Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > NR1I3(Gene name) > Human
  • Add your favorite
  • NR1I3 (Gene name),
  • Nuclear receptor subfamily 1 group I member 3 (Protein name ),  NR1I3_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    NR1I3(CAR);
    Protein name:
    Nuclear receptor subfamily 1 group I member 3;
    Alternative:
    Constitutive androstane receptor(CAR);Constitutive activator of retinoid response(Constitutive active response);Orphan nuclear receptor MB67;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of NR1I3 and RXR. Interacts with PSMC4.
    Function:
    Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    352
    Sequence:
    50:
    MASREDELRN | CVVCGDQATG | YHFNALTCEG | CKGFFRRTVS | KSIGPTCPFA | 
    100:
    GSCEVSKTQR | RHCPACRLQK | CLDAGMRKDM | ILSAEALALR | RAKQAQRRAQ | 
    150:
    QTPVQLSKEQ | EELIRTLLGA | HTRHMGTMFE | QFVQFRPPAH | LFIHHQPLPT | 
    200:
    LAPVLPLVTH | FADINTFMVL | QVIKFTKDLP | VFRSLPIEDQ | ISLLKGAAVE | 
    250:
    ICHIVLNTTF | CLQTQNFLCG | PLRYTIEDGA | RVSPTVGFQV | EFLELLFHFH | 
    300:
    GTLRKLQLQE | PEYVLLAAMA | LFSPDRPGVT | QRDEIDQLQE | EMALTLQSYI | 
    350:
    KGQQRRPRDR | FLYAKLLGLL | AELRSINEAY | GYQIQHIQGL | SAMMPLLQEI | 
    352:
    CS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    Pfam:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    E2157h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    E2157m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    E2157r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    U2157m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    U2157h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    U2157r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    P2157Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    P2157Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Nuclear receptor subfamily 1 group I member 3
    Cat.:
    P2157Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Nuclear receptor subfamily 1 group I member 3
    Monoclonal Antibody for Human Nuclear receptor subfamily 1 group I member 3
    Monoclonal Antibody for Human Nuclear receptor subfamily 1 group I member 3
    Protein for Human Nuclear receptor subfamily 1 group I member 3
    Protein for Human Nuclear receptor subfamily 1 group I member 3
    Protein for Human Nuclear receptor subfamily 1 group I member 3

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements."
      Baes M. , Gulick T. , Choi H.S. , Martinoli M.G. , Simha D. , Moore D.D.
      Mol. Cell. Biol.14:1544-1552(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Liver.
    2. 2.
      "Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences."
      Lamba J.K. , Lamba V. , Yasuda K. , Lin Y.S. , Assem M. , Thompson E. , Strom S. , Schuetz E.G.
      J. Pharmacol. Exp. Ther.311:811-821(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 4; 5; 6 AND 7);NUCLEOTIDE SEQUENCE [MRNA] OF 1-288 (ISOFORM 9);NUCLEOTIDE SEQUENCE [MRNA] OF 1-293 (ISOFORM 10);NUCLEOTIDE SEQUENCE [MRNA] OF 1-297 (ISOFORM 11);NUCLEOTIDE SEQUENCE [MRNA] OF 1-321 (ISOFORM 12);NUCLEOTIDE SEQUENCE [MRNA] OF 1-322 (ISOFORM 13);NUCLEOTIDE SEQUENCE [MRNA] OF 1-279 (ISOFORM 14);NUCLEOTIDE SEQUENCE [MRNA] OF 1-266 (ISOFORM 15);ALTERNATIVE SPLICING
    3. 3.
      Zhou G. , Nong W. , Li H. , Ke R. , Shen C. , Zhong G. , Zheng Z. , Liang M. , Huang B. , Lin L. , Yang S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 8)
    4. 4.
      "Isolation of cDNA coding for multiple human nuclear receptor clones."
      Kaighin V.A. , Martin A.L. , Aronstam R.S.
      Submitted (2010-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 3 AND 7)
      tissue: Eye.
      tissue: Small intestine.
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 7)
    8. 8.
      "A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily."
      Choi H.S. , Seol W. , Moore D.D.
      J. Steroid Biochem. Mol. Biol.56:23-30(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PSMC4
    9. 9.
      "Cytoplasmic accumulation of the nuclear receptor CAR by a tetratricopeptide repeat protein in HepG2 cells."
      Kobayashi K. , Sueyoshi T. , Inoue K. , Moore R. , Negishi M.
      Mol. Pharmacol.64:1069-1075(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DNAJC7;SUBCELLULAR LOCATION
    10. 10.
      "Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3)."
      Mutoh S. , Osabe M. , Inoue K. , Moore R. , Pedersen L. , Perera L. , Rebolloso Y. , Sueyoshi T. , Negishi M.
      J. Biol. Chem.284:34785-34792(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-38;SUBCELLULAR LOCATION
    11. 11.
      "A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer."
      Xu R.X. , Lambert M.H. , Wisely B.B. , Warren E.N. , Weinert E.E. , Waitt G.M. , Williams J.D. , Collins J.L. , Moore L.B. , Willson T.M. , Moore J.T.
      Mol. Cell16:919-928(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 103-352
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLY-133
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5
    Top Searches
    Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Tumor necrosis Alpha Asprosin TRAP1A
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter