PCK1 ELISA Kit for Human(Homo sapiens) | EIAab.comPCK1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PCK1(Gene name) > Human

PCK1 (Gene name),

Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Protein name ), PCKGC_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PCK1(PEPCK1);

Protein name:

Phosphoenolpyruvate carboxykinase, cytosolic [GTP](PEPCK-C);

Alternative:

Phosphoenolpyruvate carboxylase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer.

Function:

Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

622

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

622:

NADLPCEIER | EILALKQRIS | QM

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.1872

SMR:

P35558

STRING:

9606.ENSP00000319814

Pfam:

PF00821

MIM:

261680

KEGG:

hsa:5105

String:

P35558

Uniprot:

P35558

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ELISA Kit for Human PEPCK-C

Cat.:

E0936m

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Packing:

96T

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ELISA Kit for Human PEPCK-C

Cat.:

E0936r

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96T

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ELISA Kit for Human PEPCK-C

Cat.:

E0936h

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96T

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ELISA Kit for Human PEPCK-C

Cat.:

E0936c

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Packing:

96T

CLIA Kit for Human PEPCK-C

Cat.:

U0936r

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MSDS:

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Packing:

96T

CLIA Kit for Human PEPCK-C

Cat.:

U0936m

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MSDS:

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Packing:

96T

CLIA Kit for Human PEPCK-C

Cat.:

U0936h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human PEPCK-C

Cat.:

U0936c

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Packing:

96T

Polyclonal Antibody for Human PEPCK-C

Cat.:

P0936Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human PEPCK-C

Cat.:

P0936Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human PEPCK-C

Cat.:

P0936Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human PEPCK-C

Protein for Human PEPCK-C

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young."
Stoffel M. , Xiang K.S. , Espinosa R. III , Cox N.J. , le Beau M.M. , Bell G.I.
Hum. Mol. Genet.2:1-4(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS LEU-184 AND ASP-586
2.

"Phosphoenolpyruvate carboxykinase (GTP): characterization of the human PCK1 gene and localization distal to MODY on chromosome 20."
Ting C.-N. , Burgess D.L. , Chamberlain J.S. , Keith T.P. , Falls K. , Meisler M.H.
Genomics16:698-706(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT LEU-184
tissue: Liver.
3.

NIEHS SNPs program
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLN-55; THR-60; ILE-138; VAL-267; LYS-276; ILE-368 AND SER-427
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT LEU-184
tissue: Kidney.
tissue: Pericardium.
5.

"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT LEU-184
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS LEU-184 AND VAL-267
tissue: Kidney.
8.

"Structural and functional analysis of the human phosphoenolpyruvate carboxykinase gene promoter."
O'Brien R.M. , Printz R.L. , Halmi N. , Tiesinga J.J. , Granner D.K.
Biochim. Biophys. Acta1264:284-288(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-74
9.

"Regulation of phosphoenolpyruvate carboxykinase (GTP) gene transcription."
Liu J. , Hanson R.W.
Mol. Cell. Biochem.104:89-100(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
10.

"Regulation of cellular metabolism by protein lysine acetylation."
Zhao S. , Xu W. , Jiang W. , Yu W. , Lin Y. , Zhang T. , Yao J. , Zhou L. , Zeng Y. , Li H. , Li Y. , Shi J. , An W. , Hancock S.M. , He F. , Qin L. , Chin J. , Yang P. , more...
Science327:1000-1004(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-70; LYS-71 AND LYS-594;ENZYME REGULATION;MUTAGENESIS OF LYS-70; LYS-71 AND LYS-594;IDENTIFICATION BY MASS SPECTROMETRY
11.

"Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase."
Jiang W. , Wang S. , Xiao M. , Lin Y. , Zhou L. , Lei Q. , Xiong Y. , Guan K.L. , Zhao S.
Mol. Cell43:33-44(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-70; LYS-71 AND LYS-594;DEACETYLATION BY SIRT2;UBIQUITINATION BY UBR5
12.

"Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site."
Dunten P. , Belunis C. , Crowther R. , Hollfelder K. , Kammlott U. , Levin W. , Michel H. , Ramsey G.B. , Swain A. , Weber D. , Wertheimer S.J.
J. Mol. Biol.316:257-264(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) IN COMPLEX WITH GTP ANALOG; PEP AND MANGANESE;GTP-BINDING SITE;COFACTOR

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