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Index > Protein center > PRL(Gene name) > Human
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  • PRL (Gene name),
  • Prolactin (Protein name ),  PRL_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    PRL;
    Protein name:
    Prolactin(PRL);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Prolactin acts primarily on the mammary gland by promoting lactation.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    227
    Sequence:
    50:
    MNIKGSPWKG | SLLLLLVSNL | LLCQSVAPLP | ICPGGAARCQ | VTLRDLFDRA | 
    100:
    VVLSHYIHNL | SSEMFSEFDK | RYTHGRGFIT | KAINSCHTSS | LATPEDKEQA | 
    150:
    QQMNQKDFLS | LIVSILRSWN | EPLYHLVTEV | RGMQEAPEAI | LSKAVEIEEQ | 
    200:
    TKRLLEGMEL | IVSQVHPETK | ENEIYPVWSG | LPSLQMADEE | SRLSAYYNLL | 
    227:
    HCLRRDSHKI | DNYLKLLKCR | IIHNNNC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    KEGG:
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human PRL
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    E0846r
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    ELISA Kit for Human PRL
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    ELISA Kit for Human PRL
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    E0846b
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    ELISA Kit for Human PRL
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    E0846h
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    ELISA Kit for Human PRL
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    ELISA Kit for Human PRL
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    E0846c
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    ELISA Kit for Human PRL
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    E0846p
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    96T
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    CLIA Kit for Human PRL
    MSDS:
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    CLIA Kit for Human PRL
    Cat.:
    U0846p
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    96T
    CLIA Kit for Human PRL
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    U0846c
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    CLIA Kit for Human PRL
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    96T
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    CLIA Kit for Human PRL
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    MSDS:
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    96T
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    CLIA Kit for Human PRL
    Cat.:
    U0846b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human PRL
    Cat.:
    U0846h
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human PRL
    Polyclonal Antibody for Human PRL
    Polyclonal Antibody for Human PRL
    Polyclonal Antibody for Human PRL
    Cat.:
    P0846Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PRL
    Polyclonal Antibody for Human PRL
    Cat.:
    P0846Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PRL
    Cat.:
    P0846Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human PRL
    Cat.:
    M0846h
    Price:
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    Packing:
    40ug
    Monoclonal Antibody for Human PRL
    Monoclonal Antibody for Human PRL
    Monoclonal Antibody for Human PRL
    Monoclonal Antibody for Human PRL
    Monoclonal Antibody for Human PRL
    Monoclonal Antibody for Human PRL
    Protein for Human PRL
    Protein for Human PRL
    Protein for Human PRL
    Protein for Human PRL
    Protein for Human PRL
    Protein for Human PRL
    Protein for Human PRL

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    References
    1. 1.
      "Human prolactin. cDNA structural analysis and evolutionary comparisons."
      Cooke N.E. , Coit D. , Shine J. , Baxter J.D. , Martial J.A.
      J. Biol. Chem.256:4007-4016(1981) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Isolation and characterization of the human prolactin gene."
      Truong A.T. , Duez C. , Belayew A. , Renard A. , Pictet R.L. , Bell G.I. , Martial J.A.
      EMBO J.3:429-437(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "A placenta-specific 5'non-coding exon of human prolactin."
      Hiraoka Y. , Tatsumi K. , Shiozawa M. , Aiso S. , Fukasawa T. , Yasuda K. , Miyai K.
      Mol. Cell. Endocrinol.75:71-80(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Testis.
    5. 5.
      "Molecular cloning and nucleotide sequence of DNA complementary to human decidual prolactin mRNA."
      Takahashi H. , Nabeshima Y. , Nabeshima Y. , Ogata K. , Takeuchi S.
      J. Biochem.95:1491-1499(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-227
    6. 6.
      "Expression of the prolactin gene in normal and neoplastic human breast tissues and human mammary cell lines: promoter usage and alternative mRNA splicing."
      Shaw-Bruha C.M. , Pirrucello S.J. , Shull J.D.
      Breast Cancer Res. Treat.44:243-253(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-201
      tissue: Mammary gland.
    7. 7.
      "Human pituitary prolactin (hPRL): the entire linear amino acid sequence."
      Shome B. , Parlow A.F.
      J. Clin. Endocrinol. Metab.45:1112-1115(1977) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-227
    8. 8.
      "High sensitivity automated sequence determination of polypeptides."
      Jacobs J.W. , Niall H.D.
      J. Biol. Chem.250:3629-3636(1975) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-53
    9. 9.
      "Immunoglobulin G subclasses and prolactin (PRL) isoforms in macroprolactinemia due to anti-PRL autoantibodies."
      Hattori N. , Ikekubo K. , Nakaya Y. , Kitagawa K. , Inagaki C.
      J. Clin. Endocrinol. Metab.90:3036-3044(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-163 AND SER-194
    10. 10.
      "The tertiary structure and backbone dynamics of human prolactin."
      Keeler C. , Dannies P.S. , Hodsdon M.E.
      J. Mol. Biol.328:1105-1121(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 29-227
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 29-227;INTERACTION WITH PRLR
    12. 12.
      "Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL."
      Jomain J.-B. , Tallet E. , Broutin I. , Hoos S. , van Agthoven J. , Ducruix A. , Kelly P.A. , Kragelund B.B. , England P. , Goffin V.
      J. Biol. Chem.282:33118-33131(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 38-227;MUTAGENESIS OF GLY-157
    13. 13.
      "Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor."
      Svensson L.A. , Bondensgaard K. , Noerskov-Lauritsen L. , Christensen L. , Becker P. , Andersen M.D. , Maltesen M.J. , Rand K.D. , Breinholt J.
      J. Biol. Chem.283:19085-19094(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 41-227 IN COMPLEX WITH PRLR;IDENTIFICATION BY MASS SPECTROMETRY;DISULFIDE BONDS
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