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Index > Protein center > O3FAR1(Gene name) > Human
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  • O3FAR1 (Gene name),
  • Omega-3 fatty acid receptor 1 (Protein name ),  O3FA1_HUMAN from NCBI database.
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  • Gene name:
    O3FAR1(GPR120;GPR129;PGR4);
    Protein name:
    Omega-3 fatty acid receptor 1;
    Alternative:
    G-protein coupled receptor 129;G-protein coupled receptor 120;G-protein coupled receptor PGR4;G-protein coupled receptor GT01;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with ARRB2 following docosahexaenoic acid (DHA) stimulation.
    Function:
    Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Colocalized with ARRB2 following DHA treatment.
    Protein Attributes:
    Sequence length:
    377
    Sequence:
    50:
    MSPECARAAG | DAPLRSLEQA | NRTRFPFFSD | VKGDHRLVLA | AVETTVLVLI | 
    100:
    FAVSLLGNVC | ALVLVARRRR | RGATACLVLN | LFCADLLFIS | AIPLVLAVRW | 
    150:
    TEAWLLGPVA | CHLLFYVMTL | SGSVTILTLA | AVSLERMVCI | VHLQRGVRGP | 
    200:
    GRRARAVLLA | LIWGYSAVAA | LPLCVFFRVV | PQRLPGADQE | ISICTLIWPT | 
    250:
    IPGEISWDVS | FVTLNFLVPG | LVIVISYSKI | LQTSEHLLDA | RAVVTHSEIT | 
    300:
    KASRKRLTVS | LAYSESHQIR | VSQQDFRLFR | TLFLLMVSFF | IMWSPIIITI | 
    350:
    LLILIQNFKQ | DLVIWPSLFF | WVVAFTFANS | ALNPILYNMT | LCRNEWKKIF | 
    377:
    CCFWFPEKGA | ILTDTSVKRN | DLSIISG
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Omega-3 fatty acid receptor 1
    Cat.:
    E12801m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Omega-3 fatty acid receptor 1
    Cat.:
    E12801h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Omega-3 fatty acid receptor 1
    Cat.:
    E12801r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Omega-3 fatty acid receptor 1
    Cat.:
    U12801h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Omega-3 fatty acid receptor 1
    Cat.:
    U12801m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Omega-3 fatty acid receptor 1
    Cat.:
    U12801r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Omega-3 fatty acid receptor 1
    Cat.:
    P12801Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Omega-3 fatty acid receptor 1
    Polyclonal Antibody for Human Omega-3 fatty acid receptor 1
    Monoclonal Antibody for Human Omega-3 fatty acid receptor 1
    Monoclonal Antibody for Human Omega-3 fatty acid receptor 1
    Monoclonal Antibody for Human Omega-3 fatty acid receptor 1
    Protein for Human Omega-3 fatty acid receptor 1
    Protein for Human Omega-3 fatty acid receptor 1
    Protein for Human Omega-3 fatty acid receptor 1

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