Protein name:
Netrin-1 ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds to its receptors; DCC, UNC5A, UNC5B, UNC5C and probably UNC5D (By similarity). Binds to its receptor; DSCAM.
Function:
Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MMRAVWEALA | ALAAVACLVG | AVRGGPGLSM | FAGQAAQPDP | CSDENGHPRR |
100:
CIPDFVNAAF | GKDVRVSSTC | GRPPARYCVV | SERGEERLRS | CHLCNSSDPK |
150:
KAHPPAFLTD | LNNPHNLTCW | QSENYLQFPH | NVTLTLSLGK | KFEVTYVSLQ |
200:
FCSPRPESMA | IYKSMDYGRT | WVPFQFYSTQ | CRKMYNRPHR | APITKQNEQE |
250:
AVCTDSHTDM | RPLSGGLIAF | STLDGRPSAH | DFDNSPVLQD | WVTATDIRVA |
300:
FSRLHTFGDE | NEDDSELARD | SYYYAVSDLQ | VGGRCKCNGH | AARCVRDRDD |
350:
SLVCDCRHNT | AGPECDRCKP | FHYDRPWQRA | TAREANECVA | CNCNLHARRC |
400:
RFNMELYKLS | GRKSGGVCLN | CRHNTAGRHC | HYCKEGFYRD | MGKPITHRKA |
450:
CKACDCHPVG | AAGKTCNQTT | GQCPCKDGVT | GITCNRCAKG | YQQSRSPIAP |
500:
CIKIPVAPPT | TAASSVEEPE | DCDSYCKASK | GKLKMNMKKY | CRKDYAVQIH |
550:
ILKADKAGDW | WKFTVNIISV | YKQGTSRIRR | GDQSLWIRSR | DIACKCPKIK |
600:
PLKKYLLLGN | AEDSPDQSGI | VADKSSLVIQ | WRDTWARRLR | KFQQREKKGK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Chicken
Pig
ELISA Kit for Mouse Netrin-1
ELISA Kit for Mouse Netrin-1
ELISA Kit for Mouse Netrin-1
ELISA Kit for Mouse Netrin-1
ELISA Kit for Mouse Netrin-1
CLIA Kit for Mouse Netrin-1
CLIA Kit for Mouse Netrin-1
CLIA Kit for Mouse Netrin-1
CLIA Kit for Mouse Netrin-1
CLIA Kit for Mouse Netrin-1
Polyclonal Antibody for Mouse Netrin-1
Polyclonal Antibody for Mouse Netrin-1
Polyclonal Antibody for Mouse Netrin-1
Polyclonal Antibody for Mouse Netrin-1
Polyclonal Antibody for Mouse Netrin-1
Monoclonal Antibody for Mouse Netrin-1
Monoclonal Antibody for Mouse Netrin-1
Monoclonal Antibody for Mouse Netrin-1
Monoclonal Antibody for Mouse Netrin-1
Monoclonal Antibody for Mouse Netrin-1
Protein for Mouse Netrin-1
Protein for Mouse Netrin-1
Protein for Mouse Netrin-1
Protein for Mouse Netrin-1
Protein for Mouse Netrin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
C Jayakumar, R Mohamed, PV Ranganathan, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
tissue :
Embryonic brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
3.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 352-398;SUBCELLULAR LOCATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DSCAM