OPRL1 ELISA Kit for Human(Homo sapiens) | EIAab.comOPRL1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > OPRL1(Gene name) > Human

OPRL1 (Gene name),

Nociceptin receptor (Protein name ), OPRX_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

OPRL1(OOR;ORL1);

Protein name:

Nociceptin receptor;

Alternative:

Orphanin FQ receptor;Kappa-type 3 opioid receptor(KOR-3);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Receptor for the neuropeptide nociceptin/orphanin FQ. Has a potential role in modulating a number of brain functions, including instinctive behaviors and emotions. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

370

Sequence:

50:

100:

150:

200:

250:

300:

350:

370:

SIAKDVALAC | KTSETVPRPA |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P41146

MIM:

602548

Pfam:

PF00001

STRING:

9606.ENSP00000336764

UniGene:

Hs.2859

KEGG:

hsa:4987

String:

P41146

Uniprot:

P41146

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ELISA Kit for Human Nociceptin receptor

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E9791m

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96T

ELISA Kit for Human Nociceptin receptor

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E9791r

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96T

ELISA Kit for Human Nociceptin receptor

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E9791h

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Manual:

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ELISA Kit for Human Nociceptin receptor

Cat.:

E9791p

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96T

CLIA Kit for Human Nociceptin receptor

Cat.:

U9791r

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96T

CLIA Kit for Human Nociceptin receptor

Cat.:

U9791h

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96T

CLIA Kit for Human Nociceptin receptor

Cat.:

U9791p

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96T

CLIA Kit for Human Nociceptin receptor

Cat.:

U9791m

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96T

Polyclonal Antibody for Human Nociceptin receptor

Cat.:

P9791Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Nociceptin receptor

Cat.:

P9791Rb-h

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40ug/0.2ml

Monoclonal Antibody for Human Nociceptin receptor

Protein for Human Nociceptin receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization."
Mollereau C. , Parmentier M. , Mailleux P. , Butour J.-L. , Moisand C. , Chalon P. , Caput D. , Vassart G. , Meunier C.
FEBS Lett.341:33-38(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION
tissue: Brain stem.
2.

Lee P.H. , Zhu J. , Liu-Chen L. , Chang K.
Submitted (1996-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Nociceptin stimulates neutrophil chemotaxis and recruitment: Inhibition by aspirin-triggered-15-Epi-lipoxin A4."
Serhan C.N. , Fierro I.M. , Chiang N. , Pouliot M.
J. Immunol.166:3650-3654(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION
4.

"Identification and characterization of a splice variant of human kappa3-related opioid receptor (KOR-3D) gene."
Pan Y.-X. , Xu J. , Pasternak G.W.
Submitted (1999-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
5.

"cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
Warren C.N. , Aronstam R.S. , Sharma S.V.
Submitted (2003-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
6.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.

"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
9.

"Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines."
Wick M.J. , Minnerath S.R. , Roy S. , Ramakrishnan S. , Loh H.H.
Brain Res. Mol. Brain Res.32:342-347(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-333 (ISOFORM 1);TISSUE SPECIFICITY;INDUCTION
tissue: Lymphocyte.
10.

"Agonist-induced internalization and desensitization of the human nociceptin receptor expressed in CHO cells."
Spampinato S. , Di Toro R. , Alessandri M. , Murari G.
Cell. Mol. Life Sci.59:2172-2183(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
11.

"Serine 363 is required for nociceptin/orphanin FQ opioid receptor (NOPR) desensitization, internalization, and arrestin signaling."
Zhang N.R. , Planer W. , Siuda E.R. , Zhao H.C. , Stickler L. , Chang S.D. , Baird M.A. , Cao Y.Q. , Bruchas M.R.
J. Biol. Chem.287:42019-42030(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF SER-337; SER-346; SER-351 AND SER-363;PHOSPHORYLATION AT SER-363;SUBCELLULAR LOCATION
12.

"Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic."
Thompson A.A. , Liu W. , Chun E. , Katritch V. , Wu H. , Vardy E. , Huang X.P. , Trapella C. , Guerrini R. , Calo G. , Roth B.L. , Cherezov V. , Stevens R.C.
Nature485:395-399(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.01 ANGSTROMS) OF 43-339;FUNCTION;SUBCELLULAR LOCATION;TOPOLOGY;MUTAGENESIS OF GLN-107; ASP-110; ASP-130; TYR-131; GLN-280 AND TYR-309;DISULFIDE BOND

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