PLN ELISA Kit for Human(Homo sapiens) | EIAab.comPLN ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > PLN(Gene name) > Human

PLN (Gene name),

Cardiac phospholamban (Protein name ), PPLA_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

PLN(PLB);

Protein name:

Cardiac phospholamban(PLB);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homopentamer. Interacts with HAX1.

Function:

Phospholamban has been postulated to regulate the activity of the calcium pump of cardiac sarcoplasmic reticulum.

Subcellular Location:

Mitochondrion membrane Single-pass membrane protein Sarcoplasmic reticulum

Protein Attributes:

Sequence length:

Sequence:

50:

52:

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

hsa:5350

Pfam:

PF04272

SMR:

P26678

String:

P26678

MIM:

172405

STRING:

9606.ENSP00000350132

UniGene:

Hs.170839

Uniprot:

P26678

FOR

ELISA Kit for Human PLB

Cat.:

E1884h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human PLB

MSDS:

Please sign in first.

ELISA Kit for Human PLB

Cat.:

E1884p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human PLB

Cat.:

E1884b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human PLB

Cat.:

E1884m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human PLB

Cat.:

E1884d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human PLB

Cat.:

E1884c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human PLB

Cat.:

E1884r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human PLB

Cat.:

U1884d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human PLB

Cat.:

U1884r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human PLB

Cat.:

U1884c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human PLB

Cat.:

U1884h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human PLB

MSDS:

Please sign in first.

CLIA Kit for Human PLB

Cat.:

U1884b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human PLB

Cat.:

U1884m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human PLB

Cat.:

U1884p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human PLB

Cat.:

P1884Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human PLB

Cat.:

P1884Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human PLB

Cat.:

P1884Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human PLB

Monoclonal Antibody for Human PLB

Protein for Human PLB

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structure of the rabbit phospholamban gene, cloning of the human cDNA, and assignment of the gene to human chromosome 6."
Fujii J. , Zarain-Herzberg A. , Willard H.F. , Tada M. , Maclennan D.H.
J. Biol. Chem.266:11669-11675(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Cloning of human cardiac phospholamban."
Salvatore C.A. , Jacobson M.A.
Submitted (1991-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"The human phospholamban gene: structure and expression."
McTiernan C.F. , Frye C.S. , Lemster B.H. , Kinder E.A. , Ogletree-Hughes M.L. , Moravec C.S. , Feldman A.M.
J. Mol. Cell. Cardiol.31:679-692(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
5.

"Mutation of the phospholamban promoter associated with hypertrophic cardiomyopathy."
Minamisawa S. , Sato Y. , Tatsuguchi Y. , Fujino T. , Imamura S. , Uetsuka Y. , Nakazawa M. , Matsuoka R.
Biochem. Biophys. Res. Commun.304:1-4(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN CMH18
6.

"Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum."
Kaliman P. , Catalucci D. , Lam J.T. , Kondo R. , Gutierrez J.C. , Reddy S. , Palacin M. , Zorzano A. , Chien K.R. , Ruiz-Lozano P.
J. Biol. Chem.280:8016-8021(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-16 BY DMPK
7.

"Ca2+-calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise."
Rose A.J. , Kiens B. , Richter E.A.
J. Physiol. (Lond.)574:889-903(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-17 BY CAMK2
8.

"Phospholamban interacts with HAX-1, a mitochondrial protein with anti-apoptotic function."
Vafiadaki E. , Sanoudou D. , Arvanitis D.A. , Catino D.H. , Kranias E.G. , Kontrogianni-Konstantopoulos A.
J. Mol. Biol.367:65-79(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HAX1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
9.

"Lethal, hereditary mutants of phospholamban elude phosphorylation by protein kinase A."
Ceholski D.K. , Trieber C.A. , Holmes C.F. , Young H.S.
J. Biol. Chem.287:26596-26605(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CHARACTERIZATION OF VARIANTS CMD1P CYS-9 AND ARG-14 DEL;SUBCELLULAR LOCATION;PHOSPHORYLATION AT SER-16;MUTAGENESIS OF ARG-9; ARG-13; ARG-14; SER-16 AND THR-17
10.

"Solution structure of the cytoplasmic domain of phospholamban: phosphorylation leads to a local perturbation in secondary structure."
Mortishire-Smith R.J. , Pitzenberger S.M. , Burke C.J. , Middaugh C.R. , Garsky V.M. , Johnson R.G.
Biochemistry34:7603-7613(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-25
11.

"Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban."
Adams P.D. , Arkin I.T. , Engelman D.M. , Bruenger A.T.
Nat. Struct. Biol.2:154-162(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING
12.

"Using experimental information to produce a model of the transmembrane domain of the ion channel phospholamban."
Herzyk P. , Hubbard R.E.
Biophys. J.74:1203-1214(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING
13.

"The structure of phospholamban pentamer reveals a channel-like architecture in membranes."
Oxenoid K. , Chou J.J.
Proc. Natl. Acad. Sci. U.S.A.102:10870-10875(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR;SUBCELLULAR LOCATION;SUBUNIT
14.

"Structure determination of symmetric homo-oligomers by a complete search of symmetry configuration space, using NMR restraints and van der Waals packing."
Potluri S. , Yan A.K. , Chou J.J. , Donald B.R. , Bailey-Kellogg C.
Proteins65:203-219(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR;SUBUNIT
15.

"Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban."
Schmitt J.P. , Kamisago M. , Asahi M. , Li G.H. , Ahmad F. , Mende U. , Kranias E.G. , MacLennan D.H. , Seidman J.G. , Seidman C.E.
Science299:1410-1413(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMD1P CYS-9;CHARACTERIZATION OF VARIANT CMD1P CYS-9
16.

"A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy."
Haghighi K. , Kolokathis F. , Gramolini A.O. , Waggoner J.R. , Pater L. , Lynch R.A. , Fan G.C. , Tsiapras D. , Parekh R.R. , Dorn G.W. II , MacLennan D.H. , Kremastinos D.T. , Kranias E.G.
Proc. Natl. Acad. Sci. U.S.A.103:1388-1393(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMD1P ARG-14 DEL;CHARACTERIZATION OF VARIANT CMD1P ARG-14 DEL
17.

"Hydrophobic imbalance in the cytoplasmic domain of phospholamban is a determinant for lethal dilated cardiomyopathy."
Ceholski D.K. , Trieber C.A. , Young H.S.
J. Biol. Chem.287:16521-16529(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS CMD1P CYS-9 AND ARG-14 DEL;FUNCTION;SUBCELLULAR LOCATION

Product Feedback Wall

* Email:
*Comments: