Ppara ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPpara ELISA Kit for Rat(Rattus norvegicus)

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Ppara (Gene name),

Peroxisome proliferator-activated receptor alpha (Protein name ), PPARA_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ppara(Nr1c1;Ppar);

Protein name:

Peroxisome proliferator-activated receptor alpha(PPAR-alpha);

Alternative:

Nuclear receptor subfamily 1 group C member 1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterodimer; with RXRA. This heterodimerization is required for DNA binding and transactivation activity (By similarity). Interacts with AKAP13, LPIN1 and PRDM16. Also interacts with PPARBP coactivator in vitro. Interacts with NCOA3 and NCOA6 coactivators (By similarity). Interacts with CITED2; the interaction stimulates its transcriptional activity.

Function:

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

468

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

468:

ESDAALHPLL | QEIYRDMY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:25747

SMR:

P37230

Pfam:

PF00104

String:

P37230

UniGene:

Rn.9753

STRING:

10116.ENSRNOP00000038651

Uniprot:

P37230

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ELISA Kit for Rat PPAR-alpha

Cat.:

E0934m

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96T

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ELISA Kit for Rat PPAR-alpha

Cat.:

E0934d

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96T

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ELISA Kit for Rat PPAR-alpha

Cat.:

E0934h

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96T

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ELISA Kit for Rat PPAR-alpha

Cat.:

E0934r

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96T

CLIA Kit for Rat PPAR-alpha

Cat.:

U0934h

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Packing:

96T

CLIA Kit for Rat PPAR-alpha

Cat.:

U0934r

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96T

CLIA Kit for Rat PPAR-alpha

Cat.:

U0934d

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MSDS:

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96T

CLIA Kit for Rat PPAR-alpha

Cat.:

U0934m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat PPAR-alpha

Cat.:

P0934Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat PPAR-alpha

Cat.:

P0934Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat PPAR-alpha

Cat.:

P0934Rb-m

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40ug/0.2ml

Monoclonal Antibody for Rat PPAR-alpha

Protein for Rat PPAR-alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor."
Goettlicher M. , Widmark E. , Li Q. , Gustafsson J.-A.
Proc. Natl. Acad. Sci. U.S.A.89:4653-4657(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin."
Shalev A. , Siegrist-Kaiser C.A. , Yen P.M. , Wahli W. , Burger A.G. , Chin W.W. , Meier C.A.
Endocrinology137:4499-4502(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION
3.

"Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator."
Tien E.S. , Davis J.W. , Vanden Heuvel J.P.
J. Biol. Chem.279:24053-24063(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CITED2

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