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Index > Protein center > OGDH(Gene name) > Human
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  • OGDH (Gene name),
  • 2-oxoglutarate dehydrogenase, mitochondrial (Protein name ),  ODO1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    OGDH;
    Protein name:
    2-oxoglutarate dehydrogenase, mitochondrial;
    Alternative:
    Alpha-ketoglutarate dehydrogenase;2-oxoglutarate dehydrogenase complex component E1(OGDC-E1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
    Subcellular Location:
    Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    1023
    Sequence:
    50:
    MFHLRTCAAK | LRPLTASQTV | KTFSQNRPAA | ARTFQQIRCY | SAPVAAEPFL | 
    100:
    SGTSSNYVEE | MYCAWLENPK | SVHKSWDIFF | RNTNAGAPPG | TAYQSPLPLS | 
    150:
    RGSLAAVAHA | QSLVEAQPNV | DKLVEDHLAV | QSLIRAYQIR | GHHVAQLDPL | 
    200:
    GILDADLDSS | VPADIISSTD | KLGFYGLDES | DLDKVFHLPT | TTFIGGQESA | 
    250:
    LPLREIIRRL | EMAYCQHIGV | EFMFINDLEQ | CQWIRQKFET | PGIMQFTNEE | 
    300:
    KRTLLARLVR | STRFEEFLQR | KWSSEKRFGL | EGCEVLIPAL | KTIIDKSSEN | 
    350:
    GVDYVIMGMP | HRGRLNVLAN | VIRKELEQIF | CQFDSKLEAA | DEGSGDVKYH | 
    400:
    LGMYHRRINR | VTDRNITLSL | VANPSHLEAA | DPVVMGKTKA | EQFYCGDTEG | 
    450:
    KKVMSILLHG | DAAFAGQGIV | YETFHLSDLP | SYTTHGTVHV | VVNNQIGFTT | 
    500:
    DPRMARSSPY | PTDVARVVNA | PIFHVNSDDP | EAVMYVCKVA | AEWRSTFHKD | 
    550:
    VVVDLVCYRR | NGHNEMDEPM | FTQPLMYKQI | RKQKPVLQKY | AELLVSQGVV | 
    600:
    NQPEYEEEIS | KYDKICEEAF | ARSKDEKILH | IKHWLDSPWP | GFFTLDGQPR | 
    650:
    SMSCPSTGLT | EDILTHIGNV | ASSVPVENFT | IHGGLSRILK | TRGEMVKNRT | 
    700:
    VDWALAEYMA | FGSLLKEGIH | IRLSGQDVER | GTFSHRHHVL | HDQNVDKRTC | 
    750:
    IPMNHLWPNQ | APYTVCNSSL | SEYGVLGFEL | GFAMASPNAL | VLWEAQFGDF | 
    800:
    HNTAQCIIDQ | FICPGQAKWV | RQNGIVLLLP | HGMEGMGPEH | SSARPERFLQ | 
    850:
    MCNDDPDVLP | DLKEANFDIN | QLYDCNWVVV | NCSTPGNFFH | VLRRQILLPF | 
    900:
    RKPLIIFTPK | SLLRHPEARS | SFDEMLPGTH | FQRVIPEDGP | AAQNPENVKR | 
    950:
    LLFCTGKVYY | DLTRERKARD | MVGQVAITRI | EQLSPFPFDL | LLKEVQKYPN | 
    1000:
    AELAWCQEEH | KNQGYYDYVK | PRLRTTISRA | KPVWYAGRDP | AAAPATGNKK | 
    1023:
    THLTELQRLL | DTAFDLDVFK | NFS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    E1923r
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    MSDS:
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    96T
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    ELISA Kit for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    E1923h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    E1923m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    E1923b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    U1923b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    U1923h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    U1923m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    U1923r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    P1923Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Polyclonal Antibody for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    P1923Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Cat.:
    P1923Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Monoclonal Antibody for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Monoclonal Antibody for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Monoclonal Antibody for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Protein for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Protein for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Protein for Human 2-oxoglutarate dehydrogenase, mitochondrial
    Protein for Human 2-oxoglutarate dehydrogenase, mitochondrial

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and nucleotide sequence of the cDNA encoding human 2-oxoglutarate dehydrogenase (lipoamide)."
      Koike K. , Urata Y. , Goto S.
      Proc. Natl. Acad. Sci. U.S.A.89:1963-1967(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Liver.
    2. 2.
      "The gene encoding human 2-oxoglutarate dehydrogenase: structural organization and mapping to chromosome 7p13-p14."
      Koike K.
      Gene159:261-266(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];SEQUENCE REVISION
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Trachea.
    4. 4.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      tissue: Bone marrow.
      tissue: Muscle.
    7. 7.
      "Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry."
      Denis N.J. , Vasilescu J. , Lambert J.-P. , Smith J.C. , Figeys D.
      Proteomics7:868-874(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-534
      tissue: Mammary cancer.
    8. 8.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-970;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site."
      Armstrong C.T. , Anderson J.L. , Denton R.M.
      Biochem. J.459:369-381(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;CALCIUM-BINDING SITES;MUTAGENESIS OF ASP-154
    11. 11.
      "Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors."
      Jones L.L. , Colf L.A. , Bankovich A.J. , Stone J.D. , Gao Y.G. , Chan C.M. , Huang R.H. , Garcia K.C. , Kranz D.M.
      Biochemistry47:12398-12408(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 932-940 IN COMPLEX WITH H-2 CLASS I HISTOCOMPATIBILITY COMPLEX
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