PCGF6 ELISA Kit for Human(Homo sapiens) | EIAab.comPCGF6 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PCGF6(Gene name) > Human

PCGF6 (Gene name),

Polycomb group RING finger protein 6 (Protein name ), PCGF6_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

PCGF6(MBLR;RNF134);

Protein name:

Polycomb group RING finger protein 6;

Alternative:

RING finger protein 134;Mel18 and Bmi1-like RING finger;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Component of a PRC1-like complex. Interacts with BMI1/PCGF4, RING1 and RNF2. Interacts with KDM5D. Interacts with CBX4, CBX6, CBX7 and CBX8.

Function:

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

350

Sequence:

50:

100:

150:

200:

250:

300:

350:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:84108

UniGene:

Hs.335808

SMR:

Q9BYE7

MIM:

607816

String:

Q9BYE7

STRING:

9606.ENSP00000358862

Pfam:

PF00097

Uniprot:

Q9BYE7

FOR

ELISA Kit for Human Polycomb group RING finger protein 6

Cat.:

E12055m

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Packing:

96T

ELISA Kit for Human Polycomb group RING finger protein 6

Cat.:

E12055r

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Packing:

96T

ELISA Kit for Human Polycomb group RING finger protein 6

Cat.:

E12055h

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Manual:

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96T

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CLIA Kit for Human Polycomb group RING finger protein 6

Cat.:

U12055m

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Packing:

96T

CLIA Kit for Human Polycomb group RING finger protein 6

Cat.:

U12055r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Polycomb group RING finger protein 6

Cat.:

U12055h

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Packing:

96T

Polyclonal Antibody for Human Polycomb group RING finger protein 6

Cat.:

P12055Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Polycomb group RING finger protein 6

Monoclonal Antibody for Human Polycomb group RING finger protein 6

Protein for Human Polycomb group RING finger protein 6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation."
Akasaka T. , Takahashi N. , Suzuki M. , Koseki H. , Bodmer R. , Koga H.
Genes Cells7:835-850(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION IN TRANSCRIPTIONAL REPRESSION;INTERACTION WITH BMI1; RING1 AND RNF2;PHOSPHORYLATION AT SER-30;MUTAGENESIS OF SER-30; SER-57; SER-59 AND SER-69;VARIANT PRO-PRO-23 INS;SUBCELLULAR LOCATION
tissue: Testis.
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
3.

"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);VARIANT PRO-PRO-23 INS
tissue: Cervix.
tissue: Eye.
5.

"Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein."
Lee M.G. , Norman J. , Shilatifard A. , Shiekhattar R.
Cell128:877-887(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH KDM5D;IDENTIFICATION BY MASS SPECTROMETRY
6.

"Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus."
Maertens G.N. , El Messaoudi-Aubert S. , Racek T. , Stock J.K. , Nicholls J. , Rodriguez-Niedenfuhr M. , Gil J. , Peters G.
PLoS ONE4:E6380-E6380(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A PRC1-LIKE COMPLEX
7.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-115;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
8.

"Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells."
Vandamme J. , Volkel P. , Rosnoblet C. , Le Faou P. , Angrand P.O.
Mol. Cell. Proteomics0:0-0(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A PRC1-LIKE COMPLEX;INTERACTION WITH CBX4; CBX6; CBX7 AND CBX8;SUBCELLULAR LOCATION
9.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-115;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Solution structure of the RING domain of the human polycomb group RING finger protein 6."
RIKEN structural genomics initiative (RSGI)
Submitted (2007-03) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 124-182

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