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Index > Protein center > PRSS8(Gene name) > Human
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  • PRSS8 (Gene name),
  • Prostasin (Protein name ),  PRSS8_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PRSS8;
    Protein name:
    Prostasin;
    Alternative:
    Serine protease 8;Serine protease 8(CAP1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of two chains, light and heavy, held by a disulfide bond.
    Function:
    Possesses a trypsin-like cleavage specificity.
    Subcellular Location:
    Prostasin heavy chain Secreted extracellular space Found in the seminal fluid. Secreted after cleavage of its C-terminus.
    Protein Attributes:
    Sequence length:
    343
    Sequence:
    50:
    MAQKGVLGPG | QLGAVAILLY | LGLLRSGTGA | EGAEAPCGVA | PQARITGGSS | 
    100:
    AVAGQWPWQV | SITYEGVHVC | GGSLVSEQWV | LSAAHCFPSE | HHKEAYEVKL | 
    150:
    GAHQLDSYSE | DAKVSTLKDI | IPHPSYLQEG | SQGDIALLQL | SRPITFSRYI | 
    200:
    RPICLPAANA | SFPNGLHCTV | TGWGHVAPSV | SLLTPKPLQQ | LEVPLISRET | 
    250:
    CNCLYNIDAK | PEEPHFVQED | MVCAGYVEGG | KDACQGDSGG | PLSCPVEGLW | 
    300:
    YLTGIVSWGD | ACGARNRPGV | YTLASSYASW | IQSKVTELQP | RVVPQTQESQ | 
    343:
    PDSNLCGSHL | AFSSAPAQGL | LRPILFLPLG | LALGLLSPWL | SEH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    Pfam:
    KEGG:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Prostasin
    Cat.:
    E12535m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Prostasin
    Cat.:
    E12535r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Prostasin
    Cat.:
    E12535h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Prostasin
    Cat.:
    U12535m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Prostasin
    Cat.:
    U12535r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Prostasin
    Cat.:
    U12535h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Prostasin
    Cat.:
    P12535Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Prostasin
    Polyclonal Antibody for Human Prostasin
    Monoclonal Antibody for Human Prostasin
    Monoclonal Antibody for Human Prostasin
    Monoclonal Antibody for Human Prostasin
    Protein for Human Prostasin
    Protein for Human Prostasin
    Protein for Human Prostasin

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning, tissue-specific expression, and cellular localization of human prostasin mRNA."
      Yu J.X. , Chao L. , Chao J.
      J. Biol. Chem.270:13483-13489(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
      tissue: Prostate.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Colon.
    3. 3.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    5. 5.
      "Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland."
      Yu J.X. , Chao L. , Chao J.
      J. Biol. Chem.269:18843-18848(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 45-64
      tissue: Semen.
    6. 6.
      "Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in JME/CF15 cells, a cystic fibrosis airway epithelial cell line."
      Tong Z. , Illek B. , Bhagwandin V.J. , Verghese G.M. , Caughey G.H.
      Am. J. Physiol.287:L928-L935(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN SODIUM CHANNELS ACTIVATION
    7. 7.
      "Biochemical characterization of prostasin, a channel activating protease."
      Shipway A. , Danahay H. , Williams J.A. , Tully D.C. , Backes B.J. , Harris J.L.
      Biochem. Biophys. Res. Commun.324:953-963(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBSTRATE SPECIFICITY
    8. 8.
      "Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations."
      Spraggon G. , Hornsby M. , Shipway A. , Tully D.C. , Bursulaya B. , Danahay H. , Harris J.L. , Lesley S.A.
      Protein Sci.18:1081-1094(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.3 ANGSTROMS) OF 45-305 IN COMPLEX WITH INHIBITOR;DISULFIDE BONDS
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