Protein name:
Prokineticin-1 ;
Alternative:
Endocrine-gland-derived vascular endothelial growth factor (EG-VEGF) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
Subcellular Location:
Secreted
Protein Attributes:
50:
MRGAVQVFIM | LLLATVSDCA | VITGACERDV | QCGAGTCCAI | SLWLRGLRLC |
100:
TPLGREGEEC | HPGSHKIPFF | RKRQHHTCPC | SPSLLCSRFP | DGRYRCSQDL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat Prokineticin-1
ELISA Kit for Rat Prokineticin-1
ELISA Kit for Rat Prokineticin-1
CLIA Kit for Rat Prokineticin-1
CLIA Kit for Rat Prokineticin-1
CLIA Kit for Rat Prokineticin-1
Polyclonal Antibody for Rat Prokineticin-1
Polyclonal Antibody for Rat Prokineticin-1
Polyclonal Antibody for Rat Prokineticin-1
Monoclonal Antibody for Rat Prokineticin-1
Monoclonal Antibody for Rat Prokineticin-1
Monoclonal Antibody for Rat Prokineticin-1
Protein for Rat Prokineticin-1
Protein for Rat Prokineticin-1
Protein for Rat Prokineticin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors."
Masuda Y.
,
Takatsu Y.
,
Terao Y.
,
Kumano S.
,
Ishibashi Y.
,
Suenaga M.
,
Abe M.
,
Fukusumi S.
,
Watanabe T.
,
Shintani Y.
,
Yamada T.
,
Hinuma S.
,
Inatomi N.
,
Ohtaki T.
,
Onda H.
,
Fujino M.
Biochem. Biophys. Res. Commun.293:396-402(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .