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Index > Protein center > PLG(Gene name) > Human
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  • PLG (Gene name),
  • Plasminogen (Protein name ),  PLMN_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PLG;
    Protein name:
    Plasminogen;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts (both mature PLG and the angiostatin peptide) with CSPG4 and AMOT. Interacts (via the Kringle domains) with HRG; the interaction tethers PLG to the cell surface and enhances its activation.
    Function:
    Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
    Subcellular Location:
    Secreted Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.
    Protein Attributes:
    Sequence length:
    810
    Sequence:
    50:
    MEHKEVVLLL | LLFLKSGQGE | PLDDYVNTQG | ASLFSVTKKQ | LGAGSIEECA | 
    100:
    AKCEEDEEFT | CRAFQYHSKE | QQCVIMAENR | KSSIIIRMRD | VVLFEKKVYL | 
    150:
    SECKTGNGKN | YRGTMSKTKN | GITCQKWSST | SPHRPRFSPA | THPSEGLEEN | 
    200:
    YCRNPDNDPQ | GPWCYTTDPE | KRYDYCDILE | CEEECMHCSG | ENYDGKISKT | 
    250:
    MSGLECQAWD | SQSPHAHGYI | PSKFPNKNLK | KNYCRNPDRE | LRPWCFTTDP | 
    300:
    NKRWELCDIP | RCTTPPPSSG | PTYQCLKGTG | ENYRGNVAVT | VSGHTCQHWS | 
    350:
    AQTPHTHNRT | PENFPCKNLD | ENYCRNPDGK | RAPWCHTTNS | QVRWEYCKIP | 
    400:
    SCDSSPVSTE | QLAPTAPPEL | TPVVQDCYHG | DGQSYRGTSS | TTTTGKKCQS | 
    450:
    WSSMTPHRHQ | KTPENYPNAG | LTMNYCRNPD | ADKGPWCFTT | DPSVRWEYCN | 
    500:
    LKKCSGTEAS | VVAPPPVVLL | PDVETPSEED | CMFGNGKGYR | GKRATTVTGT | 
    550:
    PCQDWAAQEP | HRHSIFTPET | NPRAGLEKNY | CRNPDGDVGG | PWCYTTNPRK | 
    600:
    LYDYCDVPQC | AAPSFDCGKP | QVEPKKCPGR | VVGGCVAHPH | SWPWQVSLRT | 
    650:
    RFGMHFCGGT | LISPEWVLTA | AHCLEKSPRP | SSYKVILGAH | QEVNLEPHVQ | 
    700:
    EIEVSRLFLE | PTRKDIALLK | LSSPAVITDK | VIPACLPSPN | YVVADRTECF | 
    750:
    ITGWGETQGT | FGAGLLKEAQ | LPVIENKVCN | RYEFLNGRVQ | STELCAGHLA | 
    800:
    GGTDSCQGDS | GGPLVCFEKD | KYILQGVTSW | GLGCARPNKP | GVYVRVSRFV | 
    810:
    TWIEGVMRNN | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    SMR:
    UniGene:
    String:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Plasminogen
    Cat.:
    E1236b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Plasminogen
    Cat.:
    E1236h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Plasminogen
    Cat.:
    E1236d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Plasminogen
    Cat.:
    E1236p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Plasminogen
    Cat.:
    E1236r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Plasminogen
    Cat.:
    E1236m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Plasminogen
    Cat.:
    U1236m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Plasminogen
    Cat.:
    U1236r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Plasminogen
    Cat.:
    U1236p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Plasminogen
    Cat.:
    U1236d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Plasminogen
    Cat.:
    U1236b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Plasminogen
    Cat.:
    U1236h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Plasminogen
    Polyclonal Antibody for Human Plasminogen
    Polyclonal Antibody for Human Plasminogen
    Cat.:
    P1236Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Plasminogen
    Polyclonal Antibody for Human Plasminogen
    Cat.:
    P1236Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Plasminogen
    Cat.:
    P1236Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Plasminogen
    Monoclonal Antibody for Human Plasminogen
    Monoclonal Antibody for Human Plasminogen
    Monoclonal Antibody for Human Plasminogen
    Monoclonal Antibody for Human Plasminogen
    Monoclonal Antibody for Human Plasminogen
    Protein for Human Plasminogen
    Protein for Human Plasminogen
    Protein for Human Plasminogen
    Protein for Human Plasminogen
    Protein for Human Plasminogen
    Protein for Human Plasminogen

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of the gene for human plasminogen, a key proenzyme in the fibrinolytic system."
      Petersen T.E. , Martzen M.R. , Ichinose A. , Davie E.W.
      J. Biol. Chem.265:6104-6111(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASN-472
    2. 2.
      "Molecular cloning and characterization of a full-length cDNA clone for human plasminogen."
      Forsgren M. , Raden B. , Israelsson M. , Larsson K. , Heden L.-O.
      FEBS Lett.213:254-260(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Expression of recombinant human plasminogen and aglycoplasminogen in HeLa cells."
      Browne M.J. , Chapman C.G. , Dodd I. , Carey J.E. , Lawrence G.M.P. , Mitchell D. , Robinson J.H.
      Submitted (1991-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    4. 4.
      SeattleSNPs variation discovery resource
      Submitted (2002-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LYS-57; GLN-133; HIS-261; TRP-408; ASN-472; VAL-494 AND TRP-523
    5. 5.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASP-676
      tissue: Kidney.
    7. 7.
      Sottrup-Jensen L. , Petersen T.E. , Magnusson S.
      Submitted (1977-07) to the PIR data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-810;VARIANT ASN-472
    8. 8.
      "Structural relationship between 'glutamic acid' and 'lysine' forms of human plasminogen and their interaction with the NH2-terminal activation peptide as studied by affinity chromatography."
      Wiman B. , Wallen P.
      Eur. J. Biochem.50:489-494(1975) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-100
    9. 9.
      "The primary structure of human plasminogen."
      Sottrup-Jensen L. , Claeys H. , Zajdel M. , Petersen T.E. , Magnusson S.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 95-580; 581-626; 657-700 AND 732-810;VARIANT ASN-472
    10. 10.
      "Characterization of a complementary deoxyribonucleic acid coding for human and bovine plasminogen."
      Malinowski D.P. , Sadler J.E. , Davie E.W.
      Biochemistry23:4243-4250(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 292-810
    11. 11.
      "Amino-acid sequence of the cyanogen-bromide fragment from human plasminogen that forms the linkage between the plasmin chains."
      Wiman B. , Wallen P.
      Eur. J. Biochem.58:539-547(1975) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 483-604
    12. 12.
      "Primary structure of the B-chain of human plasmin."
      Wiman B.
      Eur. J. Biochem.76:129-137(1977) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 581-810
    13. 13.
      "The primary structure of human plasminogen. II. The histidine loop of human plasmin: light (B) chain active center histidine sequence."
      Robbins K.C. , Bernabe P. , Arzadon L. , Summaria L.
      J. Biol. Chem.248:1631-1633(1973) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACTIVE SITE
    14. 14.
      "Studies on the active center of human plasmin. Partial amino acid sequence of a peptide containing the active center serine residue."
      Groskopf W.R. , Summaria L. , Robbins K.C.
      J. Biol. Chem.244:3590-3597(1969) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACTIVE SITE
    15. 15.
      "Structure of the omega-aminocarboxylic acid-binding sites of human plasminogen. Arginine 70 and aspartic acid 56 are essential for binding of ligand by kringle 4."
      Trexler M. , Vali Z. , Patthy L.
      J. Biol. Chem.257:7401-7406(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: OMEGA-AMINOCARBOXYLIC ACID-BINDING SITES
    16. 16.
      "The fibrin-binding site of human plasminogen. Arginines 32 and 34 are essential for fibrin affinity of the kringle 1 domain."
      Vali Z. , Patthy L.
      J. Biol. Chem.259:13690-13694(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FIBRIN AND OMEGA-AMINOCARBOXYLIC ACID BINDING SITES
    17. 17.
      "Serine-578 is a major phosphorylation locus in human plasma plasminogen."
      Wang H. , Prorok M. , Bretthauer R.K. , Castellino F.J.
      Biochemistry36:8100-8106(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-597
    18. 18.
      "The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns."
      Marti T. , Schaller J. , Rickli E.E. , Schmid K. , Kamerling J.P. , Gerwig G.J. , van Halbeek H. , Vliegenthart J.F.G.
      Eur. J. Biochem.173:57-63(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT SER-268; ASN-308 AND THR-365;STRUCTURE OF CARBOHYDRATES
    19. 19.
      "Acceleration of plasminogen activation by tissue plasminogen activator on surface-bound histidine-proline-rich glycoprotein."
      Borza D.B. , Morgan W.T.
      J. Biol. Chem.272:5718-5726(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HRG
    20. 20.
      "Evidence for a novel O-linked sialylated trisaccharide on Ser-248 of human plasminogen 2."
      Pirie-Shepherd S.R. , Stevens R.D. , Andon N.L. , Enghild J.J. , Pizzo S.V.
      J. Biol. Chem.272:7408-7411(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT SER-268
    21. 21.
      "Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma."
      O'Reilly M.S. , Holmgren L. , Shing Y. , Chen C. , Rosenthal R.A. , Moses M. , Lane W.S. , Cao Y. , Sage E.H. , Folkman J.
      Cell79:315-328(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF ANGIOSTATIN;PARTIAL PROTEIN SEQUENCE
    22. 22.
      "A recombinant human angiostatin protein inhibits experimental primary and metastatic cancer."
      Sim B.K. , O'Reilly M.S. , Liang H. , Fortier A.H. , He W. , Madsen J.W. , Lapcevich R. , Nacy C.A.
      Cancer Res.57:1329-1334(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF ANGIOSTATIN
    23. 23.
      "Generation of an angiostatin-like fragment from plasminogen by stromelysin-1 (MMP-3)."
      Lijnen H.R. , Ugwu F. , Bini A. , Collen D.
      Biochemistry37:4699-4702(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC CLEAVAGE
    24. 24.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATP5A1;SUBCELLULAR LOCATION
    25. 25.
      "Binding of the NG2 proteoglycan to kringle domains modulates the functional properties of angiostatin and plasmin(ogen)."
      Goretzki L. , Lombardo C.R. , Stallcup W.B.
      J. Biol. Chem.275:28625-28633(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CSPG4;DOMAIN
    26. 26.
      "Protease nexin-1 inhibits plasminogen activation-induced apoptosis of adherent cells."
      Rossignol P. , Ho-Tin-Noe B. , Vranckx R. , Bouton M.C. , Meilhac O. , Lijnen H.R. , Guillin M.C. , Michel J.B. , Angles-Cano E.
      J. Biol. Chem.279:10346-10356(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING;ENZYME REGULATION;SUBCELLULAR LOCATION;FUNCTION OF PLASMIN;MUTAGENESIS OF SER-741
    27. 27.
      "Angiomotin regulates endothelial cell-cell junctions and cell motility."
      Bratt A. , Birot O. , Sinha I. , Veitonmaeki N. , Aase K. , Ernkvist M. , Holmgren L.
      J. Biol. Chem.280:34859-34869(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AMOT
    28. 28.
      "Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry."
      Picariello G. , Ferranti P. , Mamone G. , Roepstorff P. , Addeo F.
      Proteomics8:3833-3847(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-308
      tissue: Milk.
    29. 29.
      "A unique proteolytic fragment of human fibrinogen containing the A alpha COOH-terminal domain of the native molecule."
      Kirschbaum N.E. , Budzynski A.Z.
      J. Biol. Chem.265:13669-13676(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY
    30. 30.
      "Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage."
      Poon I.K. , Olsson A.K. , Hulett M.D. , Parish C.R.
      Biochem. J.424:27-37(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HRG
    31. 31.
      "Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-A resolution."
      Mulichak A.M. , Tulinsky A. , Ravichandran K.G.
      Biochemistry30:10576-10588(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 374-461
    32. 32.
      "The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4."
      Wu T.-P. , Padmanabhan K. , Tulinsky A. , Mulichak A.M.
      Biochemistry30:10589-10594(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS) OF 374-461
    33. 33.
      "The structure of recombinant plasminogen kringle 1 and the fibrin binding site."
      Wu T.-P. , Padmanabhan K.P. , Tulinsky A.
      Blood Coagul. Fibrinolysis5:157-166(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.48 ANGSTROMS) OF 101-181
    34. 34.
      "Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid."
      Mathews I.I. , Vanderhoff-Hanaver P. , Castellino F.J. , Tulinsky A.
      Biochemistry35:2567-2576(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 102-181
    35. 35.
      "Structure of human plasminogen kringle 4 at 1.68 Angstrom and 277 K. A possible structural role of disordered residues."
      Stec B. , Yamano A. , Whitlow M. , Teeter M.M.
      Acta Crystallogr. D53:169-178(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.67 ANGSTROMS) OF 376-454
    36. 36.
      "The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action."
      Parry M.A. , Fernandez-Catalan C. , Bergner A. , Huber R. , Hopfner K.P. , Schlott B. , Guehrs K.H. , Bode W.
      Nat. Struct. Biol.5:917-923(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS) OF 561-810;DISULFIDE BONDS
    37. 37.
      "Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen."
      Chang Y. , Mochalkin I. , McCance S.G. , Cheng B. , Tulinsky A. , Castellino F.J.
      Biochemistry37:3258-3271(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.66 ANGSTROMS) OF 480-563
    38. 38.
      "Human plasminogen catalytic domain undergoes an unusual conformational change upon activation."
      Wang X. , Terzyan S. , Tang J. , Loy J.A. , Lin X. , Zhang X.C.
      J. Mol. Biol.295:903-914(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 564-810;DISULFIDE BONDS
    39. 39.
      "Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein."
      Rios-Steiner J.L. , Schenone M. , Mochalkin I. , Tulinsky A. , Castellino F.J.
      J. Mol. Biol.308:705-719(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 183-262
    40. 40.
      "The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin."
      Abad M.C. , Arni R.K. , Grella D.K. , Castellino F.J. , Tulinsky A. , Geiger J.H.
      J. Mol. Biol.318:1009-1017(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 100-352;DISULFIDE BONDS
    41. 41.
      "Effects of deletion of streptokinase residues 48-59 on plasminogen activation."
      Wakeham N. , Terzyan S. , Zhai P. , Loy J.A. , Tang J. , Zhang X.C.
      Protein Eng.15:753-761(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 562-810
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      "Characterization of Lys-698-to-Met substitution in human plasminogen catalytic domain."
      Terzyan S. , Wakeham N. , Zhai P. , Rodgers K. , Zhang X.C.
      Proteins56:277-284(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 564-810
    43. 43.
      "The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake."
      Millers E.K. , Johnson L.A. , Birrell G.W. , Masci P.P. , Lavin M.F. , de Jersey J. , Guddat L.W.
      PLoS ONE8:E54104-E54104(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.78 ANGSTROMS) OF 564-810 IN COMPLEX WITH THE SNAKE VENOM PROTEASE INHIBITOR TEXTILININ-1;DISULFIDE BOND
    44. 44.
      "Solution structure of the kringle 4 domain from human plasminogen by 1H nuclear magnetic resonance spectroscopy and distance geometry."
      Atkinson R.A. , Williams R.J.P.
      J. Mol. Biol.212:541-552(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 374-461
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      "1H-NMR assignments and secondary structure of human plasminogen kringle 1."
      Rejante M.R. , Llinas M.
      Eur. J. Biochem.221:927-937(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 96-184
    46. 46.
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      Rejante M.R. , Llinas M.
      Eur. J. Biochem.221:939-949(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 96-184
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      "Recombinant gene expression and 1H NMR characteristics of the kringle (2 + 3) supermodule: spectroscopic/functional individuality of plasminogen kringle domains."
      Soehndel S. , Hu C.-K. , Marti D. , Affolter M. , Schaller J. , Llinas M. , Rickli E.E.
      Biochemistry35:2357-2364(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 183-354
    48. 48.
      "Ligand preferences of kringle 2 and homologous domains of human plasminogen: canvassing weak, intermediate, and high-affinity binding sites by 1H-NMR."
      Marti D.N. , Hu C.K. , An S.S. , von Haller P. , Schaller J. , Llinas M.
      Biochemistry36:11591-11604(1997) [PubMed] [Europe PMC] [Abstract]
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    49. 49.
      "Two types of abnormal genes for plasminogen in families with a predisposition for thrombosis."
      Ichinose A. , Espling E.S. , Takamatsu J. , Saito H. , Shinmyozu K. , Maruyama I. , Petersen T.E. , Davie E.W.
      Proc. Natl. Acad. Sci. U.S.A.88:115-119(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PLGD PHE-374 AND THR-620
    50. 50.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
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      Azuma H. , Uno Y. , Shigekiyo T. , Saito S.
      Blood82:475-480(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PLGD PRO-591
    52. 52.
      "Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site."
      Miyata T. , Iwanaga S. , Sakata Y. , Aoki N.
      Proc. Natl. Acad. Sci. U.S.A.79:6132-6136(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PLGD THR-620
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      "Plasminogens Tochigi II and Nagoya: two additional molecular defects with Ala-600-->Thr replacement found in plasmin light chain variants."
      Miyata T. , Iwanaga S. , Sakata Y. , Aoki N. , Takamatsu J. , Kamiya T.
      J. Biochem.96:277-287(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PLGD THR-620
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      "Plasminogen with type-I mutation is polymorphic in the Japanese population."
      Kikuchi S. , Yamanouchi Y. , Li L. , Kobayashi K. , Ijima H. , Miyazaki R. , Tsuchiya S. , Hamaguchi H.
      Hum. Genet.90:7-11(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PLGD THR-620
    55. 55.
      "Homozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis."
      Schuster V. , Mingers A.-M. , Seidenspinner S. , Nuessgens Z. , Pukrop T. , Kreth H.W.
      Blood90:958-966(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PLGD HIS-235
    56. 56.
      "Plasminogen Kanagawa-I, a novel missense mutation, is caused by the amino acid substitution G732R."
      Higuchi Y. , Furihata K. , Ueno I. , Ishikawa S. , Okumura N. , Tozuka M. , Sakurai N.
      Br. J. Haematol.103:867-870(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PLGD ARG-751
    57. 57.
      "Compound-heterozygous mutations in the plasminogen gene predispose to the development of ligneous conjunctivitis."
      Schuster V. , Seidenspinner S. , Zeitler P. , Escher C. , Pleyer U. , Bernauer W. , Stiehm E.R. , Isenberg S. , Seregard S. , Olsson T. , Mingers A.-M. , Schambeck C. , Kreth H.W.
      Blood93:3457-3466(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PLGD GLU-38; PRO-147 AND HIS-532
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