POU2F2 ELISA Kit for Human(Homo sapiens) | EIAab.comPOU2F2 ELISA Kit for Human(Homo sapiens)

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POU2F2 (Gene name),

POU domain, class 2, transcription factor 2 (Protein name ), PO2F2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

POU2F2(OCT2;OTF2);

Protein name:

POU domain, class 2, transcription factor 2;

Alternative:

Octamer-binding protein 2(Oct-2);Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2;Octamer-binding transcription factor 2(OTF-2);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with NR3C1, AR and PGR.

Function:

Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

479

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

479:

QGSHSAIGLS | GLNPSTGPGL | WWNPAPYQP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

164176

UniGene:

Hs.654420

KEGG:

hsa:5452

String:

P09086

SMR:

P09086

Pfam:

PF00046

UniGene:

Hs.147381

STRING:

9606.ENSP00000373992

Uniprot:

P09086

FOR

ELISA Kit for Human POU domain, class 2, transcription factor 2

Cat.:

E1527h

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Manual:

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Packing:

96T

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ELISA Kit for Human POU domain, class 2, transcription factor 2

Cat.:

E1527p

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human POU domain, class 2, transcription factor 2

Cat.:

E1527m

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MSDS:

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Packing:

96T

CLIA Kit for Human POU domain, class 2, transcription factor 2

Cat.:

U1527h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human POU domain, class 2, transcription factor 2

Cat.:

U1527p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human POU domain, class 2, transcription factor 2

Cat.:

U1527m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human POU domain, class 2, transcription factor 2

Cat.:

P1527Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human POU domain, class 2, transcription factor 2

Cat.:

P1527Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human POU domain, class 2, transcription factor 2

Protein for Human POU domain, class 2, transcription factor 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains."
Clerc R.G. , Corcoran L.M. , Lebowitz J.H. , Baltimore D. , Sharp P.A.
Genes Dev.2:1570-1581(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [MRNA] OF 450-479 (ISOFORM 1)
2.

"A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein."
Scheidereit C. , Cromlish J.A. , Gerster T. , Kawakami K. , Balmaceda C.-G. , Currie R.A. , Roder R.G.
Nature336:551-557(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION;TISSUE SPECIFICITY
tissue: B-cell lymphoma.
3.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
tissue: Lymph.
5.

"A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells."
Mueller M.M. , Ruppert S. , Schaffner W. , Matthias P.
Nature336:544-551(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-479 (ISOFORM 1)
tissue: B-cell.
6.

"Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells."
Muller-Immergluck M.M. , Schaffner W. , Matthias P.
EMBO J.9:1625-1634(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 99-161;FUNCTION
7.

"Short introns interrupting the Oct-2 POU domain may prevent recombination between POU family genes without interfering with potential POU domain 'shuffling' in evolution."
Matsuo K. , Clay O. , Kuenzler P. , Georgiev O. , Urbanek P. , Schaffner W.
Biol. Chem. Hoppe-Seyler375:675-683(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 168-377
8.

"A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain."
Ko H.-S. , Fast P. , McBride W. , Staudt L.M.
Cell55:135-144(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 240-387;FUNCTION
9.

"Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter."
Tanaka M. , Lai J.-S. , Herr W.
Cell68:755-767(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 468-479 (ISOFORM 5);FUNCTION
10.

"Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA)."
Schreiber E. , Matthias P. , Mueller M.M. , Schaffner W.
EMBO J.7:4221-4229(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION (ISOFORM 5);TISSUE SPECIFICITY
11.

"Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoter."
Prefontaine G.G. , Walther R. , Giffin W. , Lemieux M.E. , Pope L. , Hache R.J.G.
J. Biol. Chem.274:26713-26719(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NR3C1; AR AND PGR
12.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"Solution structure of a POU-specific homeodomain: 3D-NMR studies of human B-cell transcription factor Oct-2."
Sivaraja M. , Botfield M.C. , Mueller M. , Jancso A. , Weiss M.A.
Biochemistry33:9845-9855(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 297-359

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