PANX1 ELISA Kit for Human(Homo sapiens) | EIAab.comPANX1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PANX1(Gene name) > Human

PANX1 (Gene name),

Pannexin-1 (Protein name ), PANX1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PANX1(UNQ2529/PRO6028;MRS1);

Protein name:

Pannexin-1;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homohexamer. Forms homomeric or PANX1/PANX2-heteromeric intercellular channels on coexpression in paired Xenopus oocytes.

Function:

Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.

Subcellular Location:

Cell membrane Multi-pass membrane protein Cell junction gap junction Endoplasmic reticulum membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

426

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

426:

GMNIDSETKA | NNGEKNARQR | LLDSSC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.591976

String:

Q96RD7

STRING:

9606.ENSP00000227638

Pfam:

PF00876

KEGG:

hsa:24145

MIM:

608420

Uniprot:

Q96RD7

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ELISA Kit for Human Pannexin-1

Cat.:

E11281m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human Pannexin-1

Cat.:

E11281r

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MSDS:

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Packing:

96T

ELISA Kit for Human Pannexin-1

Cat.:

E11281h

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Manual:

Looking for manual.

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Packing:

96T

Range:

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CLIA Kit for Human Pannexin-1

Cat.:

U11281h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Pannexin-1

Cat.:

U11281r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Pannexin-1

Cat.:

U11281m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Pannexin-1

Cat.:

P11281Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Pannexin-1

Monoclonal Antibody for Human Pannexin-1

Protein for Human Pannexin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A novel cDNA of unknown function."
Bolger G.B. , Steele M.R.
Submitted (1998-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);VARIANT HIS-5
2.

"The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins."
Baranova A. , Ivanov D. , Petrash N. , Pestova A. , Skoblov M. , Kelmanson I. , Shagin D. , Nazarenko S. , Geraymovych E. , Litvin O. , Tiunova A. , Born T.L. , Usman N. , Staroverov D. , Lukyanov S. , Panchin Y.
Genomics83:706-716(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 2);VARIANT HIS-5
3.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT HIS-5
4.

"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
Otsuki T. , Ota T. , Nishikawa T. , Hayashi K. , Suzuki Y. , Yamamoto J. , Wakamatsu A. , Kimura K. , Sakamoto K. , Hatano N. , Kawai Y. , Ishii S. , Saito K. , Kojima S. , Sugiyama T. , Ono T. , Okano K. , Yoshikawa Y. , more...
DNA Res.12:117-126(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT HIS-5
5.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Bone.
7.

"Genomic organization of putative human gap junction proteins PANX1 and PANX2."
Baranova A.V. , Ivanov D.V. , Borodina T.A. , Panchin Y.V. , Shagin D.A. , Lukyanov S.A.
Submitted (2000-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 62-426
8.

"Functional implications of calcium permeability of the channel formed by pannexin 1."
Vanden Abeele F. , Bidaux G. , Gordienko D. , Beck B. , Panchin Y.V. , Baranova A.V. , Ivanov D.V. , Skryma R. , Prevarskaya N.
J. Cell Biol.174:535-546(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
9.

"Pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membrane."
Boassa D. , Ambrosi C. , Qiu F. , Dahl G. , Gaietta G. , Sosinsky G.
J. Biol. Chem.282:31733-31743(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-255;HOMOHEXAMERIZATION;SUBCELLULAR LOCATION;MUTAGENESIS OF ASN-255
10.

"Intracellular cysteine 346 is essentially involved in regulating Panx1 channel activity."
Bunse S. , Schmidt M. , Prochnow N. , Zoidl G. , Dermietzel R.
J. Biol. Chem.285:38444-38452(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF CYS-347

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