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Index > Protein center > OSMR(Gene name) > Human
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  • OSMR (Gene name),
  • Oncostatin-M-specific receptor subunit beta (Protein name ),  OSMR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    OSMR(OSMRB);
    Protein name:
    Oncostatin-M-specific receptor subunit beta;
    Alternative:
    Interleukin-31 receptor subunit beta(IL-31 receptor subunit beta;IL-31R subunit beta;IL-31R-beta;IL-31RB);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer composed of OSMR and IL6ST (type II OSM receptor). Heterodimer with IL31RA to form the IL31 receptor.
    Function:
    Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    979
    Sequence:
    50:
    MALFAVFQTT | FFLTLLSLRT | YQSEVLAERL | PLTPVSLKVS | TNSTRQSLHL | 
    100:
    QWTVHNLPYH | QELKMVFQIQ | ISRIETSNVI | WVGNYSTTVK | WNQVLHWSWE | 
    150:
    SELPLECATH | FVRIKSLVDD | AKFPEPNFWS | NWSSWEEVSV | QDSTGQDILF | 
    200:
    VFPKDKLVEE | GTNVTICYVS | RNIQNNVSCY | LEGKQIHGEQ | LDPHVTAFNL | 
    250:
    NSVPFIRNKG | TNIYCEASQG | NVSEGMKGIV | LFVSKVLEEP | KDFSCETEDF | 
    300:
    KTLHCTWDPG | TDTALGWSKQ | PSQSYTLFES | FSGEKKLCTH | KNWCNWQITQ | 
    350:
    DSQETYNFTL | IAENYLRKRS | VNILFNLTHR | VYLMNPFSVN | FENVNATNAI | 
    400:
    MTWKVHSIRN | NFTYLCQIEL | HGEGKMMQYN | VSIKVNGEYF | LSELEPATEY | 
    450:
    MARVRCADAS | HFWKWSEWSG | QNFTTLEAAP | SEAPDVWRIV | SLEPGNHTVT | 
    500:
    LFWKPLSKLH | ANGKILFYNV | VVENLDKPSS | SELHSIPAPA | NSTKLILDRC | 
    550:
    SYQICVIANN | SVGASPASVI | VISADPENKE | VEEERIAGTE | GGFSLSWKPQ | 
    600:
    PGDVIGYVVD | WCDHTQDVLG | DFQWKNVGPN | TTSTVISTDA | FRPGVRYDFR | 
    650:
    IYGLSTKRIA | CLLEKKTGYS | QELAPSDNPH | VLVDTLTSHS | FTLSWKDYST | 
    700:
    ESQPGFIQGY | HVYLKSKARQ | CHPRFEKAVL | SDGSECCKYK | IDNPEEKALI | 
    750:
    VDNLKPESFY | EFFITPFTSA | GEGPSATFTK | VTTPDEHSSM | LIHILLPMVF | 
    800:
    CVLLIMVMCY | LKSQWIKETC | YPDIPDPYKS | SILSLIKFKE | NPHLIIMNVS | 
    850:
    DCIPDAIEVV | SKPEGTKIQF | LGTRKSLTET | ELTKPNYLYL | LPTEKNHSGP | 
    900:
    GPCICFENLT | YNQAASDSGS | CGHVPVSPKA | PSMLGLMTSP | ENVLKALEKN | 
    950:
    YMNSLGEIPA | GETSLNYVSQ | LASPMFGDKD | SLPTNPVEAP | HCSEYKMQMA | 
    979:
    VSLRLALPPP | TENSSLSSIT | LLDPGEHYC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    String:
    MIM:
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    E1761h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    E1761r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    E1761m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    U1761m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    U1761r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    U1761h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    P1761Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    P1761Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Oncostatin-M-specific receptor subunit beta
    Cat.:
    P1761Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Oncostatin-M-specific receptor subunit beta
    Monoclonal Antibody for Human Oncostatin-M-specific receptor subunit beta
    Monoclonal Antibody for Human Oncostatin-M-specific receptor subunit beta
    Protein for Human Oncostatin-M-specific receptor subunit beta
    Protein for Human Oncostatin-M-specific receptor subunit beta
    Protein for Human Oncostatin-M-specific receptor subunit beta

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation."
      Mosley B. , De Imus C. , Friend D. , Boiani N. , Thoma B. , Park L.S. , Cosman D.
      J. Biol. Chem.271:32635-32643(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBUNIT;INDUCTION;TISSUE SPECIFICITY
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT TRP-210
      tissue: Colon.
      tissue: Placenta.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;OLIGOMERIZATION;INDUCTION
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-826 AND SER-889;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    5. 5.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PLCA1 ALA-618 AND THR-691
    7. 7.
      "Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis."
      Lin M.W. , Lee D.D. , Liu T.T. , Lin Y.F. , Chen S.Y. , Huang C.C. , Weng H.Y. , Liu Y.F. , Tanaka A. , Arita K. , Lai-Cheong J. , Palisson F. , Chang Y.T. , Wong C.K. , Matsuura I. , McGrath J.A. , Tsai S.F.
      Eur. J. Hum. Genet.18:26-32(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PLCA1 VAL-647; LEU-694 AND THR-697
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