PEG10 ELISA Kit for Human(Homo sapiens) | EIAab.comPEG10 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > PEG10(Gene name) > Human

PEG10 (Gene name),

Retrotransposon-derived protein PEG10 (Protein name ), PEG10_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

PEG10(EDR;KIAA1051;MAR2;MART2;MEF3L1;RGAG3);

Protein name:

Retrotransposon-derived protein PEG10;

Alternative:

Mammalian retrotransposon-derived protein 2;Embryonal carcinoma differentiation-regulated protein;Paternally expressed gene 10 protein;Myelin expression factor 3-like protein 1(MEF3-like protein 1);Retrotransposon-derived gag-like polyprotein;Retrotransposon gag domain-containing protein 3;Ty3/Gypsy-like protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with ALK1, SIAH1 and SIAH2.

Function:

Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter.

Subcellular Location:

Nucleus Cytoplasm Detected predominantly in the cytoplasm of breast and prostate carcinomas, in hepatocellular carcinoma (HCC) and B-cell chronic lymphocytic leukemia (B-CLL) cells and in the HepG2 cell line. Colocalized with ALK1.

Protein Attributes:

Sequence length:

708

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

708:

PPPSYSTL

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

STRING:

9606.ENSP00000417587

Pfam:

PF03732

String:

Q86TG7

UniGene:

Hs.147492

KEGG:

hsa:23089

MIM:

609810

Uniprot:

Q86TG7

FOR

ELISA Kit for Human Retrotransposon-derived protein PEG10

Cat.:

E3142h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human Retrotransposon-derived protein PEG10

Cat.:

E3142m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Retrotransposon-derived protein PEG10

Cat.:

U3142h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Retrotransposon-derived protein PEG10

Cat.:

U3142m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Retrotransposon-derived protein PEG10

Cat.:

P3142Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Retrotransposon-derived protein PEG10

Cat.:

P3142Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Retrotransposon-derived protein PEG10

Protein for Human Retrotransposon-derived protein PEG10

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A retrotransposon-derived gene, PEG10, is a novel imprinted gene located on human chromosome 7q21."
Ono R. , Kobayashi S. , Wagatsuma H. , Aisaka K. , Kohda T. , Kaneko-Ishino T. , Ishino F.
Genomics73:232-237(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
2.

"Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
DNA Res.6:63-70(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
3.

Ohara O. , Nagase T. , Kikuno R.
Submitted (1999-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
4.

"Isolation of MEF3 like gene 1."
Satoh S. , Furukawa Y.
Submitted (2002-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Testis.
5.

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: PNS.
7.

"Temporal regulation of the expression of syncytin (HERV-W), maternally imprinted PEG10, and SGCE in human placenta."
Smallwood A. , Papageorghiou A. , Nicolaides K. , Alley M.K.R. , Jim A. , Nargund G. , Ojha K. , Campbell S. , Banerjee S.
Biol. Reprod.69:286-293(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
8.

"Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1."
Okabe H. , Satoh S. , Furukawa Y. , Kato T. , Hasegawa S. , Nakajima Y. , Yamaoka Y. , Nakamura Y.
Cancer Res.63:3043-3048(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SIAH1 AND SIAH2;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
9.

"Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1."
Lux A. , Beil C. , Majety M. , Barron S. , Gallione C.J. , Kuhn H.-M. , Berg J.N. , Kioschis P. , Marchuk D.A. , Hafner M.
J. Biol. Chem.280:8482-8493(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ALK1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
10.

"PEG10 is a c-MYC target gene in cancer cells."
Li C.-M. , Margolin A.A. , Salas M. , Memeo L. , Mansukhani M. , Hibshoosh H. , Szabolcs M. , Klinakis A. , Tycko B.
Cancer Res.66:665-672(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
11.

"Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia."
Kainz B. , Shehata M. , Bilban M. , Kienle D. , Heintel D. , Kroemer-Holzinger E. , Le T. , Kroeber A. , Heller G. , Schwarzinger I. , Demirtas D. , Chott A. , Doehner H. , Zoechbauer-Mueller S. , Fonatsch C. , Zielinski C. , Stilgenbauer S. , Gaiger A. , more...
Int. J. Cancer121:1984-1993(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
12.

"Mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues."
Clark M.B. , Jaenicke M. , Gottesbuehren U. , Kleffmann T. , Legge M. , Poole E.S. , Tate W.P.
J. Biol. Chem.282:37359-37369(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RIBOSOMAL FRAMESHIFT;PROTEOLYTIC PROCESSING;MUTAGENESIS OF ASP-370;DEVELOPMENTAL STAGE
13.

"Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells."
Jie X. , Lang C. , Jian Q. , Chaoqun L. , Dehua Y. , Yi S. , Yanping J. , Luokun X. , Qiuping Z. , Hui W. , Feili G. , Boquan J. , Youxin J. , Jinquan T.
Oncogene26:5741-5751(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
14.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-316 AND SER-321 (ISOFORM RF1);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
15.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-321 (ISOFORM RF1);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
16.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

Product Feedback Wall

* Email:
*Comments: