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Index > Protein center > PPP1R1A(Gene name) > Human
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  • PPP1R1A (Gene name),
  • Protein phosphatase 1 regulatory subunit 1A (Protein name ),  PPR1A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PPP1R1A(IPP1);
    Protein name:
    Protein phosphatase 1 regulatory subunit 1A;
    Alternative:
    Protein phosphatase inhibitor 1(I-1;IPP-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with PPP1R15A.
    Function:
    Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
    Subcellular Location:
    Protein Attributes:
    Sequence length:
    171
    Sequence:
    50:
    MEQDNSPRKI | QFTVPLLEPH | LDPEAAEQIR | RRRPTPATLV | LTSDQSSPEI | 
    100:
    DEDRIPNPHL | KSTLAMSPRQ | RKKMTRITPT | MKELQMMVEH | HLGQQQQGEE | 
    150:
    PEGAAESTET | QESRPPGIPD | TEVESRLGTS | GTAKKTAECI | PKTHERGSKE | 
    171:
    PSTKEPSTHI | PPLDSKGANS | V
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Pfam:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    E1641d
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    E1641m
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    96T
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    ELISA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    E1641h
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    Please sign in first.
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    96T
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    ELISA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    MSDS:
    Please sign in first.
    ELISA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    E1641r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    U1641m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    U1641h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    U1641d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    MSDS:
    Please sign in first.
    CLIA Kit for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    U1641r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Polyclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Polyclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    P1641Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    P1641Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Cat.:
    P1641Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Monoclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Monoclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Monoclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Monoclonal Antibody for Human Protein phosphatase 1 regulatory subunit 1A
    Protein for Human Protein phosphatase 1 regulatory subunit 1A
    Protein for Human Protein phosphatase 1 regulatory subunit 1A
    Protein for Human Protein phosphatase 1 regulatory subunit 1A
    Protein for Human Protein phosphatase 1 regulatory subunit 1A
    Protein for Human Protein phosphatase 1 regulatory subunit 1A

    R&D Technical Data
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    Linearity
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    References
    1. 1.
      "Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor."
      Endo S. , Zhou X. , Connor J. , Wang B. , Shenolikar S.
      Biochemistry35:5220-5228(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 1-23 AND 53-61;MUTAGENESIS OF THR-35;VARIANT GLY-109
      tissue: Brain.
    2. 2.
      "Cloning of inhibitor-1 of protein phosphatase type 1 from human heart."
      Mishra S. , Tiwari N. , Sabbah H.N. , Gupta R.C.
      Submitted (2001-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLY-109
      tissue: Heart.
    3. 3.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-109
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-109
      tissue: Brain.
    5. 5.
      "Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1."
      Connor J.H. , Weiser D.C. , Li S. , Hallenbeck J.M. , Shenolikar S.
      Mol. Cell. Biol.21:6841-6850(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PPP1R15A;PHOSPHORYLATION AT THR-35
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