ALPP ELISA Kit for Human(Homo sapiens) | EIAab.comALPP ELISA Kit for Human(Homo sapiens)

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ALPP (Gene name),

Alkaline phosphatase, placental type (Protein name ), PPB1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (2)

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Gene name:

ALPP(PLAP);

Protein name:

Alkaline phosphatase, placental type;

Alternative:

Placental alkaline phosphatase 1(PLAP-1);Alkaline phosphatase Regan isozyme;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer.

Function:

N/A

Subcellular Location:

Cell membrane Lipid-anchor GPI-anchor

Protein Attributes:

Sequence length:

535

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

535:

PAGTTDAAHP | GRSVVPALLP | LLAGTLLLLE | TATAP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

171800

STRING:

9606.ENSP00000375881

SMR:

P05187

KEGG:

hsa:250

Pfam:

PF00245

UniGene:

Hs.284255

String:

P05187

Uniprot:

P05187

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ELISA Kit for Human Alkaline phosphatase, placental type

Cat.:

E1219h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Alkaline phosphatase, placental type

Cat.:

U1219h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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Polyclonal Antibody for Human Alkaline phosphatase, placental type

Cat.:

P1219Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Alkaline phosphatase, placental type

Protein for Human Alkaline phosphatase, placental type

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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Citations

[1].

"Transplacental transfer of melamine"

H. Partanen, K. V hkangas , C.S.J. Woo , S. Auriola , J. Veid , Y. Chen , P. Myllynen , H. El Nezami

From:Placenta

[2].

"RhoB/ROCK mediates oxygen–glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia"

Han J, Yang B, Li Y, et al.

From:Cell and Tissue Research

References

1.

"Nucleotide sequence of the human placental alkaline phosphatase gene. Evolution of the 5' flanking region by deletion/substitution."
Knoll B.J. , Rothblum K.N. , Longley M.A.
J. Biol. Chem.263:12020-12027(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Molecular cloning and sequence analysis of human placental alkaline phosphatase."
Millan J.L.
J. Biol. Chem.261:3112-3115(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PRO-231
3.

"Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids."
Henthorn P.S. , Knoll B.J. , Raducha M. , Rothblum K.N. , Slaughter C. , Weiss M. , Lafferty M.A. , Fischer T. , Harris H.
Proc. Natl. Acad. Sci. U.S.A.83:5597-5601(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;VARIANTS LEU-25 AND HIS-263
4.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT LEU-89
tissue: Cervix.
tissue: Placenta.
6.

"Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA."
Kam W. , Clauser E. , Kim Y.S. , Kan Y.W. , Rutter W.J.
Proc. Natl. Acad. Sci. U.S.A.82:8715-8719(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-535;VARIANT LEU-25
7.

"Purification and partial sequencing of human placental alkaline phosphatase."
Ezra E. , Blacher R. , Udenfriend S.
Biochem. Biophys. Res. Commun.116:1076-1083(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 23-64
8.

"Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells."
Ovitt C.E. , Strauss A.W. , Alpers D.H. , Chou J.Y. , Boime I.
Proc. Natl. Acad. Sci. U.S.A.83:3781-3785(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 382-535
9.

"Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme."
Micanovic R. , Bailey C.A. , Brink L. , Gerber L. , Pan Y.C.E. , Hulmes J.D. , Udenfriend S.
Proc. Natl. Acad. Sci. U.S.A.85:1398-1402(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 485-535
10.

"Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase."
Micanovic R. , Gerber L.D. , Berger J. , Kodukula K. , Udenfriend S.
Proc. Natl. Acad. Sci. U.S.A.87:157-161(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR AT ASP-506
11.

"Site-specific mutations in the COOH-terminus of placental alkaline phosphatase: a single amino acid change converts a phosphatidylinositol-glycan-anchored protein to a secreted protein."
Lowe M.E.
J. Cell Biol.116:799-807(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: EFFECT OF MUTAGENESIS OF C-TERMINAL PEPTIDE ON GPI-ANCHORING
12.

"Function assignment to conserved residues in mammalian alkaline phosphatases."
Kozlenkov A. , Manes T. , Hoylaerts M.F. , Millan J.L.
J. Biol. Chem.277:22992-22999(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS
13.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity."
Le Du M.H. , Stigbrand T. , Taussig M.J. , Menez A. , Stura E.A.
J. Biol. Chem.276:9158-9165(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.82 ANGSTROMS) OF 23-535 IN COMPLEX WITH MAGNESIUM AND ZINC;COFACTOR;DISULFIDE BOND;SUBUNIT
15.

"Structural studies of human placental alkaline phosphatase in complex with functional ligands."
Llinas P. , Stura E.A. , Menez A. , Kiss Z. , Stigbrand T. , Millan J.L. , Le Du M.H.
J. Mol. Biol.350:441-451(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.57 ANGSTROMS) OF 23-506 IN COMPLEX WITH MAGNESIUM AND ZINC;GLYCOSYLATION AT ASN-144 AND ASN-271;COFACTOR;DISULFIDE BOND;SUBUNIT
16.

"Structural studies of human alkaline phosphatase in complex with strontium: implication for its secondary effect in bones."
Llinas P. , Masella M. , Stigbrand T. , Menez A. , Stura E.A. , Le Du M.H.
Protein Sci.15:1691-1700(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 23-506 IN COMPLEX WITH MAGNESIUM AND ZINC;GLYCOSYLATION AT ASN-144 AND ASN-271;COFACTOR;DISULFIDE BOND;SUBUNIT
17.

"Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site."
Stec B. , Cheltsov A. , Millan J.L.
Acta Crystallogr. F66:866-870(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.57 ANGSTROMS) OF 23-506 IN COMPLEX WITH MAGNESIUM AND ZINC;GLYCOSYLATION AT ASN-144 AND ASN-271;COFACTOR;DISULFIDE BOND;SUBUNIT;TISSUE SPECIFICITY

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