Protein name:
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) ;
Alternative:
Nuclear receptor subfamily 1 group C member 3 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Heterodimer with other nuclear receptors, such as RXRA. The heterodimer with the retinoic acid receptor RXRA is called adipocyte-specific transcription factor ARF6. Interacts with NCOA6 coactivator, leading to a strong increase in transcription of target genes. Interacts with coactivator PPARBP, leading to a mild increase in transcription of target genes. Interacts with NOCA7 in a ligand-inducible manner. Interacts with NCOA1 and NCOA2 LXXLL motifs. Interacts with FAM120B, NR0B2 and TGFB1I1. Interacts with DNTTIP2. Interacts with PRDM16. Interacts with PRMT2.
Function:
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MGETLGDPPV | DPEHGAFADA | LPMSTSQEIT | MVDTEMPFWP | TNFGISSVDL |
100:
SVMDDHSHSF | DIKPFTTVDF | SSISAPHYED | IPFTRADPMV | ADYKYDLKLQ |
150:
EYQSAIKVEP | ASPPYYSEKT | QLYNRPHEEP | SNSLMAIECR | VCGDKASGFH |
200:
YGVHACEGCK | GFFRRTIRLK | LIYDRCDLNC | RIHKKSRNKC | QYCRFQKCLA |
250:
VGMSHNAIRF | GRMPQAEKEK | LLAEISSDID | QLNPESADLR | ALAKHLYDSY |
300:
IKSFPLTKAK | ARAILTGKTT | DKSPFVIYDM | NSLMMGEDKI | KFKHITPLQE |
350:
QSKEVAIRIF | QGCQFRSVEA | VQEITEYAKN | IPGFINLDLN | DQVTLLKYGV |
400:
HEIIYTMLAS | LMNKDGVLIS | EGQGFMTREF | LKSLRKPFGD | FMEPKFEFAV |
450:
KFNALELDDS | DLAIFIAVII | LSGDRPGLLN | VKPIEDIQDN | LLQALELQLK |
500:
LNHPESSQLF | AKVLQKMTDL | RQIVTEHVQL | LHVIKKTETD | MSLHPLLQEI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Dog
Pig
Mouse
Rabbit
ELISA Kit for Rat PPAR-gamma
ELISA Kit for Rat PPAR-gamma
ELISA Kit for Rat PPAR-gamma
ELISA Kit for Rat PPAR-gamma
ELISA Kit for Rat PPAR-gamma
ELISA Kit for Rat PPAR-gamma
ELISA Kit for Rat PPAR-gamma
CLIA Kit for Rat PPAR-gamma
CLIA Kit for Rat PPAR-gamma
CLIA Kit for Rat PPAR-gamma
CLIA Kit for Rat PPAR-gamma
CLIA Kit for Rat PPAR-gamma
CLIA Kit for Rat PPAR-gamma
CLIA Kit for Rat PPAR-gamma
Polyclonal Antibody for Rat PPAR-gamma
Polyclonal Antibody for Rat PPAR-gamma
Polyclonal Antibody for Rat PPAR-gamma
Polyclonal Antibody for Rat PPAR-gamma
Polyclonal Antibody for Rat PPAR-gamma
Polyclonal Antibody for Rat PPAR-gamma
Polyclonal Antibody for Rat PPAR-gamma
Monoclonal Antibody for Rat PPAR-gamma
Monoclonal Antibody for Rat PPAR-gamma
Monoclonal Antibody for Rat PPAR-gamma
Monoclonal Antibody for Rat PPAR-gamma
Monoclonal Antibody for Rat PPAR-gamma
Monoclonal Antibody for Rat PPAR-gamma
Monoclonal Antibody for Rat PPAR-gamma
Protein for Rat PPAR-gamma
Protein for Rat PPAR-gamma
Protein for Rat PPAR-gamma
Protein for Rat PPAR-gamma
Protein for Rat PPAR-gamma
Protein for Rat PPAR-gamma
Protein for Rat PPAR-gamma
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
AP Meher, AA Joshi, SR Joshi
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
strain :
Sprague-Dawley .
tissue :
Brown adipose tissue .
2.
"Down-regulation of PPAR gammma."
Tanaka T.
,
Itoh H.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain :
Sprague-Dawley .
tissue :
Adipose tissue .
3.
Escher P.
Submitted (2001-01) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Adipocyte .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
Long Evans .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-112;MUTAGENESIS OF SER-112
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION