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Index > Protein center > NLGN4X(Gene name) > Human
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  • NLGN4X (Gene name),
  • Neuroligin-4, X-linked (Protein name ),  NLGNX_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    NLGN4X(UNQ365/PRO701;KIAA1260;NLGN4);
    Protein name:
    Neuroligin-4, X-linked(Neuroligin X);
    Alternative:
    HNLX;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with NRXN1 in a calcium-dependent manner. Interacts through its C-terminus with DLG4/PSD-95 third PDZ domain.
    Function:
    Putative neuronal cell surface protein involved in cell-cell-interactions.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Cell junction synapse postsynaptic cell membrane postsynaptic density
    Protein Attributes:
    Sequence length:
    816
    Sequence:
    50:
    MSRPQGLLWL | PLLFTPVCVM | LNSNVLLWLT | ALAIKFTLID | SQAQYPVVNT | 
    100:
    NYGKIRGLRT | PLPNEILGPV | EQYLGVPYAS | PPTGERRFQP | PEPPSSWTGI | 
    150:
    RNTTQFAAVC | PQHLDERSLL | HDMLPIWFTA | NLDTLMTYVQ | DQNEDCLYLN | 
    200:
    IYVPTEDDIH | DQNSKKPVMV | YIHGGSYMEG | TGNMIDGSIL | ASYGNVIVIT | 
    250:
    INYRLGILGF | LSTGDQAAKG | NYGLLDQIQA | LRWIEENVGA | FGGDPKRVTI | 
    300:
    FGSGAGASCV | SLLTLSHYSE | GLFQKAIIQS | GTALSSWAVN | YQPAKYTRIL | 
    350:
    ADKVGCNMLD | TTDMVECLRN | KNYKELIQQT | ITPATYHIAF | GPVIDGDVIP | 
    400:
    DDPQILMEQG | EFLNYDIMLG | VNQGEGLKFV | DGIVDNEDGV | TPNDFDFSVS | 
    450:
    NFVDNLYGYP | EGKDTLRETI | KFMYTDWADK | ENPETRRKTL | VALFTDHQWV | 
    500:
    APAVATADLH | AQYGSPTYFY | AFYHHCQSEM | KPSWADSAHG | DEVPYVFGIP | 
    550:
    MIGPTELFSC | NFSKNDVMLS | AVVMTYWTNF | AKTGDPNQPV | PQDTKFIHTK | 
    600:
    PNRFEEVAWS | KYNPKDQLYL | HIGLKPRVRD | HYRATKVAFW | LELVPHLHNL | 
    650:
    NEIFQYVSTT | TKVPPPDMTS | FPYGTRRSPA | KIWPTTKRPA | ITPANNPKHS | 
    700:
    KDPHKTGPED | TTVLIETKRD | YSTELSVTIA | VGASLLFLNI | LAFAALYYKK | 
    750:
    DKRRHETHRR | PSPQRNTTND | IAHIQNEEIM | SLQMKQLEHD | HECESLQAHD | 
    800:
    TLRLTCPPDY | TLTLRRSPDD | IPLMTPNTIT | MIPNTLTGMQ | PLHTFNTFSG | 
    816:
    GQNSTNLPHG | HSTTRV
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    String:
    SMR:
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Neuroligin X
    Cat.:
    E6841h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Neuroligin X
    Cat.:
    U6841h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Neuroligin X
    Cat.:
    P6841Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Neuroligin X
    Protein for Human Neuroligin X

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);DISEASE
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Kikuno R. , Hirosawa M. , Nomura N. , Ohara O.
      DNA Res.6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
    4. 4.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4-816 (ISOFORM 2)
    5. 5.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 42-56
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLG4
    7. 7.
      "Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression."
      Bolliger M.F. , Frei K. , Winterhalter K.H. , Gloor S.M.
      Biochem. J.356:581-588(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLG4;TISSUE SPECIFICITY
    8. 8.
      "X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family."
      Laumonnier F. , Bonnet-Brilhault F. , Gomot M. , Blanc R. , David A. , Moizard M.-P. , Raynaud M. , Ronce N. , Lemonnier E. , Calvas P. , Laudier B. , Chelly J. , Fryns J.-P. , Ropers H.-H. , Hamel B.C.J. , Andres C. , Barthelemy C. , Moraine C. , more...
      Am. J. Hum. Genet.74:552-557(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ATSX2 AND ASPGX2
    9. 9.
      "Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion."
      Fabrichny I.P. , Leone P. , Sulzenbacher G. , Comoletti D. , Miller M.T. , Taylor P. , Bourne Y. , Marchot P.
      Neuron56:979-991(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 44-619 ALONE AND IN COMPLEX WITH RAT NRXN1;GLYCOSYLATION AT ASN-102 AND ASN-511;SUBUNIT;DISULFIDE BONDS
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] SER-214
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