PDGFD ELISA Kit for Human(Homo sapiens) | EIAab.comPDGFD ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PDGFD(Gene name) > Human

PDGFD (Gene name),

Platelet-derived growth factor D (Protein name ), PDGFD_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PDGFD(MSTP036;UNQ1899/PRO4345;IEGF;SCDGFB);

Protein name:

Platelet-derived growth factor D(PDGF-D);

Alternative:

Spinal cord-derived growth factor B(SCDGF-B);Iris-expressed growth factor;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer; disulfide-linked.

Function:

Potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. Activated by proteolytic cleavage and this active form acts as a specific ligand for beta platelet-derived growth factor receptor. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

370

Sequence:

50:

100:

150:

200:

250:

300:

350:

370:

DIQLDHHERC | DCICSSRPPR |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9GZP0

String:

Q9GZP0

UniGene:

Hs.352298

Pfam:

PF00431

MIM:

609673

STRING:

9606.ENSP00000376865

KEGG:

hsa:80310

Uniprot:

Q9GZP0

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ELISA Kit for Human PDGF-D

Cat.:

E1896h

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96T

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ELISA Kit for Human PDGF-D

Cat.:

E1896r

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96T

ELISA Kit for Human PDGF-D

Cat.:

E1896m

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MSDS:

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Packing:

96T

ELISA Kit for Human PDGF-D

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CLIA Kit for Human PDGF-D

Cat.:

U1896m

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96T

CLIA Kit for Human PDGF-D

Cat.:

U1896r

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MSDS:

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Packing:

96T

CLIA Kit for Human PDGF-D

Cat.:

U1896h

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Manual:

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96T

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CLIA Kit for Human PDGF-D

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Polyclonal Antibody for Human PDGF-D

Cat.:

P1896Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human PDGF-D

Cat.:

P1896Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human PDGF-D

Cat.:

P1896Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human PDGF-D

Protein for Human PDGF-D

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular cloning of SCDGF-B, a novel growth factor homologous to SCDGF/PDGF-C/fallotein."
Hamada T. , Ui-Tei K. , Imaki J. , Miyata Y.
Biochem. Biophys. Res. Commun.280:733-737(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
2.

"PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor."
Bergsten E. , Uutela M. , Li X. , Pietras K. , Oestman A. , Heldin C.-H. , Alitalo K. , Eriksson U.
Nat. Cell Biol.3:512-516(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBUNIT;TISSUE SPECIFICITY
3.

"PDGF D, a novel protease-activated growth factor."
LaRochelle W.J. , Jeffers M. , McDonald W.F. , Chillakuru R.A. , Giese N.A. , Lokker N.A. , Sullivan C. , Boldog F.L. , Yang M. , Vernet C. , Burgess C.E. , Fernandez E. , Deegler L.L. , Rittman B. , Shimkets J. , Shimkets R.A. , Rothberg J.M. , Lichenstein H.S.
Nat. Cell Biol.3:517-521(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBUNIT;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
4.

"Expressed sequence tag analysis of adult human iris for the NEIBank project: steroid-response factors and similarities with retinal pigment epithelium."
Wistow G. , Bernstein S.L. , Ray S. , Wyatt M.K. , Behal A. , Touchman J.W. , Bouffard G. , Smith D. , Peterson K.
Mol. Vis.8:185-195(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Iris.
5.

Liu B. , Liu Y.Q. , Wang X.Y. , Zhao B. , Sheng H. , Zhao X.W. , Liu S. , Xu Y.Y. , Ye J. , Song L. , Gao Y. , Zhang C.L. , Zhang J. , Wei Y.J. , Cao H.Q. , Zhao Y. , Liu L.S. , Ding J.F. , more...
Submitted (1998-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Aorta.
6.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
7.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Trachea.
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Testis.
10.

"Platelet-derived growth factor-D expression in developing and mature human kidneys."
Changsirikulchai S. , Hudkins K.L. , Goodpaster T.A. , Volpone J. , Topouzis S. , Gilbertson D.G. , Alpers C.E.
Kidney Int.62:2043-2054(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 64-369;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
11.

"Chromosomal location, exon structure, and vascular expression patterns of the human PDGFC and PDGFC genes."
Uutela M. , Lauren J. , Bergsten E. , Li X. , Horelli-Kuitunen N. , Eriksson U. , Alitalo K.
Circulation103:2242-2247(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
12.

"Platelet-derived growth factor D: tumorigenicity in mice and dysregulated expression in human cancer."
LaRochelle W.J. , Jeffers M. , Corvalan J.R.F. , Jia X.-C. , Feng X. , Vanegas S. , Vickroy J.D. , Yang X.-D. , Chen F. , Gazit G. , Mayotte J. , Macaluso J. , Rittman B. , Wu F. , Dhanabal M. , Herrmann J. , Lichenstein H.S.
Cancer Res.62:2468-2473(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
13.

"Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury."
Taneda S. , Hudkins K.L. , Topouzis S. , Gilbertson D.G. , Ophascharoensuk V. , Truong L. , Johnson R.J. , Alpers C.E.
J. Am. Soc. Nephrol.14:2544-2555(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
14.

"PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis."
Uutela M. , Wirzenius M. , Paavonen K. , Rajantie I. , He Y. , Karpanen T. , Lohela M. , Wiig H. , Salven P. , Pajusola K. , Eriksson U. , Alitalo K.
Blood104:3198-3204(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
15.

"Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family."
Reigstad L.J. , Varhaug J.E. , Lillehaug J.R.
FEBS J.272:5723-5741(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
16.

"Platelet-derived growth factor D is activated by urokinase plasminogen activator in prostate carcinoma cells."
Ustach C.V. , Kim H.-R.C.
Mol. Cell. Biol.25:6279-6288(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;PTM;MUTAGENESIS OF ARG-247 AND ARG-249
17.

"Emerging roles of PDGF-D signaling pathway in tumor development and progression."
Wang Z. , Ahmad A. , Li Y. , Kong D. , Azmi A.S. , Banerjee S. , Sarkar F.H.
Biochim. Biophys. Acta1806:122-130(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
18.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] TYR-202

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