ACP5 ELISA Kit for Human(Homo sapiens) | EIAab.comACP5 ELISA Kit for Human(Homo sapiens)

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ACP5 (Gene name),

Tartrate-resistant acid phosphatase type 5 (Protein name ), PPA5_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ACP5;

Protein name:

Tartrate-resistant acid phosphatase type 5(TR-AP);

Alternative:

Type 5 acid phosphatase;Tartrate-resistant acid ATPase(TrATPase);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).

Function:

Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.

Subcellular Location:

Lysosome

Protein Attributes:

Sequence length:

325

Sequence:

50:

100:

150:

200:

250:

300:

325:

EMTVTYIEAS | GKSLFKTRLP | RRARP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.1211

Pfam:

PF00149

SMR:

P13686

MIM:

171640

STRING:

9606.ENSP00000218758

KEGG:

hsa:54

String:

P13686

Uniprot:

P13686

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ELISA Kit for Human TR-AP

Cat.:

E0902h

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96T

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ELISA Kit for Human TR-AP

Cat.:

E0902m

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96T

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ELISA Kit for Human TR-AP

Cat.:

E0902r

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96T

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ELISA Kit for Human TR-AP

Cat.:

E0902p

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96T

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ELISA Kit for Human TR-AP

MSDS:

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CLIA Kit for Human TR-AP

Cat.:

U0902h

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Packing:

96T

CLIA Kit for Human TR-AP

Cat.:

U0902p

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human TR-AP

MSDS:

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CLIA Kit for Human TR-AP

Cat.:

U0902m

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MSDS:

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Packing:

96T

CLIA Kit for Human TR-AP

Cat.:

U0902r

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Packing:

96T

Polyclonal Antibody for Human TR-AP

Cat.:

P0902Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human TR-AP

Cat.:

P0902Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human TR-AP

Cat.:

P0902Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human TR-AP

Monoclonal Antibody for Human TR-AP

Protein for Human TR-AP

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular cloning of the type 5, iron-containing, tartrate-resistant acid phosphatase from human placenta."
Ketcham C.M. , Roberts R.M. , Simmen R.C.M. , Nick H.S.
J. Biol. Chem.264:557-563(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Placenta.
2.

"Type 5 acid phosphatase. Sequence, expression and chromosomal localization of a differentiation-associated protein of the human macrophage."
Lord D.K. , Cross N.C.P. , Bevilacqua M.A. , Roder S.H. , Gorman P.A. , Groves A.V. , Moss D.W. , Sheer D. , Cox T.M.
Eur. J. Biochem.189:287-293(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Placenta.
3.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS MET-148 AND MET-200
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Skin.
6.

"Isolation and characterization of the genes encoding mouse and human type-5 acid phosphatase."
Cassady A.I. , King A.G. , Cross N.C.P. , Hume D.A.
Gene130:201-207(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-245
7.

"Purification and characterization of a tartrate-resistant acid phosphatase from human osteoclastomas."
Hayman A.R. , Warburton M.J. , Pringle J.A.S. , Coles B. , Chambers T.J.
Biochem. J.261:601-609(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-64 AND 183-202
tissue: Osteoclastoma.
8.

"Heterogeneity of hairy cell tartrate-resistant acid phosphatase."
Janckila A.J. , Latham M.D. , Lam K.-W. , Chow K.-C. , Li C.-Y. , Yam L.T.
Clin. Biochem.25:437-443(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-55 AND 183-203;SUBUNIT
tissue: Spleen.
9.

"Purification and N-terminal sequence of two tartrate-resistant acid phosphatases type-5 from the hairy cell leukemia spleen."
Stepan J.J. , Lau K.H.W. , Mohan S. , Kraenzlin M. , Baylink D.J.
Biochem. Biophys. Res. Commun.165:1027-1034(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-37
tissue: Osteoclastoma.
10.

"Purification and N-terminal amino acid sequence of the tartrate-resistant acid phosphatase from human osteoclastoma: evidence for a single structure."
Stepan J.J. , Lau K.H.W. , Mohan S. , Singer F.R. , Baylink D.J.
Biochem. Biophys. Res. Commun.168:792-800(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-31
tissue: Osteoclastoma.
11.

"Tartrate-resistant acid phosphatase from human osteoclastomas is translated as a single polypeptide."
Hayman A.R. , Dryden A.J. , Chambers T.J. , Warburton M.J.
Biochem. J.277:631-634(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
12.

"Crystal structures of recombinant human purple acid phosphatase with and without an inhibitory conformation of the repression loop."
Straeter N. , Jasper B. , Scholte M. , Krebs B. , Duff A.P. , Langley D.B. , Han R. , Averill B.A. , Freeman H.C. , Guss J.M.
J. Mol. Biol.351:233-246(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 22-325 IN COMPLEX WITH IRON IONS;GLYCOSYLATION AT ASN-116
13.

"Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature."
Briggs T.A. , Rice G.I. , Daly S. , Urquhart J. , Gornall H. , Bader-Meunier B. , Baskar K. , Baskar S. , Baudouin V. , Beresford M.W. , Black G.C. , Dearman R.J. , de Zegher F. , Foster E.S. , Frances C. , Hayman A.R. , Hilton E. , Job-Deslandre C. , more...
Nat. Genet.43:127-131(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SPENCDI ILE-89; ARG-215; ASN-241 AND LYS-264
14.

"Genetic deficiency of tartrate-resistant acid phosphatase associated with skeletal dysplasia, cerebral calcifications and autoimmunity."
Lausch E. , Janecke A. , Bros M. , Trojandt S. , Alanay Y. , De Laet C. , Hubner C.A. , Meinecke P. , Nishimura G. , Matsuo M. , Hirano Y. , Tenoutasse S. , Kiss A. , Rosa R.F. , Unger S.L. , Renella R. , Bonafe L. , Spranger J. , more...
Nat. Genet.43:132-137(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SPENCDI MET-52; ARG-109; PRO-201; ARG-215; HIS-262; LYS-264 AND TYR-278 DEL

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