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Index > Protein center > NPFFR2(Gene name) > Human
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  • NPFFR2 (Gene name),
  • Neuropeptide FF receptor 2 (Protein name ),  NPFF2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    NPFFR2(GPR74;NPFF2;NPGPR);
    Protein name:
    Neuropeptide FF receptor 2;
    Alternative:
    G-protein coupled receptor HLWAR77;G-protein coupled receptor 74;Neuropeptide G-protein coupled receptor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    522
    Sequence:
    50:
    MNSFFGTPAA | SWCLLESDVS | SAPDKEAGRE | RRALSVQQRG | GPAWSGSLEW | 
    100:
    SRQSAGDRRR | LGLSRQTAKS | SWSRSRDRTC | CCRRAWWILV | PAADRARRER | 
    150:
    FIMNEKWDTN | SSENWHPIWN | VNDTKHHLYS | DINITYVNYY | LHQPQVAAIF | 
    200:
    IISYFLIFFL | CMMGNTVVCF | IVMRNKHMHT | VTNLFILNLA | ISDLLVGIFC | 
    250:
    MPITLLDNII | AGWPFGNTMC | KISGLVQGIS | VAASVFTLVA | IAVDRFQCVV | 
    300:
    YPFKPKLTIK | TAFVIIMIIW | VLAITIMSPS | AVMLHVQEEK | YYRVRLNSQN | 
    350:
    KTSPVYWCRE | DWPNQEMRKI | YTTVLFANIY | LAPLSLIVIM | YGRIGISLFR | 
    400:
    AAVPHTGRKN | QEQWHVVSRK | KQKIIKMLLI | VALLFILSWL | PLWTLMMLSD | 
    450:
    YADLSPNELQ | IINIYIYPFA | HWLAFGNSSV | NPIIYGFFNE | NFRRGFQEAF | 
    500:
    QLQLCQKRAK | PMEAYALKAK | SHVLINTSNQ | LVQESTFQNP | HGETLLYRKS | 
    522:
    AEKPQQELVM | EELKETTNSS | EI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    Pfam:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Neuropeptide FF receptor 2
    Cat.:
    E12270h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Neuropeptide FF receptor 2
    Cat.:
    E12270r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Neuropeptide FF receptor 2
    Cat.:
    E12270m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Neuropeptide FF receptor 2
    Cat.:
    U12270h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Neuropeptide FF receptor 2
    Cat.:
    U12270m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Neuropeptide FF receptor 2
    Cat.:
    U12270r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Neuropeptide FF receptor 2
    Cat.:
    P12270Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Neuropeptide FF receptor 2
    Polyclonal Antibody for Human Neuropeptide FF receptor 2
    Monoclonal Antibody for Human Neuropeptide FF receptor 2
    Monoclonal Antibody for Human Neuropeptide FF receptor 2
    Monoclonal Antibody for Human Neuropeptide FF receptor 2
    Protein for Human Neuropeptide FF receptor 2
    Protein for Human Neuropeptide FF receptor 2
    Protein for Human Neuropeptide FF receptor 2

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    Precision
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    Linearity
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    References
    1. 1.
      "Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta."
      Cikos S. , Gregor P. , Koppel J.
      Biochem. Biophys. Res. Commun.256:352-356(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Fetus.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);CHARACTERIZATION
      tissue: Brain.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);CHARACTERIZATION
      tissue: Spinal cord.
    4. 4.
      "Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family."
      Parker R.M.C. , Copeland N.G. , Eyre H.J. , Liu M. , Gilbert D.J. , Crawford J. , Couzens M. , Sutherland G.R. , Jenkins N.A. , Herzog H.
      Brain Res. Mol. Brain Res.77:199-208(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
    5. 5.
      "Identification and characterization of two cognate receptors for mammalian FMRFamide-like neuropeptides."
      Liu Q. , Guan X.-M. , McDonald T.P. , Jiang Q. , Zeng Z. , Marlene J. , Williams D.L. Jr. , Hong Y. , Figueroa D. , Clements M.K. , Mallee J. , Wang R. , Evans J. , Gould R. , Austin C.P.
      Submitted (2000-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    6. 6.
      "Cloning and characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus."
      Laemmle B.S. , Schindler M. , Beilmann M. , Hamilton B.S. , Doods H.N. , Wieland H.A.
      Submitted (2001-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4)
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