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Index > Protein center > PDCD1(Gene name) > Human
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  • PDCD1 (Gene name),
  • Programmed cell death protein 1 (Protein name ),  PDCD1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    PDCD1(PD1);
    Protein name:
    Programmed cell death protein 1(Protein PD-1;hPD-1);
    Alternative:

    CD:
    CD279;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Inhibitory cell surface receptor involved in the regulation of T cell function during immunity and tolerance. Upon ligand binding, inhibits T cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    288
    Sequence:
    50:
    MQIPQAPWPV | VWAVLQLGWR | PGWFLDSPDR | PWNPPTFSPA | LLVVTEGDNA | 
    100:
    TFTCSFSNTS | ESFVLNWYRM | SPSNQTDKLA | AFPEDRSQPG | QDCRFRVTQL | 
    150:
    PNGRDFHMSV | VRARRNDSGT | YLCGAISLAP | KAQIKESLRA | ELRVTERRAE | 
    200:
    VPTAHPSPSP | RPAGQFQTLV | VGVVGGLLGS | LVLLVWVLAV | ICSRAARGTI | 
    250:
    GARRTGQPLK | EDPSAVPVFS | VDYGELDFQW | REKTPEPPVP | CVPEQTEYAT | 
    288:
    IVFPSGMGTS | SPARRGSADG | PRSAQPLRPE | DGHCSWPL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    String:
    KEGG:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein PD-1
    Cat.:
    E0515h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Protein PD-1
    Cat.:
    E0515m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Protein PD-1
    Cat.:
    U0515h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Protein PD-1
    Cat.:
    U0515m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Protein PD-1
    Cat.:
    P0515Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Protein PD-1
    Cat.:
    P0515Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Protein PD-1
    Monoclonal Antibody for Human Protein PD-1
    Protein for Human Protein PD-1
    Protein for Human Protein PD-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Structure and chromosomal localization of the human PD-1 gene (PDCD1)."
      Shinohara T. , Taniwaki M. , Ishida Y. , Kawaich M. , Honjo T.
      Genomics23:704-706(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors."
      Finger L.R. , Pu J. , Wasserman R. , Vibhakar R. , Louie E. , Hardy R.R. , Burrows P.D. , Billips L.D.
      Gene197:177-187(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];INVOLVEMENT IN SLEB2
    5. 5.
      "Cloning of PD-1 cDNA from activated peripheral leukocytes."
      He X. , Xu L. , Liu Y. , Zeng Y.
      Submitted (2003-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The role of the PD-1 pathway in autoimmunity and peripheral tolerance."
      Fife B.T. , Pauken K.E.
      Ann. N. Y. Acad. Sci.1217:45-59(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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