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Index > Protein center > PCNA(Gene name) > Human
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  • PCNA (Gene name),
  • Proliferating cell nuclear antigen (Protein name ),  PCNA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    PCNA;
    Protein name:
    Proliferating cell nuclear antigen(PCNA);
    Alternative:
    Cyclin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer (By similarity). Forms a complex with activator 1 heteropentamer in the presence of ATP. Interacts with EXO1, POLH, POLK, DNMT1, ERCC5, FEN1, CDC6 and POLDIP2. Interacts with APEX2; this interaction is triggered by reactive oxygen species and increased by misincorporation of uracil in nuclear DNA. Forms a ternary complex with DNTTIP2 and core histone. Interacts with KCTD10 and PPP1R15A (By similarity). Interacts with POLD1, POLD3 and POLD4. Interacts with BAZ1B; the interaction is direct. Interacts with HLTF and SHPRH. Interacts with NUDT15. Interaction is disrupted in response to UV irradiation and acetylation. Interacts with CDKN1A/p21(CIP1) and CDT1; interacts via their PIP-box which also recruits the DCX(DTL) complex. Interacts with DDX11.
    Function:
    This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
    Subcellular Location:
    Nucleus Forms nuclear foci representing sites of ongoing DNA replication and vary in morphology and number during S phase. Together with APEX2, is redistributed in discrete nuclear foci in presence of oxidative DNA damaging agents.
    Protein Attributes:
    Sequence length:
    261
    Sequence:
    50:
    MFEARLVQGS | ILKKVLEALK | DLINEACWDI | SSSGVNLQSM | DSSHVSLVQL | 
    100:
    TLRSEGFDTY | RCDRNLAMGV | NLTSMSKILK | CAGNEDIITL | RAEDNADTLA | 
    150:
    LVFEAPNQEK | VSDYEMKLMD | LDVEQLGIPE | QEYSCVVKMP | SGEFARICRD | 
    200:
    LSHIGDAVVI | SCAKDGVKFS | ASGELGNGNI | KLSQTSNVDK | EEEAVTIEMN | 
    250:
    EPVQLTFALR | YLNFFTKATP | LSSTVTLSMS | ADVPLVVEYK | IADMGHLKYY | 
    261:
    LAPKIEDEEG | S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    KEGG:
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human PCNA
    Cat.:
    E0591m
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    ELISA Kit for Human PCNA
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    E0591h
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    96T
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    ELISA Kit for Human PCNA
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    E0591b
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    96T
    ELISA Kit for Human PCNA
    Cat.:
    E0591c
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    ELISA Kit for Human PCNA
    Cat.:
    E0591r
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    MSDS:
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    96T
    CLIA Kit for Human PCNA
    Cat.:
    U0591m
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    Packing:
    96T
    CLIA Kit for Human PCNA
    Cat.:
    U0591c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human PCNA
    Cat.:
    U0591b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human PCNA
    Cat.:
    U0591h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human PCNA
    Cat.:
    U0591r
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human PCNA
    Polyclonal Antibody for Human PCNA
    Cat.:
    P0591Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PCNA
    Cat.:
    P0591Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PCNA
    Polyclonal Antibody for Human PCNA
    Cat.:
    P0591Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human PCNA
    Monoclonal Antibody for Human PCNA
    Monoclonal Antibody for Human PCNA
    Monoclonal Antibody for Human PCNA
    Monoclonal Antibody for Human PCNA
    Protein for Human PCNA
    Protein for Human PCNA
    Protein for Human PCNA
    Protein for Human PCNA
    Protein for Human PCNA

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and sequence of the human nuclear protein cyclin: homology with DNA-binding proteins."
      Almendral J.M. , Huebsch D. , Blundell P.A. , Macdonald-Bravo H. , Bravo R.
      Proc. Natl. Acad. Sci. U.S.A.84:1575-1579(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structure of the human gene for the proliferating cell nuclear antigen."
      Travali S. , Ku D.H. , Rizzo M.G. , Ottavio L. , Baserga R. , Calabretta B.
      J. Biol. Chem.264:7466-7472(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      NIEHS SNPs program
      Submitted (2002-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skeletal muscle.
    5. 5.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Bone marrow.
      tissue: Lung.
    8. 8.
      "The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro."
      Prelich G. , Kostura M. , Marshak D.R. , Mathews M.B. , Stillman B.
      Nature326:471-475(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-26
    9. 9.
      Lubec G. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 169-181;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Fetal brain cortex.
    10. 10.
      "The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21."
      Gary R. , Ludwig D.L. , Cornelius H.L. , MacInnes M.A. , Park M.S.
      J. Biol. Chem.272:24522-24529(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ERCC5/XPG
    11. 11.
      "Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1."
      Chuang L.S.-H. , Ian H.-I. , Koh T.-W. , Ng H.-H. , Xu G. , Li B.F.L.
      Science277:1996-2000(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DNMT1
    12. 12.
      "Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase."
      Saha P. , Chen J. , Thome K.C. , Lawlis S.J. , Hou Z.H. , Hendricks M. , Parvin J.D. , Dutta A.
      Mol. Cell. Biol.18:2758-2767(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDC6
    13. 13.
      "Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen."
      Tsuchimoto D. , Sakai Y. , Sakumi K. , Nishioka K. , Sasaki M. , Fujiwara T. , Nakabeppu Y.
      Nucleic Acids Res.29:2349-2360(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH APEX2
    14. 14.
      "Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA."
      Haracska L. , Unk I. , Johnson R.E. , Phillips B.B. , Hurwitz J. , Prakash L. , Prakash S.
      Mol. Cell. Biol.22:784-791(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH POLK
    15. 15.
      "Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone."
      Fujita K. , Shimazaki N. , Ohta Y. , Kubota T. , Ibe S. , Toji S. , Tamai K. , Fujisaki S. , Hayano T. , Koiwai O.
      Genes Cells8:559-571(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DNTTIP2
    16. 16.
      "Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen."
      Liu L. , Rodriguez-Belmonte E.M. , Mazloum N. , Xie B. , Lee M.Y.W.T.
      J. Biol. Chem.278:10041-10047(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH POLDIP2
      tissue: Placenta.
    17. 17.
      "A defined human system that supports bidirectional mismatch-provoked excision."
      Dzantiev L. , Constantin N. , Genschel J. , Iyer R.R. , Burgers P.M. , Modrich P.
      Mol. Cell15:31-41(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EXO1
    18. 18.
      "Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage."
      Kannouche P.L. , Wing J. , Lehmann A.R.
      Mol. Cell14:491-500(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION;INTERACTION WITH POLH
    19. 19.
      "The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci."
      Poot R.A. , Bozhenok L. , van den Berg D.L.C. , Steffensen S. , Ferreira F. , Grimaldi M. , Gilbert N. , Ferreira J. , Varga-Weisz P.D.
      Nat. Cell Biol.6:1236-1244(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BAZ1B
    20. 20.
      "Functional roles of p12, the fourth subunit of human DNA polymerase delta."
      Li H. , Xie B. , Zhou Y. , Rahmeh A. , Trusa S. , Zhang S. , Gao Y. , Lee E.Y. , Lee M.Y.
      J. Biol. Chem.281:14748-14755(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH POLD1; POLD3 AND POLD4
    21. 21.
      "Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination."
      Motegi A. , Sood R. , Moinova H. , Markowitz S.D. , Liu P.P. , Myung K.
      J. Cell Biol.175:703-708(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SHPRH;UBIQUITINATION AT LYS-164;MUTAGENESIS OF LYS-164
    22. 22.
      "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1."
      Jin J. , Arias E.E. , Chen J. , Harper J.W. , Walter J.C.
      Mol. Cell23:709-721(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDT1
    23. 23.
      "Tyrosine phosphorylation controls PCNA function through protein stability."
      Wang S.C. , Nakajima Y. , Yu Y.L. , Xia W. , Chen C.T. , Yang C.C. , McIntush E.W. , Li L.Y. , Hawke D.H. , Kobayashi R. , Hung M.C.
      Nat. Cell Biol.8:1359-1368(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-211 BY EGFR;MUTAGENESIS OF TYR-211;INTERACTION WITH EGFR
    24. 24.
      "Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen."
      Unk I. , Hajdu I. , Fatyol K. , Szakal B. , Blastyak A. , Bermudez V. , Hurwitz J. , Prakash L. , Prakash S. , Haracska L.
      Proc. Natl. Acad. Sci. U.S.A.103:18107-18112(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION AT LYS-164;MUTAGENESIS OF LYS-164
    25. 25.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION
    26. 26.
      "PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex."
      Abbas T. , Sivaprasad U. , Terai K. , Amador V. , Pagano M. , Dutta A.
      Genes Dev.22:2496-2506(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDKN1A
    27. 27.
      "Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1."
      Farina A. , Shin J.H. , Kim D.H. , Bermudez V.P. , Kelman Z. , Seo Y.S. , Hurwitz J.
      J. Biol. Chem.283:20925-20936(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DDX11
    28. 28.
      "CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation."
      Nishitani H. , Shiomi Y. , Iida H. , Michishita M. , Takami T. , Tsurimoto T.
      J. Biol. Chem.283:29045-29052(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDKN1A
    29. 29.
      "Role of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease activities of human Ape2 in repair of oxidative DNA damage."
      Burkovics P. , Hajdu I. , Szukacsov V. , Unk I. , Haracska L.
      Nucleic Acids Res.37:4247-4255(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH APEX2
    30. 30.
      "Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination."
      Unk I. , Hajdu I. , Fatyol K. , Hurwitz J. , Yoon J.-H. , Prakash L. , Prakash S. , Haracska L.
      Proc. Natl. Acad. Sci. U.S.A.105:3768-3773(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION;INTERACTION WITH HLTF
    31. 31.
      "Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks."
      Motegi A. , Liaw H.-J. , Lee K.-Y. , Roest H.P. , Maas A. , Wu X. , Moinova H. , Markowitz S.D. , Ding H. , Hoeijmakers J.H.J. , Myung K.
      Proc. Natl. Acad. Sci. U.S.A.105:12411-12416(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION;FUNCTION;INTERACTION WITH HLTF AND SHPRH;MUTAGENESIS OF LYS-164
    32. 32.
      "Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2."
      Yu Y. , Cai J.-P. , Tu B. , Wu L. , Zhao Y. , Liu X. , Li L. , McNutt M.A. , Feng J. , He Q. , Yang Y. , Wang H. , Sekiguchi M. , Zhu W.-G.
      J. Biol. Chem.284:19310-19320(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NUDT15;ACETYLATION AT LYS-14
    33. 33.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-77; LYS-80 AND LYS-248;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    34. 34.
      "CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis."
      Terai K. , Abbas T. , Jazaeri A.A. , Dutta A.
      Mol. Cell37:143-149(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION;MUTAGENESIS OF LYS-164
    35. 35.
      "Metnase promotes restart and repair of stalled and collapsed replication forks."
      De Haro L.P. , Wray J. , Williamson E.A. , Durant S.T. , Corwin L. , Gentry A.C. , Osheroff N. , Lee S.H. , Hromas R. , Nickoloff J.A.
      Nucleic Acids Res.38:5681-5691(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SETMAR
    36. 36.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    37. 37.
      "Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1."
      Rowbotham S.P. , Barki L. , Neves-Costa A. , Santos F. , Dean W. , Hawkes N. , Choudhary P. , Will W.R. , Webster J. , Oxley D. , Green C.M. , Varga-Weisz P. , Mermoud J.E.
      Mol. Cell42:285-296(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SMARCAD1
    38. 38.
      "Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate."
      Emanuele M.J. , Ciccia A. , Elia A.E. , Elledge S.J.
      Proc. Natl. Acad. Sci. U.S.A.108:9845-9850(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KIAA0101
    39. 39.
      "Inhibition of homologous recombination by the PCNA-interacting protein PARI."
      Moldovan G.L. , Dejsuphong D. , Petalcorin M.I. , Hofmann K. , Takeda S. , Boulton S.J. , D'Andrea A.D.
      Mol. Cell45:75-86(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PARPBP;SUMOYLATION
    40. 40.
      "Spartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage response."
      Centore R.C. , Yazinski S.A. , Tse A. , Zou L.
      Mol. Cell46:625-635(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SPRTN
    41. 41.
      "ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response."
      Weston R. , Peeters H. , Ahel D.
      Genes Dev.26:1558-1572(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZRANB3
    42. 42.
      "The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA and participates in cellular response to replication stress."
      Yuan J. , Ghosal G. , Chen J.
      Mol. Cell47:410-421(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZRANB3
    43. 43.
      "Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass."
      Povlsen L.K. , Beli P. , Wagner S.A. , Poulsen S.L. , Sylvestersen K.B. , Poulsen J.W. , Nielsen M.L. , Bekker-Jensen S. , Mailand N. , Choudhary C.
      Nat. Cell Biol.14:1089-1098(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KIAA0101
    44. 44.
      "Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress."
      Ciccia A. , Nimonkar A.V. , Hu Y. , Hajdu I. , Achar Y.J. , Izhar L. , Petit S.A. , Adamson B. , Yoon J.C. , Kowalczykowski S.C. , Livingston D.M. , Haracska L. , Elledge S.J.
      Mol. Cell47:396-409(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZRANB3
    45. 45.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDKN1C
    46. 46.
      "RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication."
      Vannier J.B. , Sandhu S. , Petalcorin M.I. , Wu X. , Nabi Z. , Ding H. , Boulton S.J.
      Science342:239-242(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RTEL1;SUBCELLULAR LOCATION
    47. 47.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ATLD2;INTERACTION WITH FEN1; LIG1 AND ERCC5;VARIANT ATLD2 ILE-228;CHARACTERIZATION OF VARIANT ATDL2 ILE-228
    48. 48.
      "Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components."
      Alabert C. , Bukowski-Wills J.C. , Lee S.B. , Kustatscher G. , Nakamura K. , de Lima Alves F. , Menard P. , Mejlvang J. , Rappsilber J. , Groth A.
      Nat. Cell Biol.16:281-293(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FAM111A
    49. 49.
      "Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA."
      Gulbis J.M. , Kelman Z. , Hurwitz J. , O'Donnell M. , Kuriyan J.
      Cell87:297-306(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS)
    50. 50.
      "Structural basis for recruitment of human flap endonuclease 1 to PCNA."
      Sakurai S. , Kitano K. , Yamaguchi H. , Hamada K. , Okada K. , Fukuda K. , Uchida M. , Ohtsuka E. , Morioka H. , Hakoshima T.
      EMBO J.24:683-693(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) IN COMPLEX WITH FEN1
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