Pdgfb ELISA Kit for Mouse(Mus musculus) | EIAab.comPdgfb ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Pdgfb(Gene name) > Mouse

Pdgfb (Gene name),

Platelet-derived growth factor subunit B (Protein name ), PDGFB_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Pdgfb(Sis);

Protein name:

Platelet-derived growth factor subunit B(PDGF subunit B);

Alternative:

Platelet-derived growth factor B chain;PDGF-2;Proto-oncogene c-Sis;Platelet-derived growth factor beta polypeptide;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with XLKD1.

Function:

Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

241

Sequence:

50:

100:

150:

200:

241:

AKTPQARVTI | RTVRIRRPPK | GKHRKFKHTH | DKAALKETLG | A

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:18591

SMR:

P31240

String:

P31240

Pfam:

PF00341

UniGene:

Mm.144089

Uniprot:

P31240

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ELISA Kit for Mouse PDGF subunit B

Cat.:

E0633m

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96T

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ELISA Kit for Mouse PDGF subunit B

MSDS:

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ELISA Kit for Mouse PDGF subunit B

Cat.:

E0633r

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96T

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ELISA Kit for Mouse PDGF subunit B

Cat.:

E0633h

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96T

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ELISA Kit for Mouse PDGF subunit B

Cat.:

E0633d

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96T

CLIA Kit for Mouse PDGF subunit B

Cat.:

U0633d

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MSDS:

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Packing:

96T

CLIA Kit for Mouse PDGF subunit B

Cat.:

U0633h

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Manual:

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Packing:

96T

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CLIA Kit for Mouse PDGF subunit B

Cat.:

U0633r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse PDGF subunit B

MSDS:

Please sign in first.

CLIA Kit for Mouse PDGF subunit B

Cat.:

U0633m

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Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Mouse PDGF subunit B

Cat.:

P0633Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse PDGF subunit B

Cat.:

P0633Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse PDGF subunit B

Cat.:

P0633Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse PDGF subunit B

Monoclonal Antibody for Mouse PDGF subunit B

Protein for Mouse PDGF subunit B

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding the B chain of platelet-derived growth factor."
Bonthron D.T. , Sultan P. , Collins T.
Genomics10:287-292(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Embryo.
tissue: Mammary gland.
3.

"Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities."
Leveen P. , Pekny M. , Gebre-Medhin S. , Swolin B. , Larsson E. , Betsholtz C.
Genes Dev.8:1875-1887(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
4.

"Pericyte loss and microaneurysm formation in PDGF-B-deficient mice."
Lindahl P. , Johansson B.R. , Leveen P. , Betsholtz C.
Science277:242-245(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
5.

"Platelet-derived growth factor receptor beta regulates migration and DNA synthesis in metanephric mesenchymal cells."
Arar M. , Xu Y.C. , Elshihabi I. , Barnes J.L. , Choudhury G.G. , Abboud H.E.
J. Biol. Chem.275:9527-9533(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF beta-receptor null mice."
Kaminski W.E. , Lindahl P. , Lin N.L. , Broudy V.C. , Crosby J.R. , Hellstrom M. , Swolin B. , Bowen-Pope D.F. , Martin P.J. , Ross R. , Betsholtz C. , Raines E.W.
Blood97:1990-1998(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
7.

"Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury."
Taneda S. , Hudkins K.L. , Topouzis S. , Gilbertson D.G. , Ophascharoensuk V. , Truong L. , Johnson R.J. , Alpers C.E.
J. Am. Soc. Nephrol.14:2544-2555(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
8.

"Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors."
Abramsson A. , Lindblom P. , Betsholtz C.
J. Clin. Invest.112:1142-1151(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"PDGF signaling in cells and mice."
Tallquist M. , Kazlauskas A.
Cytokine Growth Factor Rev.15:205-213(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
10.

"Insight into the physiological functions of PDGF through genetic studies in mice."
Betsholtz C.
Cytokine Growth Factor Rev.15:215-228(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION;DISRUPTION PHENOTYPE
11.

"Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells."
Wu E. , Palmer N. , Tian Z. , Moseman A.P. , Galdzicki M. , Wang X. , Berger B. , Zhang H. , Kohane I.S.
PLoS ONE3:E3794-E3794(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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