PEPD ELISA Kit for Human(Homo sapiens) | EIAab.comPEPD ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PEPD(Gene name) > Human

PEPD (Gene name),

Xaa-Pro dipeptidase (Protein name ), PEPD_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PEPD(PRD);

Protein name:

Xaa-Pro dipeptidase(X-Pro dipeptidase);

Alternative:

Peptidase D;Imidodipeptidase;Proline dipeptidase(Prolidase);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer.

Function:

Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because the high level of iminoacids in collagen.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

493

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

493:

IEEDVVVTDS | GIELLTCVPR | TVEEIEACMA | GCDKAFTPFS | GPK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:5184

SMR:

P12955

UniGene:

Hs.36473

String:

P12955

MIM:

170100

Pfam:

PF05195

STRING:

9606.ENSP00000244137

Uniprot:

P12955

FOR

ELISA Kit for Human X-Pro dipeptidase

Cat.:

E9177h

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Manual:

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Packing:

96T

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ELISA Kit for Human X-Pro dipeptidase

Cat.:

E9177r

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96T

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ELISA Kit for Human X-Pro dipeptidase

Cat.:

E9177m

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Packing:

96T

CLIA Kit for Human X-Pro dipeptidase

Cat.:

U9177r

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human X-Pro dipeptidase

Cat.:

U9177h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human X-Pro dipeptidase

Cat.:

U9177m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human X-Pro dipeptidase

Cat.:

P9177Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human X-Pro dipeptidase

Cat.:

P9177Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human X-Pro dipeptidase

Protein for Human X-Pro dipeptidase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Primary structure and gene localization of human prolidase."
Endo F. , Tanoue A. , Nakai H. , Hata A. , Indo Y. , Titani K. , Matsuda I.
J. Biol. Chem.264:4476-4481(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
tissue: Liver.
tissue: Placenta.
2.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3);VARIANT PHE-435
tissue: Brain.
tissue: Kidney.
4.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT PHE-435
tissue: Kidney.
tissue: Skin.
tissue: Uterus.
6.

"Cluster analysis of an extensive human breast cancer cell line protein expression map database."
Harris R.A. , Yang A. , Stein R.C. , Lucy K. , Brusten L. , Herath A. , Parekh R. , Waterfield M.D. , O'Hare M.J. , Neville M.A. , Page M.J. , Zvelebil M.J.
Proteomics2:212-223(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MASS SPECTROMETRY
tissue: Mammary cancer.
7.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
8.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Crystal structure of human prolidase: the molecular basis of PD disease."
Protein structure factory (PSF)
Submitted (2009-02) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.82 ANGSTROMS) IN COMPLEX WITH MANGANESE IONS;COFACTOR
11.

"A single nucleotide change in the prolidase gene in fibroblasts from two patients with polypeptide positive prolidase deficiency. Expression of the mutant enzyme in NIH 3T3 cells."
Tanoue A. , Endo F. , Kitano A. , Matsuda I.
J. Clin. Invest.86:351-355(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PD ASN-276
12.

"Four novel PEPD alleles causing prolidase deficiency."
Ledoux P. , Scriver C.R. , Hechtman P.
Am. J. Hum. Genet.54:1014-1021(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PD ARG-448 AND GLU-452 DEL
13.

"Expression and molecular analysis of mutations in prolidase deficiency."
Ledoux P. , Scriver C.R. , Hechtman P.
Am. J. Hum. Genet.59:1035-1039(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PD GLN-184; ASP-278; ARG-448 AND GLU-452 DEL
14.

"Mutation analysis of five new patients affected by prolidase deficiency: the lack of enzyme activity causes necrosis-like cell death in cultured fibroblasts."
Forlino A. , Lupi A. , Vaghi P. , Icaro Cornaglia A. , Calligaro A. , Campari E. , Cetta G.
Hum. Genet.111:314-322(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PD ARG-448

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