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Index > Protein center > F2RL3(Gene name) > Human
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  • F2RL3 (Gene name),
  • Proteinase-activated receptor 4 (Protein name ),  PAR4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    F2RL3(PAR4);
    Protein name:
    Proteinase-activated receptor 4(PAR-4);
    Alternative:
    Thrombin receptor-like 3;Coagulation factor II receptor-like 3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    385
    Sequence:
    50:
    MWGRLLLWPL | VLGFSLSGGT | QTPSVYDESG | STGGGDDSTP | SILPAPRGYP | 
    100:
    GQVCANDSDT | LELPDSSRAL | LLGWVPTRLV | PALYGLVLVV | GLPANGLALW | 
    150:
    VLATQAPRLP | STMLLMNLAA | ADLLLALALP | PRIAYHLRGQ | RWPFGEAACR | 
    200:
    LATAALYGHM | YGSVLLLAAV | SLDRYLALVH | PLRARALRGR | RLALGLCMAA | 
    250:
    WLMAAALALP | LTLQRQTFRL | ARSDRVLCHD | ALPLDAQASH | WQPAFTCLAL | 
    300:
    LGCFLPLLAM | LLCYGATLHT | LAASGRRYGH | ALRLTAVVLA | SAVAFFVPSN | 
    350:
    LLLLLHYSDP | SPSAWGNLYG | AYVPSLALST | LNSCVDPFIY | YYVSAEFRDK | 
    385:
    VRAGLFQRSP | GDTVASKASA | EGGSRGMGTH | SSLLQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    KEGG:
    UniGene:
    Pfam:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human PAR-4
    Cat.:
    E6592h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human PAR-4
    Cat.:
    E6592r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human PAR-4
    Cat.:
    E6592m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PAR-4
    Cat.:
    U6592m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PAR-4
    Cat.:
    U6592r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human PAR-4
    Cat.:
    U6592h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human PAR-4
    Polyclonal Antibody for Human PAR-4
    Cat.:
    P6592Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PAR-4
    Cat.:
    P6592Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human PAR-4
    Monoclonal Antibody for Human PAR-4
    Monoclonal Antibody for Human PAR-4
    Protein for Human PAR-4
    Protein for Human PAR-4
    Protein for Human PAR-4

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Gene and locus structure and chromosomal localization of the protease-activated receptor gene family."
      Kahn M.L. , Hammes S.R. , Botka C. , Coughlin S.R.
      J. Biol. Chem.273:23290-23296(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT THR-120
    2. 2.
      "A dual thrombin receptor system for platelet activation."
      Kahn M.L. , Zheng Y.-W. , Huang W. , Bigornia V. , Zeng D. , Moff S. , Farese R.V. Jr. , Tam C. , Coughlin S.R.
      Nature394:690-694(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT THR-120
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];MUTAGENESIS OF ARG-47 AND ARG-68;VARIANT THR-120
      tissue: Lymphoma.
    4. 4.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      King M.M. , Aronstam R.S. , Sharma S.V.
      Submitted (2003-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    5. 5.
      SeattleSNPs variation discovery resource
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS VAL-296 AND LEU-310
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    7. 7.
      "Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin."
      Kahn M.L. , Nakanishi-Matsui M. , Shapiro M.J. , Ishihara H. , Coughlin S.R.
      J. Clin. Invest.103:879-887(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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