Gene name:
TACR1 (NK1R;TAC1R) ;
Protein name:
Substance-P receptor (SPR) ;
Alternative:
Tachykinin receptor 1 ;NK-1 receptor (NK-1R) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with ARRB1.
Function:
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MDNVLPVDSD | LSPNISTNTS | EPNQFVQPAW | QIVLWAAAYT | VIVVTSVVGN |
100:
VVVMWIILAH | KRMRTVTNYF | LVNLAFAEAS | MAAFNTVVNF | TYAVHNEWYY |
150:
GLFYCKFHNF | FPIAAVFASI | YSMTAVAFDR | YMAIIHPLQP | RLSATATKVV |
200:
ICVIWVLALL | LAFPQGYYST | TETMPSRVVC | MIEWPEHPNK | IYEKVYHICV |
250:
TVLIYFLPLL | VIGYAYTVVG | ITLWASEIPG | DSSDRYHEQV | SAKRKVVKMM |
300:
IVVVCTFAIC | WLPFHIFFLL | PYINPDLYLK | KFIQQVYLAI | MWLAMSSTMY |
350:
NPIIYCCLND | RFRLGFKHAF | RCCPFISAGD | YEGLEMKSTR | YLQTQGSVYK |
400:
VSRLETTIST | VVGAHEEEPE | DGPKATPSSL | DLTSNCSSRS | DSKTMTESFS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Dog
Polyclonal Antibody for Human SPR
Polyclonal Antibody for Human SPR
Polyclonal Antibody for Human SPR
Polyclonal Antibody for Human SPR
Monoclonal Antibody for Human SPR
Monoclonal Antibody for Human SPR
Monoclonal Antibody for Human SPR
Monoclonal Antibody for Human SPR
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
John Moffett, Linley M Fray, and Nicole J Kubat
References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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tissue :
Brain .
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT HIS-192;CHARACTERIZATION OF VARIANT HIS-192