PHLDA2 ELISA Kit for Human(Homo sapiens) | EIAab.comPHLDA2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PHLDA2(Gene name) > Human

PHLDA2 (Gene name),

Pleckstrin homology-like domain family A member 2 (Protein name ), PHLA2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PHLDA2(BWR1C;HLDA2;IPL;TSSC3);

Protein name:

Pleckstrin homology-like domain family A member 2;

Alternative:

Imprinted in placenta and liver protein;Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein;Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein;Tumor-suppressing STF cDNA 3 protein;p17-Beckwith-Wiedemann region 1 C(p17-BWR1C);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.

Subcellular Location:

Cytoplasm Membrane Peripheral membrane protein

Protein Attributes:

Sequence length:

152

Sequence:

50:

100:

150:

152:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.154036

MIM:

602131

KEGG:

hsa:7262

String:

Q53GA4

STRING:

9606.ENSP00000319231

SMR:

Q53GA4

Uniprot:

Q53GA4

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ELISA Kit for Human Pleckstrin homology-like domain family A member 2

Cat.:

E0401h

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Manual:

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96T

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ELISA Kit for Human Pleckstrin homology-like domain family A member 2

Cat.:

E0401m

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Packing:

96T

ELISA Kit for Human Pleckstrin homology-like domain family A member 2

Cat.:

E0401b

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96T

CLIA Kit for Human Pleckstrin homology-like domain family A member 2

Cat.:

U0401b

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Packing:

96T

CLIA Kit for Human Pleckstrin homology-like domain family A member 2

Cat.:

U0401h

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Pleckstrin homology-like domain family A member 2

Cat.:

U0401m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Pleckstrin homology-like domain family A member 2

Cat.:

P0401Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Pleckstrin homology-like domain family A member 2

Cat.:

P0401Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Pleckstrin homology-like domain family A member 2

Monoclonal Antibody for Human Pleckstrin homology-like domain family A member 2

Protein for Human Pleckstrin homology-like domain family A member 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes."
Hu R.-J. , Lee M.P. , Connors T.D. , Johnson L.A. , Burn T.C. , Su K. , Landes G.M. , Feinberg A.P.
Genomics46:9-17(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis."
Qian N. , Frank D. , O'Keefe D. , Dao D. , Zhao L. , Yuan L. , Wang Q. , Keating M. , Walsh C. , Tycko B.
Hum. Mol. Genet.6:2021-2029(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
3.

"Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples."
Schwienbacher C. , Sabbioni S. , Campi M. , Veronese A. , Bernardi G. , Menegatti A. , Hatada I. , Mukai T. , Ohashi H. , Barbanti-Brodano G. , Croce C.M. , Negrini M.
Proc. Natl. Acad. Sci. U.S.A.95:3873-3878(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Umbilical vein.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Skin.
7.

"A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting."
Frank D. , Mendelsohn C.L. , Ciccone E. , Svensson K. , Ohlsson R. , Tycko B.
Mamm. Genome10:1150-1159(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
8.

"Retention of imprinting of the human apoptosis-related gene TSSC3 in human brain tumors."
Mueller S. , van den Boom D. , Zirkel D. , Koester H. , Berthold F. , Schwab M. , Westphal M. , Zumkeller W.
Hum. Mol. Genet.9:757-763(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
9.

"The product of the imprinted gene IPL marks human villous cytotrophoblast and is lost in complete hydatidiform mole."
Saxena A. , Frank D. , Panichkul P. , Van den Veyver I.B. , Tycko B. , Thaker H.
Placenta24:835-842(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
10.

"Immunohistochemistry for the imprinted gene product IPL/PHLDA2 for facilitating the differential diagnosis of complete hydatidiform mole."
Thaker H.M. , Berlin A. , Tycko B. , Goldstein D.P. , Berkowitz R.S. , Castrillon D.H. , Genest D.R.
J. Reprod. Med.49:630-636(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
11.

"Complete hydatidiform mole retaining a chromosome 11 of maternal origin: molecular genetic analysis of a case."
Fisher R.A. , Nucci M.R. , Thaker H.M. , Weremowicz S. , Genest D.R. , Castrillon D.H.
Mod. Pathol.17:1155-1160(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;IMPRINTING
12.

"Upregulation of PHLDA2 in Dicer knockdown HEK293 cells."
Tang K.-F. , Wang Y. , Wang P. , Chen M. , Chen Y. , Hu H.-D. , Hu P. , Wang B. , Yang W. , Ren H.
Biochim. Biophys. Acta1770:820-825(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IMPRINTING
13.

"Hypoxia regulates the expression of PHLDA2 in primary term human trophoblasts."
Kim H.-S. , Roh C.-R. , Chen B. , Tycko B. , Nelson D.M. , Sadovsky Y.
Placenta28:77-84(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
14.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-3; SER-141 AND SER-144;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
15.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42; SER-144 AND THR-151;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
16.

"PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt."
Kawase T. , Ohki R. , Shibata T. , Tsutsumi S. , Kamimura N. , Inazawa J. , Ohta T. , Ichikawa H. , Aburatani H. , Tashiro F. , Taya Y.
Cell136:535-550(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LACK OF INDUCTION BY TP53
17.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
18.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
19.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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