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Index > Protein center > NFKB2(Gene name) > Human
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  • NFKB2 (Gene name),
  • Nuclear factor NF-kappa-B p100 subunit (Protein name ),  NFKB2_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    NFKB2(LYT10);
    Protein name:
    Nuclear factor NF-kappa-B p100 subunit;
    Alternative:
    H2TF1;DNA-binding factor KBF2;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2;Lymphocyte translocation chromosome 10 protein;Oncogene Lyt-10(Lyt10);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the NF-kappa-B RelB-p52 complex. Homodimer; component of the NF-kappa-B p52-p52 complex. Component of the NF-kappa-B p65-p52 complex. Component of the NF-kappa-B p52-c-Rel complex. NFKB2/p52 interacts with NFKBIE. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Directly interacts with MEN1.
    Function:
    NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. In a non-canonical activation pathway, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. The NF-kappa-B heterodimeric RelB-p52 complex is a transcriptional activator. The NF-kappa-B p52-p52 homodimer is a transcriptional repressor. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. p52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. p52 and p100 are respectively the minor and major form; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65.
    Subcellular Location:
    Nucleus Cytoplasm Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor.
    Protein Attributes:
    Sequence length:
    900
    Sequence:
    50:
    MESCYNPGLD | GIIEYDDFKL | NSSIVEPKEP | APETADGPYL | VIVEQPKQRG | 
    100:
    FRFRYGCEGP | SHGGLPGASS | EKGRKTYPTV | KICNYEGPAK | IEVDLVTHSD | 
    150:
    PPRAHAHSLV | GKQCSELGIC | AVSVGPKDMT | AQFNNLGVLH | VTKKNMMGTM | 
    200:
    IQKLQRQRLR | SRPQGLTEAE | QRELEQEAKE | LKKVMDLSIV | RLRFSAFLRA | 
    250:
    SDGSFSLPLK | PVISQPIHDS | KSPGASNLKI | SRMDKTAGSV | RGGDEVYLLC | 
    300:
    DKVQKDDIEV | RFYEDDENGW | QAFGDFSPTD | VHKQYAIVFR | TPPYHKMKIE | 
    350:
    RPVTVFLQLK | RKRGGDVSDS | KQFTYYPLVE | DKEEVQRKRR | KALPTFSQPF | 
    400:
    GGGSHMGGGS | GGAAGGYGGA | GGGGSLGFFP | SSLAYSPYQS | GAGPMGCYPG | 
    450:
    GGGGAQMAAT | VPSRDSGEEA | AEPSAPSRTP | QCEPQAPEML | QRAREYNARL | 
    500:
    FGLAQRSARA | LLDYGVTADA | RALLAGQRHL | LTAQDENGDT | PLHLAIIHGQ | 
    550:
    TSVIEQIVYV | IHHAQDLGVV | NLTNHLHQTP | LHLAVITGQT | SVVSFLLRVG | 
    600:
    ADPALLDRHG | DSAMHLALRA | GAGAPELLRA | LLQSGAPAVP | QLLHMPDFEG | 
    650:
    LYPVHLAVRA | RSPECLDLLV | DSGAEVEATE | RQGGRTALHL | ATEMEELGLV | 
    700:
    THLVTKLRAN | VNARTFAGNT | PLHLAAGLGY | PTLTRLLLKA | GADIHAENEE | 
    750:
    PLCPLPSPPT | SDSDSDSEGP | EKDTRSSFRG | HTPLDLTCST | KVKTLLLNAA | 
    800:
    QNTMEPPLTP | PSPAGPGLSL | GDTALQNLEQ | LLDGPEAQGS | WAELAERLGL | 
    850:
    RSLVDTYRQT | TSPSGSLLRS | YELAGGDLAG | LLEALSDMGL | EEGVRLLRGP | 
    900:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    String:
    UniGene:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Nuclear factor NF-kappa-B p100 subunit
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    E9393m
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    96T
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    ELISA Kit for Human Nuclear factor NF-kappa-B p100 subunit
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    ELISA Kit for Human Nuclear factor NF-kappa-B p100 subunit
    Cat.:
    E9393h
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    Packing:
    96T
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    CLIA Kit for Human Nuclear factor NF-kappa-B p100 subunit
    Cat.:
    U9393h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Nuclear factor NF-kappa-B p100 subunit
    MSDS:
    Please sign in first.
    CLIA Kit for Human Nuclear factor NF-kappa-B p100 subunit
    Cat.:
    U9393m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Nuclear factor NF-kappa-B p100 subunit
    Cat.:
    P9393Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Nuclear factor NF-kappa-B p100 subunit
    Cat.:
    P9393Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Nuclear factor NF-kappa-B p100 subunit
    Monoclonal Antibody for Human Nuclear factor NF-kappa-B p100 subunit
    Monoclonal Antibody for Human Nuclear factor NF-kappa-B p100 subunit
    Monoclonal Antibody for Human Nuclear factor NF-kappa-B p100 subunit
    Protein for Human Nuclear factor NF-kappa-B p100 subunit
    Protein for Human Nuclear factor NF-kappa-B p100 subunit
    Protein for Human Nuclear factor NF-kappa-B p100 subunit

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    References
    1. 1.
      "Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65."
      Schmid R.M. , Perkins N.D. , Duckett C.S. , Andrews P.C. , Nabel G.J.
      Nature352:733-736(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4)
      tissue: Leukemia.
    2. 2.
      "A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site."
      Bours V. , Burd P.R. , Brown K. , Villalobos J. , Park S. , Ryseck R.P. , Bravo R. , Kelly K. , Siebenlist U.
      Mol. Cell. Biol.12:685-695(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Rearrangement and altered expression of the NFKB-2 gene in human cutaneous T-lymphoma cells."
      Thakur S. , Lin H.C. , Tseng W.T. , Kumar S. , Bravo R. , Foss F. , Gelinas C. , Rabson A.B.
      Oncogene9:2335-2344(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHROMOSOMAL TRANSLOCATION;P80HT GENERATION
    4. 4.
      Rabson A.B.
      Submitted (2006-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Thymus.
    7. 7.
      NIEHS SNPs program
      Submitted (2004-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LYS-14; ARG-351 AND ARG-452
    8. 8.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Lymph.
    11. 11.
      "Transcriptional regulation of NF-kappa B2: evidence for kappa B-mediated positive and negative autoregulation."
      Liptay S. , Schmid R.M. , Nabel E.G. , Nabel G.J.
      Mol. Cell. Biol.14:7695-7703(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-220
    12. 12.
      "Purification of the major histocompatibility complex class I transcription factor H2TF1. The full-length product of the nfkb2 gene."
      Potter D.A. , Larson C.J. , Eckes P. , Schmid R.M. , Nabel G.J. , Verdine G.L. , Sharp P.A.
      J. Biol. Chem.268:18882-18890(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 459-470; 580-597 AND 636-647 (ISOFORM 1)
    13. 13.
      "The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers."
      Bours V. , Franzoso G. , Azarenko V. , Park S. , Kanno T. , Brown K. , Siebenlist U.
      Cell72:729-739(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH BCL3
    14. 14.
      "Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity."
      Dobrzanski P. , Ryseck R.P. , Bravo R.
      EMBO J.13:4608-4616(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE NF-KAPPA-B RELB-P52 COMPLEX
    15. 15.
      "Activation of multiple NF-kappa B/Rel DNA-binding complexes by tumor necrosis factor."
      Beg A.A. , Baldwin A.S. Jr.
      Oncogene9:1487-1492(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE NF-KAPPA-B P52-C-REL COMPLEX;IDENTIFICATION IN THE NF-KAPPA-B P65-P52 COMPLEX
    16. 16.
      "A new member of the IkappaB protein family, IkappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription."
      Li Z. , Nabel G.J.
      Mol. Cell. Biol.17:6184-6190(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NFKBIE
    17. 17.
      "The generation of nfkb2 p52: mechanism and efficiency."
      Heusch M. , Lin L. , Geleziunas R. , Greene W.C.
      Oncogene18:6201-6208(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COTRANSLATIONAL FOLDING/PROCESSING OF P100;GENERATION OF P52/P100
    18. 18.
      "Differential regulation of NF-kappaB2(p100) processing and control by amino-terminal sequences."
      Betts J.C. , Nabel G.J.
      Mol. Cell. Biol.16:6363-6371(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-713; SER-715 AND SER-717;MUTAGENESIS;DIMERIZATION;PROTEOLYTIC PROCESSING OF P100
    19. 19.
      "NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100."
      Xiao G. , Harhaj E.W. , Sun S.-C.
      Mol. Cell7:401-409(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-866 AND SER-870;MUTAGENESIS OF SER-866 AND SER-870;PROTEOLYTIC PROCESSING OF P100
    20. 20.
      "B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50."
      Neri A. , Chang C.C. , Lombardi L. , Salina M. , Corradini P. , Maiolo A.T. , Chaganti R.S. , Dalla-Favera R.
      Cell67:1075-1087(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH IGHA1
    21. 21.
      "Heterogeneous chromosomal aberrations generate 3' truncations of the NFKB2/lyt-10 gene in lymphoid malignancies."
      Migliazza A. , Lombardi L. , Rocchi M. , Trecca D. , Chang C.-C. , Antonacci R. , Fracchiolla N.S. , Ciana P. , Maiolo A.T. , Neri A.
      Blood84:3850-3860(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL ABERRATIONS;GENERATION OF LB40 AND EB308
    22. 22.
      "Structural and functional characterization of the promoter regions of the NFKB2 gene."
      Lombardi L. , Ciana P. , Cappellini C. , Trecca D. , Guerrini L. , Migliazza A. , Maiolo A.T. , Neri A.
      Nucleic Acids Res.23:2328-2336(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF THE TWO PROMOTER REGIONS
    23. 23.
      "The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation."
      Heppner C. , Bilimoria K.Y. , Agarwal S.K. , Kester M. , Whitty L.J. , Guru S.C. , Chandrasekharappa S.C. , Collins F.S. , Spiegel A.M. , Marx S.J. , Burns A.L.
      Oncogene20:4917-4925(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MEN1
    24. 24.
      "Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase."
      Amir R.E. , Haecker H. , Karin M. , Ciechanover A.
      Oncogene23:2540-2547(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION AT LYS-855
    25. 25.
      "IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation."
      Song Y.J. , Jen K.Y. , Soni V. , Kieff E. , Cahir-McFarland E.
      Proc. Natl. Acad. Sci. U.S.A.103:2689-2694(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE NF-KAPPA-B P65-P52 COMPLEX
    26. 26.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-429;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    27. 27.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    28. 28.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    29. 29.
      "Germline mutations in NFKB2 implicate the noncanonical NF-kappaB pathway in the pathogenesis of common variable immunodeficiency."
      Chen K. , Coonrod E.M. , Kumanovics A. , Franks Z.F. , Durtschi J.D. , Margraf R.L. , Wu W. , Heikal N.M. , Augustine N.H. , Ridge P.G. , Hill H.R. , Jorde L.B. , Weyrich A.S. , Zimmerman G.A. , Gundlapalli A.V. , Bohnsack J.F. , Voelkerding K.V.
      Am. J. Hum. Genet.93:812-824(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN CVID10
    30. 30.
      "Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1-A resolution."
      Cramer P. , Larson C.J. , Verdine G.L. , Mueller C.W.
      EMBO J.16:7078-7090(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 37-327
    31. 31.
      "Solution structure of the death domain of nuclear factor NF-kappa-B p100."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2006-12) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 764-859
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