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Index > Protein center > NTF3(Gene name) > Human
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  • NTF3 (Gene name),
  • Neurotrophin-3 (Protein name ),  NTF3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NTF3;
    Protein name:
    Neurotrophin-3(NT-3);
    Alternative:
    Nerve growth factor 2(NGF-2);HDNF;Neurotrophic factor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Seems to promotes the survival of visceral and proprioceptive sensory neurons.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    257
    Sequence:
    50:
    MSILFYVIFL | AYLRGIQGNN | MDQRSLPEDS | LNSLIIKLIQ | ADILKNKLSK | 
    100:
    QMVDVKENYQ | STLPKAEAPR | EPERGGPAKS | AFQPVIAMDT | ELLRQQRRYN | 
    150:
    SPRVLLSDST | PLEPPPLYLM | EDYVGSPVVA | NRTSRRKRYA | EHKSHRGEYS | 
    200:
    VCDSESLWVT | DKSSAIDIRG | HQVTVLGEIK | TGNSPVKQYF | YETRCKEARP | 
    250:
    VKNGCRGIDD | KHWNSQCKTS | QTYVRALTSE | NNKLVGWRWI | RIDTSCVCAL | 
    257:
    SRKIGRT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    MIM:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human NT-3
    Cat.:
    E0106r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human NT-3
    Cat.:
    E0106h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human NT-3
    Cat.:
    E0106m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human NT-3
    Cat.:
    E0106b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human NT-3
    Cat.:
    E0106p
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human NT-3
    Cat.:
    E0106c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NT-3
    Cat.:
    U0106h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NT-3
    Cat.:
    U0106b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NT-3
    Cat.:
    U0106p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NT-3
    Cat.:
    U0106m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NT-3
    Cat.:
    U0106r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Human NT-3
    Cat.:
    U0106c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human NT-3
    Cat.:
    P0106Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NT-3
    Polyclonal Antibody for Human NT-3
    Cat.:
    P0106Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NT-3
    Polyclonal Antibody for Human NT-3
    Cat.:
    P0106Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NT-3
    Monoclonal Antibody for Human NT-3
    Monoclonal Antibody for Human NT-3
    Monoclonal Antibody for Human NT-3
    Monoclonal Antibody for Human NT-3
    Monoclonal Antibody for Human NT-3
    Monoclonal Antibody for Human NT-3
    Protein for Human NT-3
    Protein for Human NT-3
    Cat.:
    R0106h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human NT-3
    Cat.:
    R0106m
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human NT-3
    Protein for Human NT-3
    Protein for Human NT-3

    R&D Technical Data
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        12% SDS-PAGE Analysis

     

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 5.9%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 8.6%

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    Recovery
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    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    95-103

    Plasma

    101

    96-106

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    89-101%

    90-103%

    95-106%

    96-109%

    EDTA plasma(n=5)

    91-97%

    92-105%

    93-99%

    91-104%

    heparin plasma(n=5)

    93-101%

     

    94-106%

    101-108%

    91-104%

     

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    References
    1. 1.
      "Cloning and expression of a cDNA encoding a novel human neurotrophic factor."
      Kaisho Y. , Yoshimura K. , Nakahama K.
      FEBS Lett.266:187-191(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Primary structure and biological activity of a novel human neurotrophic factor."
      Rosenthal A. , Goeddel D.V. , Nguyen T. , Lewis M. , Shih A. , Laramee G.R. , Nikolics K. , Winslow J.W.
      Neuron4:767-773(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
    3. 3.
      "Molecular cloning of a human gene that is a member of the nerve growth factor family."
      Jones K.R. , Reichardt L.F.
      Proc. Natl. Acad. Sci. U.S.A.87:8060-8064(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations."
      Maisonpierre P.C. , le Beau M.M. , Espinosa R. III , Ip N.Y. , Belluscio L. , de la Monte S.M. , Squinto S. , Furth M.E. , Yancopoulos G.D.
      Genomics10:558-568(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Cerebellum.
    6. 6.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    9. 9.
      "Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary."
      Hallboeoek F. , Ibanez C.F. , Persson H.
      Neuron6:845-858(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 194-236
      tissue: Leukocyte.
    10. 10.
      "Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer."
      Robinson R.C. , Radziejewski C. , Stuart D.I. , Jones E.Y.
      Biochemistry34:4139-4146(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS)
    11. 11.
      "Association of neurotrophin-3 gene variant with severe forms of schizophrenia."
      Hattori M. , Nanko S.
      Biochem. Biophys. Res. Commun.209:513-518(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLU-76
    12. 12.
      "Failure to find associations of the CA repeat polymorphism in the first intron and the Gly-63/Glu-63 polymorphism of the neurotrophin-3 gene with schizophrenia."
      Arinami T. , Takekoshi K. , Itokawa M. , Hamaguchi H. , Toru M.
      Psychiatr. Genet.6:13-15(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLU-76
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