Protein name:
Thioredoxin-dependent peroxide reductase, mitochondrial ;
Alternative:
HBC189 ;Antioxidant protein 1 (AOP-1) ;Peroxiredoxin-3 ;Peroxiredoxin III (Prx-III) ;Protein MER5 homolog ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Dodecameric ring assembled from homodimeric units; disulfide-linked, upon oxidation. The rings have an approximate diameter of 150 A and a central hole of 70 A. 3-5% of the rings are interlocked by pairs. Binds MAP3K13. Interacts with NEK6.
Function:
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Subcellular Location:
Mitochondrion
Protein Attributes:
50:
MAAAVGRLLR | ASVARHVSAI | PWGISATAAL | RPAACGRTSL | TNLLCSGSSQ |
100:
AKLFSTSSSC | HAPAVTQHAP | YFKGTAVVNG | EFKDLSLDDF | KGKYLVLFFY |
150:
PLDFTFVCPT | EIVAFSDKAN | EFHDVNCEVV | AVSVDSHFSH | LAWINTPRKN |
200:
GGLGHMNIAL | LSDLTKQISR | DYGVLLEGSG | LALRGLFIID | PNGVIKHLSV |
250:
NDLPVGRSVE | ETLRLVKAFQ | YVETHGEVCP | ANWTPDSPTI | KPSPAASKEY |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
Rat
ELISA Kit for Human Thioredoxin-dependent peroxide reductase, mitochondrial
ELISA Kit for Human Thioredoxin-dependent peroxide reductase, mitochondrial
ELISA Kit for Human Thioredoxin-dependent peroxide reductase, mitochondrial
ELISA Kit for Human Thioredoxin-dependent peroxide reductase, mitochondrial
CLIA Kit for Human Thioredoxin-dependent peroxide reductase, mitochondrial
CLIA Kit for Human Thioredoxin-dependent peroxide reductase, mitochondrial
CLIA Kit for Human Thioredoxin-dependent peroxide reductase, mitochondrial
CLIA Kit for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Polyclonal Antibody for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Polyclonal Antibody for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Polyclonal Antibody for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Polyclonal Antibody for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Monoclonal Antibody for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Monoclonal Antibody for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Monoclonal Antibody for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Monoclonal Antibody for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Protein for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Protein for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Protein for Human Thioredoxin-dependent peroxide reductase, mitochondrial
Protein for Human Thioredoxin-dependent peroxide reductase, mitochondrial
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Blood .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Lung .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Electrophoresis13:992-1001(1992)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 63-72 (ISOFORM 1)
tissue :
Liver .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 74-93; 149-166 AND 171-214 (ISOFORM 1);IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Brain .
tissue :
Cajal-Retzius cell .
tissue :
Fetal brain cortex .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : OVEROXIDATION AT CYS-108
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH MAP3K13
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-91;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NEK6
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Lim K.L.
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Dachsel J.
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Tan E.K.
Hum. Mutat.32:1390-1397(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH LRRK2;PHOSPHORYLATION AT THR-146;MUTAGENESIS OF THR-146