Gene name:
SERPINE1 (PAI1;PLANH1) ;
Protein name:
Plasminogen activator inhibitor 1 (PAI;PAI-1) ;
Alternative:
Serpin E1 ;Endothelial plasminogen activator inhibitor ;
Organism:
SERPINE1 (Homo sapiens).
General Annotation
Sub Unit:
Interacts with VTN. Binds LRP1B; binding is followed by internalization and degradation.
Function:
This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.
Subcellular Location:
Secreted
Protein Attributes:
50:
MQMSPALTCL | VLGLALVFGE | GSAVHHPPSY | VAHLASDFGV | RVFQQVAQAS |
100:
KDRNVVFSPY | GVASVLAMLQ | LTTGGETQQQ | IQAAMGFKID | DKGMAPALRH |
150:
LYKELMGPWN | KDEISTTDAI | FVQRDLKLVQ | GFMPHFFRLF | RSTVKQVDFS |
200:
EVERARFIIN | DWVKTHTKGM | ISNLLGKGAV | DQLTRLVLVN | ALYFNGQWKT |
250:
PFPDSSTHRR | LFHKSDGSTV | SVPMMAQTNK | FNYTEFTTPD | GHYYDILELP |
300:
YHGDTLSMFI | AAPYEKEVPL | SALTNILSAQ | LISHWKGNMT | RLPRLLVLPK |
350:
FSLETEVDLR | KPLENLGMTD | MFRQFQADFT | SLSDQEPLHV | AQALQKVKIE |
400:
VNESGTVASS | STAVIVSARM | APEEIIMDRP | FLFVVRHNPT | GTVLFMGQVM |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Pig
Bovine
Polyclonal Antibody for Human PAI
Polyclonal Antibody for Human PAI
Polyclonal Antibody for Human PAI
Polyclonal Antibody for Human PAI
Polyclonal Antibody for Human PAI
Monoclonal Antibody for Human PAI
Monoclonal Antibody for Human PAI
Monoclonal Antibody for Human PAI
Monoclonal Antibody for Human PAI
Monoclonal Antibody for Human PAI
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
Zeng L. · Liu J. · Wang Y. · Wang L. · Weng S. · Chen S. · Yang G.-Y.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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Lung .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN PAI-1D
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.99 ANGSTROMS)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS)
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Cited for : VARIANT THR-15
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26.
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Daley G.Q.
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Lander E.S.
Nat. Genet.23:373-373(1999)
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Cited for : ERRATUM