Plk1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPlk1 ELISA Kit for Rat(Rattus norvegicus)

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Plk1 (Gene name),

Serine/threonine-protein kinase PLK1 (Protein name ), PLK1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Plk1(Plk);

Protein name:

Serine/threonine-protein kinase PLK1;

Alternative:

Polo-like kinase 1(PLK-1);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with CEP170 and EVI5. Interacts and phosphorylates ERCC6L. Interacts with FAM29A. Interacts with SLX4/BTBD12 and TTDN1. Interacts with BUB1B. Interacts (via POLO-box domain) with the phosphorylated form of BUB1, MLF1IP and CDC25C. Interacts with BORA, KIF2A and AURKA. Interacts with TOPORS and CYLD.

Function:

Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS. Phosphorylates NEDD1. NEDD1 phosphorylation promotes subsequent targeting of the gamma-tubulin ring complex (gTuRC) to the centrosome, an important step for spindle formation.

Subcellular Location:

Nucleus Chromosome centromere kinetochore Cytoplasm cytoskeleton centrosome During early stages of mitosis, the phosphorylated form is detected on centrosomes and kinetochores. Localizes to the outer kinetochore. Presence of SGOL1 and interaction with the phosphorylated form of BUB1 is required for the kinetochore localization.

Protein Attributes:

Sequence length:

603

Sequence:

50:

100:

150:

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300:

350:

400:

450:

500:

550:

600:

603:

KAS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q62673

UniGene:

Rn.11034

KEGG:

rno:25515

Pfam:

PF00069

String:

Q62673

STRING:

10116.ENSRNOP00000025629

Uniprot:

Q62673

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ELISA Kit for Rat Serine/threonine-protein kinase PLK1

Cat.:

E1662h

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96T

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ELISA Kit for Rat Serine/threonine-protein kinase PLK1

Cat.:

E1662m

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96T

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ELISA Kit for Rat Serine/threonine-protein kinase PLK1

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E1662r

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96T

ELISA Kit for Rat Serine/threonine-protein kinase PLK1

Cat.:

E1662b

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96T

CLIA Kit for Rat Serine/threonine-protein kinase PLK1

Cat.:

U1662b

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96T

CLIA Kit for Rat Serine/threonine-protein kinase PLK1

Cat.:

U1662r

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96T

CLIA Kit for Rat Serine/threonine-protein kinase PLK1

Cat.:

U1662m

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96T

CLIA Kit for Rat Serine/threonine-protein kinase PLK1

Cat.:

U1662h

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96T

Polyclonal Antibody for Rat Serine/threonine-protein kinase PLK1

Cat.:

P1662Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Serine/threonine-protein kinase PLK1

Cat.:

P1662Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat Serine/threonine-protein kinase PLK1

Cat.:

P1662Rb-r

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Polyclonal Antibody for Rat Serine/threonine-protein kinase PLK1

Monoclonal Antibody for Rat Serine/threonine-protein kinase PLK1

Protein for Rat Serine/threonine-protein kinase PLK1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

Amstrup J. , Hansen J.A. , Hxirlis Nielsen J.
Submitted (1994-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Pancreas.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.

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