Pdha1 ELISA Kit for Mouse(Mus musculus) | EIAab.comPdha1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Pdha1(Gene name) > Mouse

Pdha1 (Gene name),

Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (Protein name ), ODPA_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Pdha1(Pdha-1);

Protein name:

Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;

Alternative:

PDHE1-A type I;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Tetramer of 2 alpha and 2 beta subunits.

Function:

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

Subcellular Location:

Mitochondrion matrix

Protein Attributes:

Sequence length:

390

Sequence:

50:

100:

150:

200:

250:

300:

350:

390:

QFATADPEPP | LEELGYHIYS | SDPPFEVRGA | NQWIKFKSVS |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P35486

SMR:

P35486

Pfam:

PF00676

STRING:

10090.ENSMUSP00000033662

KEGG:

mmu:18597

UniGene:

Mm.34775

Uniprot:

P35486

FOR

ELISA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

E0776r

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96T

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ELISA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

E0776p

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

E0776d

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96T

ELISA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

E0776b

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96T

ELISA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

E0776m

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96T

ELISA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

E0776h

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96T

CLIA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

U0776d

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

U0776b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

U0776m

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

U0776h

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

U0776r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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CLIA Kit for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

U0776p

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

P0776Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

P0776Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Cat.:

P0776Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Protein for Mouse Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Isolation and characterisation of the mouse pyruvate dehydrogenase E1 alpha genes."
Fitzgerald G.F. , Hutchison W.M. , Dahl H.-H.M.
Biochim. Biophys. Acta1131:83-90(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Mammary gland.
3.

Lubec G. , Klug S. , Kang S.U.
Submitted (2007-04) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 46-58; 120-127; 133-141; 159-182; 216-244; 246-263; 268-274; 278-321; 324-343 AND 379-385;IDENTIFICATION BY MASS SPECTROMETRY
strain: C57BL/6.
tissue: Brain.
tissue: Hippocampus.
4.

"Inactivation of the murine pyruvate dehydrogenase (Pdha1) gene and its effect on early embryonic development."
Johnson M.T. , Mahmood S. , Hyatt S.L. , Yang H.S. , Soloway P.D. , Hanson R.W. , Patel M.S.
Mol. Genet. Metab.74:293-302(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;CATALYTIC ACTIVITY;FUNCTION
5.

"Oxidative metabolism of pyruvate is required for meiotic maturation of murine oocytes in vivo."
Johnson M.T. , Freeman E.A. , Gardner D.K. , Hunt P.A.
Biol. Reprod.77:2-8(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
6.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-232; SER-293; SER-295 AND SER-300;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
7.

"Tissue-specific pyruvate dehydrogenase complex deficiency causes cardiac hypertrophy and sudden death of weaned male mice."
Sidhu S. , Gangasani A. , Korotchkina L.G. , Suzuki G. , Fallavollita J.A. , Canty J.M. Jr. , Patel M.S.
Am. J. Physiol.295:H946-H952(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
8.

"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-301;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
9.

"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H. , Ye M. , Dong J. , Han G. , Jiang X. , Wu R. , Zou H.
J. Proteome Res.7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
10.

"Monitoring phosphorylation of the pyruvate dehydrogenase complex."
Rardin M.J. , Wiley S.E. , Naviaux R.K. , Murphy A.N. , Dixon J.E.
Anal. Biochem.389:157-164(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PHOSPHORYLATION AT SER-232; SER-293 AND SER-300
11.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-293;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"Beta-cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion."
Srinivasan M. , Choi C.S. , Ghoshal P. , Pliss L. , Pandya J.D. , Hill D. , Cline G. , Patel M.S.
Am. J. Physiol.299:E910-E917(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;CATALYTIC ACTIVITY;FUNCTION
13.

"Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation."
Jing E. , O'Neill B.T. , Rardin M.J. , Kleinridders A. , Ilkeyeva O.R. , Ussar S. , Bain J.R. , Lee K.Y. , Verdin E.M. , Newgard C.B. , Gibson B.W. , Kahn C.R.
Diabetes62:3404-3417(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-336;MUTAGENESIS OF LYS-336
14.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-313;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-63; LYS-244; LYS-277; LYS-313 AND LYS-385;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
tissue: Liver.
15.

"Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-63; LYS-244; LYS-267 AND LYS-321;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.

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