NLGN4X ELISA Kit for Human(Homo sapiens) | EIAab.comNLGN4X ELISA Kit for Human(Homo sapiens)

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NLGN4X (Gene name),

Neuroligin-4, X-linked (Protein name ), NLGNX_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NLGN4X(UNQ365/PRO701;KIAA1260;NLGN4);

Protein name:

Neuroligin-4, X-linked(Neuroligin X);

Alternative:

HNLX;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Interacts with NRXN1 in a calcium-dependent manner. Interacts through its C-terminus with DLG4/PSD-95 third PDZ domain.

Function:

Putative neuronal cell surface protein involved in cell-cell-interactions.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Cell junction synapse postsynaptic cell membrane postsynaptic density

Protein Attributes:

Sequence length:

816

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

816:

GQNSTNLPHG | HSTTRV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000275857

MIM:

300427

String:

Q8N0W4

SMR:

Q8N0W4

Pfam:

PF00135

UniGene:

Hs.21107

KEGG:

hsa:57502

Uniprot:

Q8N0W4

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ELISA Kit for Human Neuroligin X

Cat.:

E6841h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Neuroligin X

Cat.:

U6841h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Neuroligin X

Cat.:

P6841Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Neuroligin X

Protein for Human Neuroligin X

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism."
Jamain S. , Quach H. , Betancur C. , Rastam M. , Colineaux C. , Gillberg I.C. , Soderstrom H. , Giros B. , Leboyer M. , Gillberg C. , Bourgeron T. , Nyden A. , Philippe A. , Cohen D. , Chabane N. , Mouren-Simeoni M.C. , Brice A. , Sponheim E. , more...
Nat. Genet.34:27-29(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);DISEASE
2.

"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T. , Ishikawa K. , Kikuno R. , Hirosawa M. , Nomura N. , Ohara O.
DNA Res.6:337-345(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Lung.
4.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4-816 (ISOFORM 2)
5.

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z. , Henzel W.J.
Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 42-56
6.

"Binding of neuroligins to PSD-95."
Irie M. , Hata Y. , Takeuchi M. , Ichtchenko K. , Toyoda A. , Hirao K. , Takai Y. , Rosahl T.W. , Suedhof T.C.
Science277:1511-1515(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLG4
7.

"Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression."
Bolliger M.F. , Frei K. , Winterhalter K.H. , Gloor S.M.
Biochem. J.356:581-588(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLG4;TISSUE SPECIFICITY
8.

"X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family."
Laumonnier F. , Bonnet-Brilhault F. , Gomot M. , Blanc R. , David A. , Moizard M.-P. , Raynaud M. , Ronce N. , Lemonnier E. , Calvas P. , Laudier B. , Chelly J. , Fryns J.-P. , Ropers H.-H. , Hamel B.C.J. , Andres C. , Barthelemy C. , Moraine C. , more...
Am. J. Hum. Genet.74:552-557(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ATSX2 AND ASPGX2
9.

"Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion."
Fabrichny I.P. , Leone P. , Sulzenbacher G. , Comoletti D. , Miller M.T. , Taylor P. , Bourne Y. , Marchot P.
Neuron56:979-991(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 44-619 ALONE AND IN COMPLEX WITH RAT NRXN1;GLYCOSYLATION AT ASN-102 AND ASN-511;SUBUNIT;DISULFIDE BONDS
10.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] SER-214

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