Gene name:
PRDX1 (PAGA;PAGB;TDPX2) ;
Protein name:
Peroxiredoxin-1 ;
Alternative:
Proliferation-associated gene protein (PAG) ;Natural killer cell-enhancing factor A (NKEF-A) ;Thioredoxin-dependent peroxide reductase 2 ;Thioredoxin peroxidase 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer; disulfide-linked, upon oxidation (By similarity). May form heterodimers with AOP2. Interacts with GDPD5; forms a mixed-disulfide with GDPD5.
Function:
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
Subcellular Location:
Cytoplasm
Melanosome
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein Attributes:
50:
MSSGNAKIGH | PAPNFKATAV | MPDGQFKDIS | LSDYKGKYVV | FFFYPLDFTF |
100:
VCPTEIIAFS | DRAEEFKKLN | CQVIGASVDS | HFCHLAWVNT | PKKQGGLGPM |
150:
NIPLVSDPKR | TIAQDYGVLK | ADEGISFRGL | FIIDDKGILR | QITVNDLPVG |
199:
RSVDETLRLV | QAFQFTDKHG | EVCPAGWKPG | SDTIKPDVQK | SKEYFSKQK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Chicken
Bovine
Rat
ELISA Kit for Human Peroxiredoxin-1
ELISA Kit for Human Peroxiredoxin-1
ELISA Kit for Human Peroxiredoxin-1
ELISA Kit for Human Peroxiredoxin-1
ELISA Kit for Human Peroxiredoxin-1
CLIA Kit for Human Peroxiredoxin-1
CLIA Kit for Human Peroxiredoxin-1
CLIA Kit for Human Peroxiredoxin-1
CLIA Kit for Human Peroxiredoxin-1
CLIA Kit for Human Peroxiredoxin-1
Polyclonal Antibody for Human Peroxiredoxin-1
Polyclonal Antibody for Human Peroxiredoxin-1
Polyclonal Antibody for Human Peroxiredoxin-1
Polyclonal Antibody for Human Peroxiredoxin-1
Polyclonal Antibody for Human Peroxiredoxin-1
Monoclonal Antibody for Human Peroxiredoxin-1
Monoclonal Antibody for Human Peroxiredoxin-1
Monoclonal Antibody for Human Peroxiredoxin-1
Monoclonal Antibody for Human Peroxiredoxin-1
Monoclonal Antibody for Human Peroxiredoxin-1
Protein for Human Peroxiredoxin-1
Protein for Human Peroxiredoxin-1
Protein for Human Peroxiredoxin-1
Protein for Human Peroxiredoxin-1
Protein for Human Peroxiredoxin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
AA Al-Masri, E El Eter, S Tayel, et al.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Urinary bladder .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 17-35; 93-136; 141-151 AND 159-190;IDENTIFICATION BY MASS SPECTROMETRY
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue :
Melanoma .
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2; LYS-7; LYS-16; LYS-27 AND LYS-35;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]