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Index > Protein center > OTX2(Gene name) > Human
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  • OTX2 (Gene name),
  • Homeobox protein OTX2 (Protein name ),  OTX2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    OTX2;
    Protein name:
    Homeobox protein OTX2;
    Alternative:
    Orthodenticle homolog 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    289
    Sequence:
    50:
    MMSYLKQPPY | AVNGLSLTTS | GMDLLHPSVG | YPATPRKQRR | ERTTFTRAQL | 
    100:
    DVLEALFAKT | RYPDIFMREE | VALKINLPES | RVQVWFKNRR | AKCRQQQQQQ | 
    150:
    QNGGQNKVRP | AKKKTSPARE | VSSESGTSGQ | FTPPSSTSVP | TIASSSAPVS | 
    200:
    IWSPASISPL | SDPLSTSSSC | MQRSYPMTYT | QASGYSQGYA | GSTSYFGGMD | 
    250:
    CGSYLTPMHH | QLPGPGATLS | PMGTNAVTSH | LNQSPASLST | QGYGASSLGF | 
    289:
    NSTTDCLDYK | DQTASWKLNF | NADCLDYKDQ | TSSWKFQVL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    MIM:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Homeobox protein OTX2
    Cat.:
    E14438h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Homeobox protein OTX2
    Cat.:
    E14438r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Homeobox protein OTX2
    Cat.:
    E14438m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Homeobox protein OTX2
    Cat.:
    U14438h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Homeobox protein OTX2
    MSDS:
    Please sign in first.
    CLIA Kit for Human Homeobox protein OTX2
    Cat.:
    U14438m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Homeobox protein OTX2
    Polyclonal Antibody for Human Homeobox protein OTX2
    Polyclonal Antibody for Human Homeobox protein OTX2
    Monoclonal Antibody for Human Homeobox protein OTX2
    Monoclonal Antibody for Human Homeobox protein OTX2
    Monoclonal Antibody for Human Homeobox protein OTX2
    Protein for Human Homeobox protein OTX2
    Protein for Human Homeobox protein OTX2
    Protein for Human Homeobox protein OTX2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo."
      Simeone A. , Acampora D. , Mallamaci A. , Stornaiuolo A. , D'Apice M.R. , Nigro V. , Boncinelli E.
      EMBO J.12:2735-2747(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      Perrault I. , Rozet J.-M. , Gerber S. , Munnich A. , Kaplan J.
      Submitted (2000-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Elements regulating the transcription of human interstitial retinoid-binding protein (IRBP) gene in cultured retinoblastoma cells."
      Fong S.L. , Fong W.B.
      Curr. Eye Res.18:283-291(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Retina.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Cerebellum.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Eye.
    7. 7.
      Kitano T. , Kobayakawa H. , Saitou N.
      Submitted (2000-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 171-283
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MCOPS5 GLY-89; THR-133 AND ALA-134
    9. 10.
      "Expression of the homeobox genes PAX6, OTX2, and OTX1 in the early human fetal retina."
      Larsen K.B. , Lutterodt M. , Rath M.F. , Moeller M.
      Int. J. Dev. Neurosci.27:485-492(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    10. 11.
      "A novel dominant negative mutation of OTX2 associated with combined pituitary hormone deficiency."
      Diaczok D. , Romero C. , Zunich J. , Marshall I. , Radovick S.
      J. Clin. Endocrinol. Metab.93:4351-4359(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CPHD6 SER-225;CHARACTERIZATION OF VARIANT CPHD6 SER-225
    11. 12.
      "A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency."
      Ashkenazi-Hoffnung L. , Lebenthal Y. , Wyatt A.W. , Ragge N.K. , Dateki S. , Fukami M. , Ogata T. , Phillip M. , Gat-Yablonski G.
      Hum. Genet.127:721-729(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MCOPS5 SER-90;CHARACTERIZATION OF VARIANT MCOPS5 SER-90
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