NGB ELISA Kit for Human(Homo sapiens) | EIAab.comNGB ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > NGB(Gene name) > Human

NGB (Gene name),

Neuroglobin (Protein name ), NGB_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

NGB;

Protein name:

Neuroglobin;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer. Homodimer and homotetramer; disulfide-linked.

Function:

Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes.

Subcellular Location:

Perikaryon

Protein Attributes:

Sequence length:

151

Sequence:

50:

100:

150:

151:

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Hs.274363

String:

Q9NPG2

SMR:

Q9NPG2

STRING:

9606.ENSP00000298352

MIM:

605304

KEGG:

hsa:58157

Pfam:

PF00042

Uniprot:

Q9NPG2

FOR

ELISA Kit for Human Neuroglobin

Cat.:

E0606h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human Neuroglobin

MSDS:

Please sign in first.

ELISA Kit for Human Neuroglobin

Cat.:

E0606d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human Neuroglobin

Cat.:

E0606p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human Neuroglobin

Cat.:

E0606b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human Neuroglobin

Cat.:

E0606r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human Neuroglobin

Cat.:

E0606m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Neuroglobin

Cat.:

U0606d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Neuroglobin

Cat.:

U0606p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Neuroglobin

MSDS:

Please sign in first.

CLIA Kit for Human Neuroglobin

Cat.:

U0606r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Neuroglobin

Cat.:

U0606h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Neuroglobin

Cat.:

U0606b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Neuroglobin

Cat.:

U0606m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Neuroglobin

Cat.:

P0606Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Neuroglobin

Cat.:

P0606Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Neuroglobin

Cat.:

P0606Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Neuroglobin

Monoclonal Antibody for Human Neuroglobin

Protein for Human Neuroglobin

Cat.:

R0606h

Price:

Please sign in first.

Packing:

1mg

Purity:

>90%

Protein for Human Neuroglobin

R&D Technical Data

Western blot- anti-NGB antibody

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤ 6.6%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤ 9.8%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of ACE into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	101	94-106
Plasma	99	92-104

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	94-106%	95-105%	93-103%	90-110%
EDTA plasma(n=5)	90-99%	93-107%	95-104%	96-108%
heparin plasma(n=5)	94-104%	96-110%	99-111%	93-108%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A vertebrate globin expressed in the brain."
Burmester T. , Weich B. , Reinhardt S. , Hankeln T.
Nature407:520-522(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];FUNCTION;TISSUE SPECIFICITY
tissue: Brain.
2.

"Full-length cDNA cloning of human neuroglobin and tissue expression of rat neuroglobin."
Zhang C.G. , Wang C.L. , Deng M.Y. , Li L. , Wang H.Y. , Fan M. , Xu W.L. , Meng F.W. , Qian L. , He F.C.
Biochem. Biophys. Res. Commun.290:1411-1419(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"The DNA sequence and analysis of human chromosome 14."
Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
5.

"Biochemical characterization and ligand binding properties of neuroglobin, a novel member of the globin family."
Dewilde S. , Kiger L. , Burmester T. , Hankeln T. , Baudin-Creuza V. , Aerts T. , Marden M.C. , Caubergs R. , Moens L.
J. Biol. Chem.276:38949-38955(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"Coupling of the heme and an internal disulfide bond in human neuroglobin."
Hamdane D. , Kiger L. , Dewilde S. , Green B.N. , Pesce A. , Uzan J. , Burmester T. , Hankeln T. , Bolognesi M. , Moens L. , Marden M.C.
Micron35:59-62(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BOND
7.

"Zebrafish neuroglobin is a cell-membrane-penetrating globin."
Watanabe S. , Wakasugi K.
Biochemistry47:5266-5270(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"A role for human neuroglobin in apoptosis."
Brittain T. , Skommer J. , Henty K. , Birch N. , Raychaudhuri S.
IUBMB Life62:878-885(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN APOPTOSIS
9.

"Human neuroglobin functions as a redox-regulated nitrite reductase."
Tiso M. , Tejero J. , Basu S. , Azarov I. , Wang X. , Simplaceanu V. , Frizzell S. , Jayaraman T. , Geary L. , Shapiro C. , Ho C. , Shiva S. , Kim-Shapiro D.B. , Gladwin M.T.
J. Biol. Chem.286:18277-18289(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISULFIDE BOND
10.

"14-3-3 binding and phosphorylation of neuroglobin during hypoxia modulate six-to-five heme pocket coordination and rate of nitrite reduction to nitric oxide."
Jayaraman T. , Tejero J. , Chen B.B. , Blood A.B. , Frizzell S. , Shapiro C. , Tiso M. , Hood B.L. , Wang X. , Zhao X. , Conrads T.P. , Mallampalli R.K. , Gladwin M.T.
J. Biol. Chem.286:42679-42689(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION DURING HYPOXIA;INTERACTION WITH 14-3-3
11.

"Human brain neuroglobin structure reveals a distinct mode of controlling oxygen affinity."
Pesce A. , Dewilde S. , Nardini M. , Moens L. , Ascenzi P. , Hankeln T. , Burmester T. , Bolognesi M.
Structure11:1087-1095(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) IN A HEXACOORDINATED FE(3+)-BOUND FORM

Product Feedback Wall

* Email:
*Comments: