Protein name:
Pulmonary surfactant-associated protein B (SP-B) ;
Alternative:
6 kDa protein ;18 kDa pulmonary-surfactant protein ;Pulmonary surfactant-associated proteolipid SPL(Phe) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer; disulfide-linked.
Function:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
Subcellular Location:
Secreted
extracellular space
surface film
Protein Attributes:
50:
MAESHLLQWL | LLLLPTLCGP | GTAAWTTSSL | ACAQGPEFWC | QSLEQALQCR |
100:
ALGHCLQEVW | GHVGADDLCQ | ECEDIVHILN | KMAKEAIFQD | TMRKFLEQEC |
150:
NVLPLKLLMP | QCNQVLDDYF | PLVIDYFQNQ | TDSNGICMHL | GLCKSRQPEP |
200:
EQEPGMSDPL | PKPLRDPLPD | PLLDKLVLPV | LPGALQARPG | PHTQDLSEQQ |
250:
FPIPLPYCWL | CRALIKRIQA | MIPKGALAVA | VAQVCRVVPL | VAGGICQCLA |
300:
ERYSVILLDT | LLGRMLPQLV | CRLVLRCSMD | DSAGPRSPTG | EWLPRDSECH |
350:
LCMSVTTQAG | NSSEQAIPQA | MLQACVGSWL | DREKCKQFVE | QHTPQLLTLV |
381:
PRGWDAHTTC | QALGVCGTMS | SPLQCIHSPD | L
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Pig
Rabbit
Mouse
Rat
Dog
Polyclonal Antibody for Human SP-B
Polyclonal Antibody for Human SP-B
Polyclonal Antibody for Human SP-B
Polyclonal Antibody for Human SP-B
Polyclonal Antibody for Human SP-B
Polyclonal Antibody for Human SP-B
Polyclonal Antibody for Human SP-B
Monoclonal Antibody for Human SP-B
Monoclonal Antibody for Human SP-B
Monoclonal Antibody for Human SP-B
Monoclonal Antibody for Human SP-B
Monoclonal Antibody for Human SP-B
Monoclonal Antibody for Human SP-B
Monoclonal Antibody for Human SP-B
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 201-214
tissue :
Lung .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-228
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ILE-131; PHE-176 AND HIS-272
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 99-381;VARIANT ARG-228
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 139-381
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 201-279;DISULFIDE BONDS;VARIANT ILE-228
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY FTIR OF 201-225
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 208-278
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT SMDP1 CYS-236
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT ILE-131
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN SUSCEPTIBILITY TO RDS