Hsiao P.W. , Fryer C.J. , Trotter K.W. , Wang W. , Archer T.K.
      Mol. Cell. Biol.23:6210-6220(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NR3C1
    27. 27.
      "The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors."
      Verma S. , Ismail A. , Gao X. , Fu G. , Li X. , O'Malley B.W. , Nawaz Z.
      Mol. Cell. Biol.24:8716-8726(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UBE2L3
    28. 28.
      "The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription."
      Zhang H. , Sun L. , Liang J. , Yu W. , Zhang Y. , Wang Y. , Chen Y. , Li R. , Sun X. , Shang Y.
      EMBO J.25:4223-4233(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PSMB9
    29. 29.
      "Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor."
      Cho Y.S. , Kim E.J. , Park U.H. , Sin H.S. , Um S.J.
      J. Biol. Chem.281:17588-17598(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ASXL1
    30. 30.
      "STAMP, a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression."
      He Y. , Simons S.S. Jr.
      Mol. Cell. Biol.27:1467-1485(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TTLL5
      tissue: Testis.
    31. 31.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    32. 32.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    33. 33.
      "The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors."
      Cho Y. , Noshiro M. , Choi M. , Morita K. , Kawamoto T. , Fujimoto K. , Kato Y. , Makishima M.
      Mol. Pharmacol.76:1360-1369(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RXRA
    34. 34.
      "Protein arginine methyltransferase 6 regulates multiple aspects of gene expression."
      Harrison M.J. , Tang Y.H. , Dowhan D.H.
      Nucleic Acids Res.38:2201-2216(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PRMT6
    35. 35.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-395;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    36. 36.
      "Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma."
      Nolte R.T. , Wisely G.B. , Westin S. , Cobb J.E. , Lambert M.H. , Kurokawa R. , Rosenfeld M.G. , Willson T.M. , Glass C.K. , Milburn M.V.
      Nature395:137-143(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 623-710 IN COMPLEX WITH PPARG
    37. 37.
      "Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors."
      Xu H.E. , Lambert M.H. , Montana V.G. , Plunket K.D. , Moore L.B. , Collins J.L. , Oplinger J.A. , Kliewer S.A. , Gampe R.T. Jr. , McKee D.D. , Moore J.T. , Willson T.M.
      Proc. Natl. Acad. Sci. U.S.A.98:13919-13924(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 687-696 IN COMPLEX WITH PPARA
    38. 38.
      "Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3."
      Greschik H. , Wurtz J.-M. , Sanglier S. , Bourguet W. , van Dorsselaer A. , Moras D. , Renaud J.-P.
      Mol. Cell9:303-313(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 686-700 IN COMPLEX WITH ESRRG
    39. 39.
      "Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain."
      Razeto A. , Ramakrishnan V. , Litterst C.M. , Giller K. , Griesinger C. , Carlomagno T. , Lakomek N. , Heimburg T. , Lodrini M. , Pfitzner E. , Becker S.
      J. Mol. Biol.336:319-329(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 257-385 IN COMPLEX WITH 795-808 OF STAT6
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