"cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor."
Sher T. , Yi H.F. , McBride O.W. , Gonzales F.J.
Biochemistry32:5598-5604(1993) [PubMed] [Europe PMC] [Abstract]

"Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators."
Mukherjee R. , Jow L. , Noonan D. , McDonnell D.P.
J. Steroid Biochem. Mol. Biol.51:157-166(1994) [PubMed] [Europe PMC] [Abstract]

"Peroxisome proliferator-activated receptors: structures and function."
Tugwood J.D. , Aldridge T.C. , Lambe K.G. , Macdonald N. , Woodyatt N.J.
Ann. N. Y. Acad. Sci.804:252-265(1996) [PubMed] [Europe PMC] [Abstract]

"DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system."
Kobayashi T. , Kodani Y. , Nozawa A. , Endo Y. , Sawasaki T.
FEBS Lett.582:2737-2744(2008) [PubMed] [Europe PMC] [Abstract]

"Optimization of an enzyme-linked immunosorbent assay to screen ligand of Peroxisome proliferator-activated receptor alpha."
Cho M.-C. , Lee S. , Choi H.S. , Yang Y. , Tae Hong J. , Kim S.J. , Yoon D.-Y.
Immunopharmacol. Immunotoxicol.31:459-467(2009) [PubMed] [Europe PMC] [Abstract]

"A novel alternatively spliced peroxisome proliferator-activated receptor alpha."
Jiang Y. , Xie Z. , Liu H. , Liu M. , Liu F.
Submitted (2008-01) to the EMBL/GenBank/DDBJ databases

"A genome annotation-driven approach to cloning the human ORFeome."
Collins J.E. , Wright C.L. , Edwards C.A. , Davis M.P. , Grinham J.A. , Cole C.G. , Goward M.E. , Aguado B. , Mallya M. , Mokrab Y. , Huckle E.J. , Beare D.M. , Dunham I.
Genome Biol.5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , Yamamoto J. , Saito K. , Kawai Y. , Isono Y. , Nakamura Y. , Nagahari K. , Murakami K. , Yasuda T. , Iwayanagi T. , Wagatsuma M. , Shiratori A. , Sudo H. , Hosoiri T. , Kaku Y. , Kodaira H. , Kondo H. , Sugawara M. , Takahashi M. , Kanda K. , Yokoi T. , Furuya T. , Kikkawa E. , Omura Y. , Abe K. , Kamihara K. , Katsuta N. , Sato K. , Tanikawa M. , Yamazaki M. , Ninomiya K. , Ishibashi T. , Yamashita H. , Murakawa K. , Fujimori K. , Tanai H. , Kimata M. , Watanabe M. , Hiraoka S. , Chiba Y. , Ishida S. , Ono Y. , Takiguchi S. , Watanabe S. , Yosida M. , Hotuta T. , Kusano J. , Kanehori K. , Takahashi-Fujii A. , Hara H. , Tanase T.-O. , Nomura Y. , Togiya S. , Komai F. , Hara R. , Takeuchi K. , Arita M. , Imose N. , Musashino K. , Yuuki H. , Oshima A. , Sasaki N. , Aotsuka S. , Yoshikawa Y. , Matsunawa H. , Ichihara T. , Shiohata N. , Sano S. , Moriya S. , Momiyama H. , Satoh N. , Takami S. , Terashima Y. , Suzuki O. , Nakagawa S. , Senoh A. , Mizoguchi H. , Goto Y. , Shimizu F. , Wakebe H. , Hishigaki H. , Watanabe T. , Sugiyama A. , Takemoto M. , Kawakami B. , Yamazaki M. , Watanabe K. , Kumagai A. , Itakura S. , Fukuzumi Y. , Fujimori Y. , Komiyama M. , Tashiro H. , Tanigami A. , Fujiwara T. , Ono T. , Yamada K. , Fujii Y. , Ozaki K. , Hirao M. , Ohmori Y. , Kawabata A. , Hikiji T. , Kobatake N. , Inagaki H. , Ikema Y. , Okamoto S. , Okitani R. , Kawakami T. , Noguchi S. , Itoh T. , Shigeta K. , Senba T. , Matsumura K. , Nakajima Y. , Mizuno T. , Morinaga M. , Sasaki M. , Togashi T. , Oyama M. , Hata H. , Watanabe M. , Komatsu T. , Mizushima-Sugano J. , Satoh T. , Shirai Y. , Takahashi Y. , Nakagawa K. , Okumura K. , Nagase T. , Nomura N. , Kikuchi H. , Masuho Y. , Yamashita R. , Nakai K. , Yada T. , Nakamura Y. , Ohara O. , Isogai T. , Sugano S. more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

SeattleSNPs variation discovery resource
Submitted (2002-12) to the EMBL/GenBank/DDBJ databases

"The DNA sequence of human chromosome 22."
Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , Buck D. , Burgess J. , Burrill W.D. , Burton J. , Carder C. , Carter N.P. , Chen Y. , Clark G. , Clegg S.M. , Cobley V.E. , Cole C.G. , Collier R.E. , Connor R. , Conroy D. , Corby N.R. , Coville G.J. , Cox A.V. , Davis J. , Dawson E. , Dhami P.D. , Dockree C. , Dodsworth S.J. , Durbin R.M. , Ellington A.G. , Evans K.L. , Fey J.M. , Fleming K. , French L. , Garner A.A. , Gilbert J.G.R. , Goward M.E. , Grafham D.V. , Griffiths M.N.D. , Hall C. , Hall R.E. , Hall-Tamlyn G. , Heathcott R.W. , Ho S. , Holmes S. , Hunt S.E. , Jones M.C. , Kershaw J. , Kimberley A.M. , King A. , Laird G.K. , Langford C.F. , Leversha M.A. , Lloyd C. , Lloyd D.M. , Martyn I.D. , Mashreghi-Mohammadi M. , Matthews L.H. , Mccann O.T. , Mcclay J. , Mclaren S. , McMurray A.A. , Milne S.A. , Mortimore B.J. , Odell C.N. , Pavitt R. , Pearce A.V. , Pearson D. , Phillimore B.J.C.T. , Phillips S.H. , Plumb R.W. , Ramsay H. , Ramsey Y. , Rogers L. , Ross M.T. , Scott C.E. , Sehra H.K. , Skuce C.D. , Smalley S. , Smith M.L. , Soderlund C. , Spragon L. , Steward C.A. , Sulston J.E. , Swann R.M. , Vaudin M. , Wall M. , Wallis J.M. , Whiteley M.N. , Willey D.L. , Williams L. , Williams S.A. , Williamson H. , Wilmer T.E. , Wilming L. , Wright C.L. , Hubbard T. , Bentley D.R. , Beck S. , Rogers J. , Shimizu N. , Minoshima S. , Kawasaki K. , Sasaki T. , Asakawa S. , Kudoh J. , Shintani A. , Shibuya K. , Yoshizaki Y. , Aoki N. , Mitsuyama S. , Roe B.A. , Chen F. , Chu L. , Crabtree J. , Deschamps S. , Do A. , Do T. , Dorman A. , Fang F. , Fu Y. , Hu P. , Hua A. , Kenton S. , Lai H. , Lao H.I. , Lewis J. , Lewis S. , Lin S.-P. , Loh P. , Malaj E. , Nguyen T. , Pan H. , Phan S. , Qi S. , Qian Y. , Ray L. , Ren Q. , Shaull S. , Sloan D. , Song L. , Wang Q. , Wang Y. , Wang Z. , White J. , Willingham D. , Wu H. , Yao Z. , Zhan M. , Zhang G. , Chissoe S. , Murray J. , Miller N. , Minx P. , Fulton R. , Johnson D. , Bemis G. , Bentley D. , Bradshaw H. , Bourne S. , Cordes M. , Du Z. , Fulton L. , Goela D. , Graves T. , Hawkins J. , Hinds K. , Kemp K. , Latreille P. , Layman D. , Ozersky P. , Rohlfing T. , Scheet P. , Walker C. , Wamsley A. , Wohldmann P. , Pepin K. , Nelson J. , Korf I. , Bedell J.A. , Hillier L.W. , Mardis E. , Waterston R. , Wilson R. , Emanuel B.S. , Shaikh T. , Kurahashi H. , Saitta S. , Budarf M.L. , McDermid H.E. , Johnson A. , Wong A.C.C. , Morrow B.E. , Edelmann L. , Kim U.J. , Shizuya H. , Simon M.I. , Dumanski J.P. , Peyrard M. , Kedra D. , Seroussi E. , Fransson I. , Tapia I. , Bruder C.E. , O'Brien K.P. , Wilkinson P. , Bodenteich A. , Hartman K. , Hu X. , Khan A.S. , Lane L. , Tilahun Y. , Wright H. more...
Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , Yooseph S. , Lu F. , Nusskern D.R. , Shue B.C. , Zheng X.H. , Zhong F. , Delcher A.L. , Huson D.H. , Kravitz S.A. , Mouchard L. , Reinert K. , Remington K.A. , Clark A.G. , Waterman M.S. , Eichler E.E. , Adams M.D. , Hunkapiller M.W. , Myers E.W. , Venter J.C. more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

"Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for retinoid X receptor. Possible role of a leucine zipper-like heptad repeat."
Juge-Aubry C.E. , Gorla-Bajszczak A. , Pernin A. , Lemberger T. , Wahli W. , Burger A.G. , Meier C.A.
J. Biol. Chem.270:18117-18122(1995) [PubMed] [Europe PMC] [Abstract]

"RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2."
Li H. , Gomes P.J. , Chen J.D.
Proc. Natl. Acad. Sci. U.S.A.94:8479-8484(1997) [PubMed] [Europe PMC] [Abstract]

"Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4."
Yan Z.H. , Karam W.G. , Staudinger J.L. , Medvedev A. , Ghanayem B.I. , Jetten A.M.
J. Biol. Chem.273:10948-10957(1998) [PubMed] [Europe PMC] [Abstract]

"Conserved amino acids in the ligand-binding and tau(i) domains of the peroxisome proliferator-activated receptor alpha are necessary for heterodimerization with RXR."
Gorla-Bajszczak A. , Juge-Aubry C. , Pernin A. , Burger A.G. , Meier C.A.
Mol. Cell. Endocrinol.147:37-47(1999) [PubMed] [Europe PMC] [Abstract]

"Cloning and characterization of RAP250, a nuclear receptor coactivator."
Caira F. , Antonson P. , Pelto-Huikko M. , Treuter E. , Gustafsson J.-A.
J. Biol. Chem.275:5308-5317(2000) [PubMed] [Europe PMC] [Abstract]

"Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity."
Tsutsumi T. , Suzuki T. , Shimoike T. , Suzuki R. , Moriya K. , Shintani Y. , Fujie H. , Matsuura Y. , Koike K. , Miyamura T.
Hepatology35:937-946(2002) [PubMed] [Europe PMC] [Abstract]

"Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha."
Fu J. , Gaetani S. , Oveisi F. , Lo Verme J. , Serrano A. , Rodriguez De Fonseca F. , Rosengarth A. , Luecke H. , Di Giacomo B. , Tarzia G. , Piomelli D.
Nature425:90-93(2003) [PubMed] [Europe PMC] [Abstract]

"Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}."
Park U.H. , Yoon S.K. , Park T. , Kim E.J. , Um S.J.
J. Biol. Chem.286:1354-1363(2011) [PubMed] [Europe PMC] [Abstract]

"Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors."
Xu H.E. , Lambert M.H. , Montana V.G. , Plunket K.D. , Moore L.B. , Collins J.L. , Oplinger J.A. , Kliewer S.A. , Gampe R.T. Jr. , McKee D.D. , Moore J.T. , Willson T.M.
Proc. Natl. Acad. Sci. U.S.A.98:13919-13924(2001) [PubMed] [Europe PMC] [Abstract]

"Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family."
Cronet P. , Petersen J.F.W. , Folmer R. , Blomberg N. , Sjoeblom K. , Karlsson U. , Lindstedt E.-L. , Bamberg K.
Structure9:699-706(2001) [PubMed] [Europe PMC] [Abstract]

"Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha."
Xu H.E. , Stanley T.B. , Montana V.G. , Lambert M.H. , Shearer B.G. , Cobb J.E. , McKee D.D. , Galardi C.M. , Plunket K.D. , Nolte R.T. , Parks D.J. , Moore J.T. , Kliewer S.A. , Willson T.M. , Stimmel J.B.
Nature415:813-817(2002) [PubMed] [Europe PMC] [Abstract]

"Design and synthesis of oxime ethers of alpha-acyl-beta-phenylpropanoic acids as PPAR dual agonists."
Oon Han H. , Kim S.H. , Kim K.-H. , Hur G.-C. , Joo Yim H. , Chung H.-K. , Ho Woo S. , Dong Koo K. , Lee C.-S. , Sung Koh J. , Kim G.T.
Bioorg. Med. Chem. Lett.17:937-941(2007) [PubMed] [Europe PMC] [Abstract]

"Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agents."
Sierra M.L. , Beneton V. , Boullay A.-B. , Boyer T. , Brewster A.G. , Donche F. , Forest M.-C. , Fouchet M.-H. , Gellibert F.J. , Grillot D.A. , Lambert M.H. , Laroze A. , Le Grumelec C. , Linget J.M. , Montana V.G. , Nguyen V.-L. , Nicodeme E. , Patel V. , Penfornis A. , Pineau O. , Pohin D. , Potvain F. , Poulain G. , Ruault C.B. , Saunders M. , Toum J. , Xu H.E. , Xu R.X. , Pianetti P.M. more...
J. Med. Chem.50:685-695(2007) [PubMed] [Europe PMC] [Abstract]

"Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures."
Oyama T. , Toyota K. , Waku T. , Hirakawa Y. , Nagasawa N. , Kasuga J.I. , Hashimoto Y. , Miyachi H. , Morikawa K.
Acta Crystallogr. D65:786-795(2009) [PubMed] [Europe PMC] [Abstract]

"Aleglitazar, a new, potent, and balanced dual PPARalpha/gamma agonist for the treatment of type II diabetes."
Benardeau A. , Benz J. , Binggeli A. , Blum D. , Boehringer M. , Grether U. , Hilpert H. , Kuhn B. , Maerki H.P. , Meyer M. , Puentener K. , Raab S. , Ruf A. , Schlatter D. , Mohr P.
Bioorg. Med. Chem. Lett.19:2468-2473(2009) [PubMed] [Europe PMC] [Abstract]

"Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent."
Artis D.R. , Lin J.J. , Zhang C. , Wang W. , Mehra U. , Perreault M. , Erbe D. , Krupka H.I. , England B.P. , Arnold J. , Plotnikov A.N. , Marimuthu A. , Nguyen H. , Will S. , Signaevsky M. , Kral J. , Cantwell J. , Settachatgull C. , Yan D.S. , Fong D. , Oh A. , Shi S. , Womack P. , Powell B. , Habets G. , West B.L. , Zhang K.Y.J. , Milburn M.V. , Vlasuk G.P. , Hirth K.P. , Nolop K. , Bollag G. , Ibrahim P.N. , Tobin J.F. more...
Proc. Natl. Acad. Sci. U.S.A.106:262-267(2009) [PubMed] [Europe PMC] [Abstract]