Protein name:
Peptidyl-prolyl cis-trans isomerase B (PPIase B) ;
Alternative:
Cyclophilin B ;CYP-S1 ;S-cyclophilin (SCYLP) ;Rotamase B ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Location:
Endoplasmic reticulum lumen
Melanosome
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein Attributes:
50:
MLRLSERNMK | VLLAAALIAG | SVFFLLLPGP | SAADEKKKGP | KVTVKVYFDL |
100:
RIGDEDVGRV | IFGLFGKTVP | KTVDNFVALA | TGEKGFGYKN | SKFHRVIKDF |
150:
MIQGGDFTRG | DGTGGKSIYG | ERFPDENFKL | KHYGPGWVSM | ANAGKDTNGS |
200:
QFFITTVKTA | WLDGKHVVFG | KVLEGMEVVR | KVESTKTDSR | DKPLKDVIIA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Chicken
Mouse
Rat
ELISA Kit for Human PPIase B
ELISA Kit for Human PPIase B
ELISA Kit for Human PPIase B
ELISA Kit for Human PPIase B
ELISA Kit for Human PPIase B
CLIA Kit for Human PPIase B
CLIA Kit for Human PPIase B
CLIA Kit for Human PPIase B
CLIA Kit for Human PPIase B
CLIA Kit for Human PPIase B
Polyclonal Antibody for Human PPIase B
Polyclonal Antibody for Human PPIase B
Polyclonal Antibody for Human PPIase B
Polyclonal Antibody for Human PPIase B
Polyclonal Antibody for Human PPIase B
Monoclonal Antibody for Human PPIase B
Monoclonal Antibody for Human PPIase B
Monoclonal Antibody for Human PPIase B
Monoclonal Antibody for Human PPIase B
Monoclonal Antibody for Human PPIase B
Protein for Human PPIase B
Protein for Human PPIase B
Protein for Human PPIase B
Protein for Human PPIase B
Protein for Human PPIase B
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
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more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.
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Nature440:671-675(2006)
[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
tissue :
Prostate .
tissue :
Skin .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 5-216;PROTEIN SEQUENCE OF 34-48
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 10-216
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 52-59; 64-76; 91-101; 138-150; 164-172 AND 197-207;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Fetal brain cortex .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 72-84 AND 159-165
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
13.
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue :
Melanoma .
14.
"PPIB mutations cause severe osteogenesis imperfecta."
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Pals G.
more...
Am. J. Hum. Genet.85:521-527(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN OI9
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DYM
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 39-216
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.2 ANGSTROMS) OF 34-216 IN COMPLEX WITH CLGN;MUTAGENESIS OF LYS-129;INTERACTION WITH CALR; CANX AND CLGN
19.
"Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding."
Barnes A.M.
,
Carter E.M.
,
Cabral W.A.
,
Weis M.
,
Chang W.
,
Makareeva E.
,
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Eyre D.R.
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,
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N. Engl. J. Med.362:521-528(2010)
[
PubMed ]
[
Europe PMC ]
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Abstract ]
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Cited for : VARIANT OI9 ARG-9